Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 235452 | . | C | A | CCDS3853.1:NM_004168.2:c.1258Cag>Aag_NP_004159.2:p.420Q>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLN | A:388 | A:420 | 34.0 | 0.189 | E | -78.3 | 124.4 | 34.0 | 0.189 | 0.0 |
HOH |
5.037 |
NE2 |
O |
||
| GLN | C:388 | C:420 | 26.0 | 0.144 | E | -78.5 | 122.5 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLN | A:420 | A:378 | 45.0 | 0.25 | E | -87.5 | 136.8 | 45.0 | 0.25 | 0.0 |
HOH |
8.916 |
NE2 |
O |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLN | A:420 | A:378 | 41.0 | 0.228 | E | -72.5 | 134.0 | 41.0 | 0.228 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:378 | A:378 | 38.0 | 0.211 | E | -72.2 | 137.3 | 38.0 | 0.211 | 0.0 |
HOH |
2.413 |
N |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:378 | A:378 | 40.0 | 0.222 | E | -73.2 | 135.9 | 40.0 | 0.222 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 37.0 | 0.206 | E | -97.4 | 129.6 | 37.0 | 0.206 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 43.0 | 0.239 | E | -72.9 | 126.6 | 43.0 | 0.239 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 41.0 | 0.228 | E | -104.3 | 134.8 | 41.0 | 0.228 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 42.0 | 0.233 | E | -79.4 | 130.0 | 42.0 | 0.233 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 37.0 | 0.206 | E | -74.1 | 135.3 | 37.0 | 0.206 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 39.0 | 0.217 | E | -69.9 | 136.1 | 39.0 | 0.217 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 35.0 | 0.194 | E | -75.1 | 135.2 | 35.0 | 0.194 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 43.0 | 0.239 | E | -77.0 | 133.4 | 43.0 | 0.239 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 38.0 | 0.211 | E | -70.4 | 137.2 | 38.0 | 0.211 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 43.0 | 0.239 | E | -85.0 | 135.6 | 43.0 | 0.239 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 46.0 | 0.256 | E | -82.0 | 137.7 | 46.0 | 0.256 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 43.0 | 0.239 | E | -85.5 | 128.3 | 43.0 | 0.239 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 54.0 | 0.3 | E | -75.3 | 133.6 | 54.0 | 0.3 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 39.0 | 0.217 | E | -89.1 | 129.9 | 39.0 | 0.217 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 38.0 | 0.211 | E | -77.0 | 121.9 | 38.0 | 0.211 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 39.0 | 0.217 | E | -83.0 | 132.9 | 39.0 | 0.217 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:378 | A:378 | 38.0 | 0.211 | E | -71.9 | 137.5 | 38.0 | 0.211 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:378 | A:378 | 40.0 | 0.222 | E | -76.6 | 134.4 | 40.0 | 0.222 | 0.0 |
HOH |
3.626 |
OE1 |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:378 | A:378 | 39.0 | 0.217 | E | -81.0 | 129.2 | 39.0 | 0.217 | 0.0 |
HOH |
3.193 |
CB |
O |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:377 | A:377 | 30.0 | 0.167 | E | -79.9 | 129.1 | 30.0 | 0.167 | 0.0 |
HOH |
2.934 |
OE1 |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:377 | A:377 | 25.0 | 0.139 | E | -84.9 | 132.0 | 25.0 | 0.139 | 0.0 |
HOH |
2.725 |
OE1 |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:377 | A:377 | 31.0 | 0.172 | E | -79.6 | 136.3 | 31.0 | 0.172 | 0.0 |
UNL HOH |
7.257 2.574 |
CD OE1 |
O1 O |
||
| GLN | E:377 | N:377 | 33.0 | 0.183 | E | -79.7 | 133.1 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:377 | A:377 | 28.0 | 0.156 | E | -81.1 | 136.2 | 28.0 | 0.156 | 0.0 |
HOH |
2.912 |
OE1 |
O |
||
| GLN | E:377 | N:377 | 29.0 | 0.161 | E | -80.1 | 136.9 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:377 | A:377 | 30.0 | 0.167 | E | -84.6 | 135.4 | 30.0 | 0.167 | 0.0 |
HOH |
3.335 |
CB |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLN | A:377 | A:377 | 33.0 | 0.183 | E | -77.5 | 134.2 | 33.0 | 0.183 | 0.0 |
HOH |
2.742 |
OE1 |
O |
||
| GLN | E:377 | N:377 | 32.0 | 0.178 | E | -79.5 | 132.8 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 29.0 | 0.161 | E | -70.3 | 136.3 | 29.0 | 0.161 | 0.0 |
UNL HOH |
7.847 3.594 |
OE1 CB |
O2 O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 33.0 | 0.183 | E | -72.5 | 128.1 | 33.0 | 0.183 | 0.0 |
BCT UNL UNL UNL HOH |
7.634 7.437 8.770 3.384 4.594 |
CD O OE1 CB OE1 |
O2 N1 O3 N3 O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 32.0 | 0.178 | E | -76.5 | 130.5 | 32.0 | 0.178 | 0.0 |
HOH |
2.750 |
OE1 |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLN | A:377 | A:377 | 28.0 | 0.156 | E | -76.2 | 127.5 | 28.0 | 0.156 | 0.0 |
UNL HOH |
7.390 3.421 |
CG CB |
O4 O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 27.0 | 0.15 | E | -89.3 | 127.0 | 27.0 | 0.15 | 0.0 |
UNL HOH |
9.867 3.318 |
NE2 CB |
O O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 27.0 | 0.15 | E | -75.0 | 128.2 | 27.0 | 0.15 | 0.0 |
UNL HOH |
4.579 3.687 |
NE2 CB |
O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:377 | A:377 | 29.0 | 0.161 | E | -76.5 | 126.2 | 29.0 | 0.161 | 0.0 |
UNL HOH |
7.853 3.277 |
OE1 OE1 |
C O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLN | A:420 | A:420 | 30.0 | 0.167 | E | -76.4 | 130.2 | |