Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 233696 | . | G | A | CCDS3853.1:NM_004168.2:c.1000Gcg>Acg_NP_004159.2:p.334A>T | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ALA | A:302 | A:334 | 45.0 | 0.391 | T | -86.3 | -21.5 | 45.0 | 0.391 | 0.0 | ||||||
ALA | C:302 | C:334 | 47.0 | 0.409 | T | -82.4 | -16.8 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ALA | A:334 | A:292 | 18.0 | 0.157 | T | -70.6 | -43.1 | 18.0 | 0.157 | 0.0 | ||||||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:334 | A:292 | 27.0 | 0.235 | T | -88.2 | -21.9 | 27.0 | 0.235 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:292 | A:292 | 21.0 | 0.183 | T | -69.2 | -33.3 | 21.0 | 0.183 | 0.0 |
HOH |
4.551 |
CB |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:292 | A:292 | 22.0 | 0.191 | T | -65.6 | -37.8 | 22.0 | 0.191 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 22.0 | 0.191 | T | -91.1 | -10.1 | 22.0 | 0.191 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 27.0 | 0.235 | S | -78.1 | -22.0 | 27.0 | 0.235 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 24.0 | 0.209 | T | -87.4 | -19.7 | 24.0 | 0.209 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 24.0 | 0.209 | S | -92.7 | -19.0 | 24.0 | 0.209 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 18.0 | 0.157 | T | -83.8 | -15.4 | 18.0 | 0.157 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 23.0 | 0.2 | S | -76.9 | -27.6 | 23.0 | 0.2 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 21.0 | 0.183 | T | -79.5 | -16.9 | 21.0 | 0.183 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 16.0 | 0.139 | T | -141.7 | -36.9 | 16.0 | 0.139 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 21.0 | 0.183 | S | -89.7 | -17.1 | 21.0 | 0.183 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 19.0 | 0.165 | S | -88.5 | -27.6 | 19.0 | 0.165 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 23.0 | 0.2 | S | -86.8 | -16.8 | 23.0 | 0.2 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 23.0 | 0.2 | S | -87.4 | -24.8 | 23.0 | 0.2 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 14.0 | 0.122 | S | -117.5 | 31.9 | 14.0 | 0.122 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 22.0 | 0.191 | S | -99.0 | -22.2 | 22.0 | 0.191 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 33.0 | 0.287 | S | -108.4 | 3.9 | 33.0 | 0.287 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 22.0 | 0.191 | T | -80.6 | -15.9 | 22.0 | 0.191 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:292 | A:292 | 26.0 | 0.226 | T | -110.3 | -16.8 | 26.0 | 0.226 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:292 | A:292 | 25.0 | 0.217 | T | -71.5 | -25.0 | 25.0 | 0.217 | 0.0 |
HOH |
6.884 |
CA |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:292 | A:292 | 27.0 | 0.235 | T | -82.8 | -23.9 | 27.0 | 0.235 | 0.0 |
HOH |
3.995 |
O |
O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:291 | A:291 | 24.0 | 0.209 | T | -69.0 | -31.7 | 24.0 | 0.209 | 0.0 |
UNL HOH |
6.093 2.815 |
N O |
O1 O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:291 | A:291 | 25.0 | 0.217 | T | -75.0 | -25.0 | 25.0 | 0.217 | 0.0 |
HOH |
2.532 |
O |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:291 | A:291 | 25.0 | 0.217 | T | -77.4 | -28.7 | 25.0 | 0.217 | 0.0 |
UNL UNL UNL UNL HOH |
6.285 6.869 3.886 7.929 2.796 |
O CB CB N O |
C2 O1 C15 O O |
||
ALA | E:291 | N:291 | 23.0 | 0.2 | T | -78.9 | -27.8 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:291 | A:291 | 26.0 | 0.226 | T | -72.9 | -22.9 | 26.0 | 0.226 | 0.0 |
HOH |
2.703 |
O |
O |
||
ALA | E:291 | N:291 | 25.0 | 0.217 | T | -72.4 | -23.7 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:291 | A:291 | 26.0 | 0.226 | T | -66.0 | -21.2 | 26.0 | 0.226 | 0.0 |
UNL HOH |
6.476 4.425 |
N N |
O1 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ALA | A:291 | A:291 | 26.0 | 0.226 | T | -67.3 | -30.7 | 26.0 | 0.226 | 0.0 |
UNL HOH |
9.426 2.870 |
O O |
O6 O |
||
ALA | E:291 | N:291 | 25.0 | 0.217 | T | -67.1 | -29.9 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 25.0 | 0.217 | T | -77.6 | -21.5 | 25.0 | 0.217 | 0.0 |
HOH |
2.921 |
O |
O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 22.0 | 0.191 | T | -79.3 | -23.2 | 22.0 | 0.191 | 0.0 |
UNL HOH |
6.563 3.871 |
CB O |
O O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 24.0 | 0.209 | T | -71.0 | -33.5 | 24.0 | 0.209 | 0.0 |
HOH |
2.723 |
O |
O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ALA | A:291 | A:291 | 23.0 | 0.2 | T | -78.6 | -23.0 | 23.0 | 0.2 | 0.0 | ||||||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 23.0 | 0.2 | T | -84.7 | -29.2 | 23.0 | 0.2 | 0.0 | ||||||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 24.0 | 0.209 | T | -79.2 | -34.7 | 24.0 | 0.209 | 0.0 |
UNL HOH |
9.804 3.013 |
O O |
O O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:291 | A:291 | 26.0 | 0.226 | T | -75.8 | -27.9 | 26.0 | 0.226 | 0.0 |
UNL HOH |
3.486 2.511 |
O O |
O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ALA | A:334 | A:334 | 25.0 | 0.217 | T | -74.9 | -21.4 |