Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 235351 | . | C | A | CCDS3853.1:NM_004168.2:c.1157aCa>aAa_NP_004159.2:p.386T>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | THR | A:354 | A:386 | 39.0 | 0.279 | H | -65.0 | -46.8 | 16.0 | 0.114 | 0.165 |
B:Q9NX18:0.164 |
HOH |
8.867 |
O |
O |
|
| THR | C:354 | C:386 | 45.0 | 0.321 | H | -64.5 | -45.6 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | THR | A:386 | A:344 | 45.0 | 0.321 | H | -72.3 | -23.6 | 13.0 | 0.093 | 0.228 |
B:Q007T0:0.229 |
FAD FES HOH |
9.481 9.684 9.007 |
OG1 CG2 O |
C7M S2 O |
|
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | THR | A:386 | A:344 | 50.0 | 0.357 | H | -80.1 | -17.6 | 16.0 | 0.114 | 0.243 |
B:Q007T0:0.243 |
FAD FES |
9.231 9.236 |
OG1 CG2 |
C7M S2 |
|
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:344 | A:344 | 30.0 | 0.214 | H | -65.9 | -31.4 | 8.0 | 0.057 | 0.157 |
B:Q007T0:0.157 |
FAD HOH |
9.199 2.951 |
OG1 CG2 |
C7M O |
|
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:344 | A:344 | 31.0 | 0.221 | H | -59.4 | -32.4 | 8.0 | 0.057 | 0.164 |
B:None:0.164 |
FAD |
9.541 |
OG1 |
C7M |
|
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 44.0 | 0.314 | H | -75.1 | -18.1 | 16.0 | 0.114 | 0.2 |
B:Q007T0:0.2 |
FAD FES |
9.603 9.642 |
OG1 CG2 |
C7M S1 |
|
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 47.0 | 0.336 | H | -73.5 | -19.6 | 20.0 | 0.143 | 0.193 |
B:Q007T0:0.193 |
FES |
9.649 |
CG2 |
S2 |
|
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 36.0 | 0.257 | H | -71.8 | -20.4 | 13.0 | 0.093 | 0.164 |
B:Q007T0:0.164 |
FAD |
9.666 |
OG1 |
C7M |
|
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 41.0 | 0.293 | H | -67.8 | -25.6 | 11.0 | 0.079 | 0.214 |
B:Q007T0:0.214 |
FAD FES |
9.702 9.500 |
OG1 CG2 |
C7M S1 |
|
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 43.0 | 0.307 | H | -72.8 | -22.7 | 15.0 | 0.107 | 0.2 |
B:Q007T0:0.2 |
FAD FES |
9.438 9.615 |
OG1 CG2 |
C7M S1 |
|
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 51.0 | 0.364 | H | -77.2 | -18.3 | 18.0 | 0.129 | 0.235 |
B:Q007T0:0.236 |
FES |
9.708 |
CG2 |
S2 |
|
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 42.0 | 0.3 | H | -66.1 | -20.9 | 17.0 | 0.121 | 0.179 |
B:Q007T0:0.179 |
FES |
9.767 |
CG2 |
S1 |
|
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 38.0 | 0.271 | H | -69.4 | -31.0 | 9.0 | 0.064 | 0.207 |
B:Q007T0:0.207 |
FES |
9.510 |
CG2 |
S1 |
|
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 43.0 | 0.307 | H | -73.8 | -11.2 | 15.0 | 0.107 | 0.2 |
B:Q007T0:0.2 |
FES |
9.916 |
CG2 |
S1 |
|
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 45.0 | 0.321 | H | -74.3 | -32.0 | 10.0 | 0.071 | 0.25 |
B:Q007T0:0.25 |
FAD FES |
9.659 9.937 |
CG2 CG2 |
C7M S2 |
|
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 44.0 | 0.314 | H | -71.3 | -26.6 | 12.0 | 0.086 | 0.228 |
B:Q007T0:0.229 |
FAD FES |
9.864 9.770 |
CG2 CG2 |
C7M S1 |
|
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 44.0 | 0.314 | H | -70.5 | -26.1 | 19.0 | 0.136 | 0.178 |
B:Q007T0:0.179 |
FAD FES |
9.676 9.762 |
OG1 CG2 |
C7M S2 |
|
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 38.0 | 0.271 | H | -72.8 | -23.3 | 14.0 | 0.1 | 0.171 |
B:Q007T0:0.171 |
FES |
9.767 |
CG2 |
S2 |
|
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 39.0 | 0.279 | H | -69.9 | -20.6 | 12.0 | 0.086 | 0.193 |
B:Q007T0:0.193 |
FAD FES |
9.550 9.358 |
OG1 CG2 |
C7M S2 |
|
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 41.0 | 0.293 | H | -67.0 | -28.0 | 10.0 | 0.071 | 0.222 |
B:Q007T0:0.221 |
FES |
9.811 |
CG2 |
S2 |
|
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 33.0 | 0.236 | H | -77.4 | -22.3 | 17.0 | 0.121 | 0.115 |
B:Q007T0:0.114 |
FAD |
9.094 |
CG2 |
C7M |
|
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:344 | A:344 | 28.0 | 0.2 | H | -72.3 | -23.8 | 14.0 | 0.1 | 0.1 |
B:Q007T0:0.1 |
FAD |
9.607 |
OG1 |
C7M |
|
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:344 | A:344 | 38.0 | 0.271 | H | -66.7 | -34.5 | 15.0 | 0.107 | 0.164 |
B:Q007T0:0.164 |
FAD FES HOH |
9.489 9.874 3.166 |
CG2 CG2 CG2 |
C7M S1 O |
|
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:344 | A:344 | 41.0 | 0.293 | H | -75.9 | -19.9 | 19.0 | 0.136 | 0.157 |
B:Q007T0:0.157 |
FAD FES |
9.602 9.951 |
OG1 CG2 |
C7M S1 |
|
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:343 | A:343 | 31.0 | 0.221 | H | -58.9 | -47.0 | 14.0 | 0.1 | 0.121 |
B:Q9YHT2:0.121 |
FAD HOH |
9.012 2.339 |
CG2 OG1 |
C7M O |
|
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:343 | A:343 | 29.0 | 0.207 | H | -62.6 | -35.3 | 16.0 | 0.114 | 0.093 |
B:3851612:0.093 |
FAD HOH |
8.948 2.659 |
CG2 OG1 |
C7M O |
|
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:343 | A:343 | 33.0 | 0.236 | H | -60.0 | -46.1 | 14.0 | 0.1 | 0.136 |
B:Q9YHT2:0.136 |
FAD UNL UNL UNL HOH |
9.687 7.383 8.185 8.769 2.401 |
CG2 O N N OG1 |
C7M O2 O O O |
|
| THR | E:343 | N:343 | 33.0 | 0.236 | H | -55.7 | -47.1 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:343 | A:343 | 33.0 | 0.236 | H | -62.8 | -42.9 | 15.0 | 0.107 | 0.129 |
B:Q9YHT2:0.129 |
FAD HOH |
9.450 2.609 |
CG2 OG1 |
C7M O |
|
| THR | E:343 | N:343 | 33.0 | 0.236 | H | -62.1 | -40.9 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:343 | A:343 | 34.0 | 0.243 | H | -81.2 | -46.6 | 17.0 | 0.121 | 0.122 |
B:Q9YHT2:0.121 |
FAD HOH |
9.312 2.859 |
OG1 OG1 |
C7M O |
|
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | THR | A:343 | A:343 | 34.0 | 0.243 | H | -63.9 | -44.7 | 18.0 | 0.129 | 0.114 |
B:Q9YHT2:0.114 |
FAD HOH |
9.528 2.541 |
CG2 OG1 |
C7M O |
|
| THR | E:343 | N:343 | 33.0 | 0.236 | H | -63.1 | -44.3 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 33.0 | 0.236 | H | -66.8 | -40.7 | 14.0 | 0.1 | 0.136 |
B:Q9YHT2:0.136 |
FAD HOH |
9.360 2.552 |
CG2 OG1 |
C7M O |
|
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 32.0 | 0.229 | H | -68.4 | -39.4 | 21.0 | 0.15 | 0.079 |
B:Q9YHT2:0.079 |
FAD UNL UNL HOH |
9.534 3.218 6.114 2.669 |
CG2 OG1 OG1 OG1 |
C7M N3 C O |
|
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 32.0 | 0.229 | H | -66.3 | -36.7 | 17.0 | 0.121 | 0.108 |
B:Q9YHT2:0.107 |
FAD UNL HOH |
9.410 4.649 2.630 |
CG2 OG1 OG1 |
C7M O O |
|
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | THR | A:343 | A:343 | 34.0 | 0.243 | H | -62.7 | -40.7 | 16.0 | 0.114 | 0.129 |
B:Q9YHT2:0.129 |
FAD UNL HOH |
9.465 9.255 3.110 |
CG2 N OG1 |
C7M N3 O |
|
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 34.0 | 0.243 | H | -67.7 | -40.4 | 16.0 | 0.114 | 0.129 |
B:Q9YHT2:0.129 |
FAD UNL HOH |
9.584 3.498 4.894 |
CG2 CG2 OG1 |
C7M O O |
|
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 35.0 | 0.25 | H | -64.3 | -42.3 | 19.0 | 0.136 | 0.114 |
B:Q9YHT2:0.114 |
FAD UNL UNL UNL HOH |
9.505 2.716 9.718 8.883 3.304 |
CG2 OG1 O OG1 CG2 |
C7M O O2 O O |
|
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:343 | A:343 | 34.0 | 0.243 | H | -65.4 | -37.9 | 13.0 | 0.093 | 0.15 |
B:Q9YHT2:0.15 |
FAD UNL UNL HOH |
9.449 9.723 3.772 2.565 |
CG2 CG2 OG1 OG1 |
C7M O O O |
|
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | THR | A:386 | A:386 | 29.0 | 0.207 | H | -62.2 | -43.2 | |