Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 235384 | . | A | C | CCDS3853.1:NM_004168.2:c.1190aAg>aCg_NP_004159.2:p.397K>T | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | LYS | A:365 | A:397 | 148.0 | 0.74 | T | -141.2 | -8.1 | 148.0 | 0.74 | 0.0 | ||||||
| LYS | C:365 | C:397 | 158.0 | 0.79 | T | -126.6 | -21.8 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | LYS | A:397 | A:355 | 155.0 | 0.775 | S | -144.9 | 21.0 | 155.0 | 0.775 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | LYS | A:397 | A:355 | 167.0 | 0.835 | T | -124.3 | -14.2 | 167.0 | 0.835 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | LYS | A:355 | A:355 | 143.0 | 0.715 | T | -143.2 | 11.6 | 143.0 | 0.715 | 0.0 |
HOH |
7.880 |
N |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | LYS | A:355 | A:355 | 145.0 | 0.725 | T | -145.6 | 11.1 | 145.0 | 0.725 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 153.0 | 0.765 | T | -129.9 | -35.5 | 153.0 | 0.765 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 152.0 | 0.76 | T | -118.8 | -40.1 | 152.0 | 0.76 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 153.0 | 0.765 | T | -117.4 | -44.6 | 153.0 | 0.765 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 146.0 | 0.73 | T | -109.8 | -21.1 | 146.0 | 0.73 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 144.0 | 0.72 | T | -123.6 | -44.6 | 144.0 | 0.72 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 130.0 | 0.65 | T | -111.1 | -34.5 | 130.0 | 0.65 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 150.0 | 0.75 | T | -116.4 | -37.9 | 150.0 | 0.75 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 142.0 | 0.71 | T | -115.4 | -3.7 | 142.0 | 0.71 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 122.0 | 0.61 | T | -119.4 | -27.0 | 122.0 | 0.61 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 123.0 | 0.615 | S | -127.2 | -41.1 | 123.0 | 0.615 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 123.0 | 0.615 | T | -128.1 | -32.4 | 123.0 | 0.615 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 151.0 | 0.755 | T | -130.3 | -44.7 | 151.0 | 0.755 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 133.0 | 0.665 | T | -119.7 | -34.9 | 133.0 | 0.665 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 144.0 | 0.72 | T | -100.7 | -41.4 | 144.0 | 0.72 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 123.0 | 0.615 | G | -128.7 | 32.0 | 123.0 | 0.615 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 138.0 | 0.69 | T | -105.4 | -52.3 | 138.0 | 0.69 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:355 | A:355 | 141.0 | 0.705 | T | -115.3 | 10.4 | 141.0 | 0.705 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | LYS | A:355 | A:355 | 152.0 | 0.76 | T | -125.6 | -52.7 | 152.0 | 0.76 | 0.0 |
HOH |
7.483 |
N |
O |
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| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | LYS | A:355 | A:355 | 165.0 | 0.825 | T | -128.5 | -17.8 | 165.0 | 0.825 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:354 | A:354 | 130.0 | 0.65 | T | -129.3 | -41.6 | 130.0 | 0.65 | 0.0 |
HOH |
3.978 |
NZ |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:354 | A:354 | 139.0 | 0.695 | T | -121.7 | -40.6 | 139.0 | 0.695 | 0.0 |
HOH |
4.133 |
O |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:354 | A:354 | 130.0 | 0.65 | T | -131.3 | -27.6 | 130.0 | 0.65 | 0.0 |
UNL UNL UNL UNL HOH |
4.130 7.108 7.173 8.721 2.527 |
CA N N C NZ |
C17 O O O O |
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| LYS | E:354 | N:354 | 130.0 | 0.65 | T | -131.1 | -26.7 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | LYS | A:354 | A:354 | 131.0 | 0.655 | T | -122.0 | -31.0 | 131.0 | 0.655 | 0.0 |
HOH |
2.517 |
NZ |
O |
||
| LYS | E:354 | N:354 | 135.0 | 0.675 | T | -121.4 | -30.5 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | LYS | A:354 | A:354 | 135.0 | 0.675 | T | -126.6 | -33.4 | 135.0 | 0.675 | 0.0 |
UNL HOH |
8.372 3.378 |
N NZ |
O1 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | LYS | A:354 | A:354 | 129.0 | 0.645 | T | -123.3 | -33.2 | 129.0 | 0.645 | 0.0 |
UNL UNL HOH |
3.698 6.911 2.510 |
O O NZ |
C2 C2 O |
||
| LYS | E:354 | N:354 | 130.0 | 0.65 | T | -121.5 | -32.7 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 149.0 | 0.745 | T | -125.2 | -42.8 | 149.0 | 0.745 | 0.0 |
HOH |
5.117 |
N |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 149.0 | 0.745 | T | -135.9 | -38.9 | 149.0 | 0.745 | 0.0 |
HOH |
2.713 |
O |
O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 139.0 | 0.695 | T | -116.2 | -38.9 | 139.0 | 0.695 | 0.0 |
HOH |
5.157 |
C |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | LYS | A:354 | A:354 | 141.0 | 0.705 | T | -132.2 | -32.5 | 141.0 | 0.705 | 0.0 |
UNL |
8.437 |
N |
N1 |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 138.0 | 0.69 | T | -125.5 | -49.4 | 138.0 | 0.69 | 0.0 |
HOH |
4.569 |
CB |
O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 149.0 | 0.745 | T | -126.2 | -35.5 | 149.0 | 0.745 | 0.0 | ||||||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:354 | A:354 | 142.0 | 0.71 | T | -121.9 | -37.9 | 142.0 | 0.71 | 0.0 |
HOH |
5.246 |
C |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | LYS | A:397 | A:397 | 132.0 | 0.66 | T | -126.4 | -47.3 | |