Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 236544 | . | T | A | CCDS3853.1:NM_004168.2:c.1262gTc>gAc_NP_004159.2:p.421V>D | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | VAL | A:389 | A:421 | 0.0 | 0.0 | E | -63.3 | 140.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.440 |
N |
O |
||
| VAL | C:389 | C:421 | 0.0 | 0.0 | E | -63.9 | 137.5 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | VAL | A:421 | A:379 | 0.0 | 0.0 | E | -74.2 | 141.6 | 0.0 | 0.0 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | VAL | A:421 | A:379 | 0.0 | 0.0 | E | -84.0 | 133.9 | 0.0 | 0.0 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -73.9 | 139.1 | 1.0 | 0.006 | 0.0 |
HOH |
3.282 |
CG1 |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -72.6 | 139.7 | 1.0 | 0.006 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 0.0 | 0.0 | E | -64.7 | 126.1 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -71.1 | 129.8 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -72.6 | 127.4 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 2.0 | 0.013 | E | -67.5 | 132.2 | 2.0 | 0.013 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -75.6 | 133.1 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -73.7 | 135.0 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -75.9 | 132.2 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -73.3 | 133.0 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 2.0 | 0.013 | E | -76.1 | 129.1 | 2.0 | 0.013 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 2.0 | 0.013 | E | -75.1 | 127.4 | 2.0 | 0.013 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 2.0 | 0.013 | E | -74.0 | 137.5 | 2.0 | 0.013 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -67.7 | 130.7 | 1.0 | 0.006 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -73.5 | 130.7 | 1.0 | 0.006 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -65.3 | 135.7 | 1.0 | 0.006 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 0.0 | 0.0 | E | -65.5 | 130.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -69.2 | 133.0 | 1.0 | 0.006 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | VAL | A:379 | A:379 | 2.0 | 0.013 | E | -79.8 | 126.2 | 2.0 | 0.013 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -72.9 | 131.8 | 1.0 | 0.006 | 0.0 |
HOH |
3.295 |
CG1 |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | VAL | A:379 | A:379 | 1.0 | 0.006 | E | -71.8 | 133.3 | 1.0 | 0.006 | 0.0 |
HOH |
3.923 |
N |
O |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -63.9 | 139.4 | 2.0 | 0.013 | 0.0 |
HOH |
3.495 |
CG1 |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -69.5 | 132.9 | 2.0 | 0.013 | 0.0 |
HOH |
4.466 |
N |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | VAL | A:378 | A:378 | 1.0 | 0.006 | E | -70.7 | 136.5 | 1.0 | 0.006 | 0.0 |
HOH |
3.461 |
CG1 |
O |
||
| VAL | E:378 | N:378 | 1.0 | 0.006 | E | -66.8 | 138.2 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | VAL | A:378 | A:378 | 1.0 | 0.006 | E | -73.6 | 141.3 | 1.0 | 0.006 | 0.0 |
HOH |
3.397 |
CG1 |
O |
||
| VAL | E:378 | N:378 | 2.0 | 0.013 | E | -73.1 | 139.9 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | VAL | A:378 | A:378 | 3.0 | 0.019 | E | -70.7 | 131.5 | 3.0 | 0.019 | 0.0 |
HOH |
3.778 |
N |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -70.7 | 139.1 | 2.0 | 0.013 | 0.0 |
HOH |
3.832 |
CG1 |
O |
||
| VAL | E:378 | N:378 | 1.0 | 0.006 | E | -69.5 | 139.4 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -77.5 | 143.6 | 2.0 | 0.013 | 0.0 |
HOH |
3.660 |
CG1 |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 3.0 | 0.019 | E | -67.4 | 136.8 | 3.0 | 0.019 | 0.0 |
UNL UNL HOH |
9.584 4.255 3.672 |
C N CG1 |
N1 N3 O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 1.0 | 0.006 | E | -66.5 | 141.7 | 1.0 | 0.006 | 0.0 |
HOH |
3.176 |
CG1 |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -63.7 | 140.1 | 2.0 | 0.013 | 0.0 |
HOH |
4.452 |
N |
O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 2.0 | 0.013 | E | -65.0 | 134.7 | 2.0 | 0.013 | 0.0 |
HOH |
4.375 |
N |
O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 3.0 | 0.019 | E | -65.6 | 134.6 | 3.0 | 0.019 | 0.0 |
UNL HOH |
9.009 3.476 |
N CG1 |
O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | VAL | A:378 | A:378 | 1.0 | 0.006 | E | -62.1 | 137.3 | 1.0 | 0.006 | 0.0 |
HOH |
3.288 |
CG1 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | VAL | A:421 | A:421 | 1.0 | 0.006 | E | -66.6 | 137.5 | |