Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 233686 | . | C | A | CCDS3853.1:NM_004168.2:c.990taC>taA_NP_004159.2:p.330Y>* | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | TYR | A:298 | A:330 | 55.0 | 0.239 | H | -77.4 | -24.0 | 55.0 | 0.239 | 0.0 | ||||||
TYR | C:298 | C:330 | 58.0 | 0.252 | H | -75.9 | -20.7 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | TYR | A:330 | A:288 | 83.0 | 0.361 | H | -82.4 | -62.0 | 83.0 | 0.361 | 0.0 | ||||||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | TYR | A:330 | A:288 | 71.0 | 0.309 | H | -68.3 | -38.2 | 71.0 | 0.309 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:288 | A:288 | 76.0 | 0.33 | S | -75.8 | -21.0 | 76.0 | 0.33 | 0.0 |
HOH |
2.968 |
CB |
O |
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1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:288 | A:288 | 77.0 | 0.335 | S | -77.4 | -25.9 | 77.0 | 0.335 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 72.0 | 0.313 | H | -83.9 | -53.4 | 72.0 | 0.313 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 61.0 | 0.265 | H | -70.5 | -52.0 | 61.0 | 0.265 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 69.0 | 0.3 | H | -103.1 | -35.3 | 69.0 | 0.3 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 82.0 | 0.357 | S | -93.5 | -67.3 | 82.0 | 0.357 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 69.0 | 0.3 | H | -82.4 | -75.3 | 69.0 | 0.3 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 69.0 | 0.3 | S | -80.0 | -42.2 | 69.0 | 0.3 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 71.0 | 0.309 | H | -78.2 | -56.2 | 71.0 | 0.309 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 79.0 | 0.343 | H | -88.2 | -28.6 | 79.0 | 0.343 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 69.0 | 0.3 | H | -76.7 | -52.9 | 69.0 | 0.3 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 82.0 | 0.357 | H | -91.6 | -61.5 | 82.0 | 0.357 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 87.0 | 0.378 | H | -93.1 | -61.6 | 87.0 | 0.378 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 69.0 | 0.3 | H | -72.4 | -42.7 | 69.0 | 0.3 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 62.0 | 0.27 | S | -96.8 | -60.8 | 62.0 | 0.27 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 75.0 | 0.326 | T | -102.3 | -64.5 | 75.0 | 0.326 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 79.0 | 0.343 | S | -100.8 | -43.1 | 79.0 | 0.343 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 75.0 | 0.326 | H | -83.7 | -36.1 | 75.0 | 0.326 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:288 | A:288 | 72.0 | 0.313 | H | -78.6 | -88.2 | 72.0 | 0.313 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:288 | A:288 | 47.0 | 0.204 | S | -72.5 | -33.3 | 47.0 | 0.204 | 0.0 |
HOH |
4.492 |
O |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:288 | A:288 | 57.0 | 0.248 | H | -73.2 | -33.5 | 57.0 | 0.248 | 0.0 |
HOH |
9.777 |
O |
O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:287 | A:287 | 62.0 | 0.27 | H | -69.8 | -25.0 | 62.0 | 0.27 | 0.0 |
UNL HOH |
8.262 2.975 |
O O |
O1 O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:287 | A:287 | 66.0 | 0.287 | H | -96.5 | -24.5 | 66.0 | 0.287 | 0.0 |
HOH |
7.138 |
CD1 |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:287 | A:287 | 59.0 | 0.257 | H | -80.4 | -28.2 | 59.0 | 0.257 | 0.0 |
UNL UNL UNL HOH |
3.520 7.267 3.914 2.634 |
O OH O OH |
O1 O O O |
||
TYR | E:287 | N:287 | 59.0 | 0.257 | H | -80.6 | -27.6 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:287 | A:287 | 59.0 | 0.257 | H | -80.0 | -31.8 | 59.0 | 0.257 | 0.0 |
HOH |
2.597 |
O |
O |
||
TYR | E:287 | N:287 | 61.0 | 0.265 | H | -80.3 | -31.2 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:287 | A:287 | 69.0 | 0.3 | H | -74.6 | -40.0 | 69.0 | 0.3 | 0.0 |
UNL HOH |
8.329 5.229 |
O O |
O1 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | TYR | A:287 | A:287 | 58.0 | 0.252 | H | -83.6 | -31.8 | 58.0 | 0.252 | 0.0 |
HOH |
2.660 |
OH |
O |
||
TYR | E:287 | N:287 | 59.0 | 0.257 | H | -84.6 | -31.1 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 64.0 | 0.278 | H | -77.1 | -36.0 | 64.0 | 0.278 | 0.0 |
HOH |
6.996 |
CD2 |
O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 62.0 | 0.27 | H | -77.7 | -44.0 | 62.0 | 0.27 | 0.0 |
HOH |
6.918 |
O |
O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 64.0 | 0.278 | H | -75.0 | -42.9 | 64.0 | 0.278 | 0.0 |
HOH |
5.835 |
O |
O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | TYR | A:287 | A:287 | 61.0 | 0.265 | H | -80.2 | -42.4 | 61.0 | 0.265 | 0.0 | ||||||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 63.0 | 0.274 | H | -79.2 | -41.8 | 63.0 | 0.274 | 0.0 | ||||||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 62.0 | 0.27 | H | -80.3 | -34.3 | 62.0 | 0.27 | 0.0 |
HOH |
7.258 |
CD2 |
O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:287 | A:287 | 61.0 | 0.265 | H | -81.2 | -33.0 | 61.0 | 0.265 | 0.0 |
HOH |
5.271 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | TYR | A:330 | A:330 | 60.0 | 0.261 | H | -82.9 | -33.4 |