Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 236639 | . | G | A | CCDS3853.1:NM_004168.2:c.1357Ggg>Agg_NP_004159.2:p.453G>R | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLY | A:421 | A:453 | 9.0 | 0.12 | T | -69.0 | 147.4 | 9.0 | 0.12 | 0.0 |
FAD OAA HOH |
4.886 3.926 5.501 |
C CA N |
O2 O5 O |
||
GLY | C:421 | C:453 | 27.0 | 0.36 | T | -68.4 | 149.7 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLY | A:453 | A:411 | 1.0 | 0.013 | T | -63.6 | 144.2 | 1.0 | 0.013 | 0.0 |
FAD |
5.045 |
C |
O2 |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLY | A:453 | A:411 | 0.0 | 0.0 | T | -50.3 | 128.7 | 0.0 | 0.0 | 0.0 |
FAD |
5.275 |
C |
O2 |
||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLY | A:411 | A:411 | 2.0 | 0.027 | T | -52.7 | 138.5 | 2.0 | 0.027 | 0.0 |
FAD HOH |
4.751 3.367 |
C C |
O2 O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLY | A:411 | A:411 | 2.0 | 0.027 | T | -51.0 | 137.0 | 2.0 | 0.027 | 0.0 |
FAD 3NP |
4.708 3.875 |
C CA |
O2 C2 |
||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -64.2 | 129.1 | 1.0 | 0.013 | 0.0 |
FAD MLI |
5.208 4.217 |
C C |
O2 O8 |
||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -56.5 | 143.8 | 0.0 | 0.0 | 0.0 |
FAD MLI |
5.367 3.929 |
C CA |
O2 O7 |
||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -57.6 | 133.2 | 0.0 | 0.0 | 0.0 |
FAD MLI |
5.117 4.160 |
C CA |
O2 O9 |
||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -58.2 | 133.3 | 1.0 | 0.013 | 0.0 |
FAD |
5.724 |
C |
O2 |
||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -62.0 | 139.3 | 0.0 | 0.0 | 0.0 |
FAD MLI |
5.289 4.322 |
C CA |
O2 O9 |
||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -62.1 | 116.0 | 1.0 | 0.013 | 0.0 |
FAD MLI |
5.882 4.354 |
C C |
O2 O9 |
||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -57.8 | 135.1 | 1.0 | 0.013 | 0.0 |
FAD |
5.778 |
C |
O2 |
||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -57.9 | 132.7 | 1.0 | 0.013 | 0.0 |
FAD |
6.034 |
C |
O2 |
||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 3.0 | 0.04 | T | -57.4 | 126.6 | 3.0 | 0.04 | 0.0 |
FAD |
5.918 |
C |
O2 |
||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -57.5 | 137.6 | 1.0 | 0.013 | 0.0 |
FAD MLI |
5.518 5.305 |
C C |
O2 O6 |
||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -58.3 | 129.2 | 1.0 | 0.013 | 0.0 |
FAD MLI |
5.415 4.390 |
C C |
O2 O7 |
||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -59.8 | 139.7 | 1.0 | 0.013 | 0.0 |
FAD MLI |
5.072 4.145 |
C CA |
O2 O8 |
||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -58.4 | 133.5 | 0.0 | 0.0 | 0.0 |
FAD |
5.840 |
C |
O2 |
||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 2.0 | 0.027 | T | -59.5 | 129.2 | 2.0 | 0.027 | 0.0 |
FAD MLI |
5.489 4.551 |
C CA |
O2 O9 |
||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -59.9 | 137.8 | 1.0 | 0.013 | 0.0 |
FAD |
5.211 |
C |
O2 |
||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -66.7 | 134.7 | 0.0 | 0.0 | 0.0 |
FAD HOH |
4.927 4.151 |
C CA |
O2 O |
||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:411 | A:411 | 0.0 | 0.0 | T | -65.1 | 113.5 | 0.0 | 0.0 | 0.0 |
FAD |
5.786 |
C |
O2 |
||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -51.7 | 133.0 | 1.0 | 0.013 | 0.0 |
FAD OAA HOH |
5.266 3.626 6.020 |
C CA N |
O2 O1 O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLY | A:411 | A:411 | 1.0 | 0.013 | T | -64.4 | 131.9 | 1.0 | 0.013 | 0.0 |
FAD OAA |
5.309 3.983 |
C C |
O2 O1 |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:410 | A:410 | 0.0 | 0.0 | T | -57.4 | 146.9 | 0.0 | 0.0 | 0.0 |
FAD TEO HOH |
4.876 3.332 2.692 |
C CA O |
O2 O4B O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:410 | A:410 | 0.0 | 0.0 | T | -53.2 | 142.4 | 0.0 | 0.0 | 0.0 |
FAD 3NP HOH |
4.900 3.967 2.930 |
C CA N |
O2 C3 O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -49.1 | 138.5 | 1.0 | 0.013 | 0.0 |
FAD Y3P UNL HOH |
4.829 3.304 9.660 2.664 |
C CA N O |
O2 O5 OAA O |
||
GLY | E:410 | N:410 | 1.0 | 0.013 | T | -52.1 | 139.4 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -54.3 | 145.0 | 1.0 | 0.013 | 0.0 |
FAD TEO HOH |
4.904 3.324 2.777 |
C CA O |
O2 O4A O |
||
GLY | E:410 | N:410 | 1.0 | 0.013 | T | -55.7 | 146.3 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -53.0 | 133.2 | 1.0 | 0.013 | 0.0 |
FAD MLI HOH |
4.969 3.841 4.247 |
C CA N |
O2 O9 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -52.7 | 145.0 | 1.0 | 0.013 | 0.0 |
FAD OAA HOH |
4.885 3.242 2.723 |
C CA O |
O2 O2 O |
||
GLY | E:410 | N:410 | 1.0 | 0.013 | T | -51.3 | 145.1 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -50.2 | 135.3 | 1.0 | 0.013 | 0.0 |
FAD OAA HOH |
5.126 3.573 2.304 |
C C O |
O2 O2 O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -59.4 | 147.0 | 1.0 | 0.013 | 0.0 |
FAD OAA HOH |
4.955 3.356 2.431 |
C CA O |
O2 O2 O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -56.2 | 147.1 | 1.0 | 0.013 | 0.0 |
FAD Y3P HOH |
4.855 3.166 2.641 |
C CA O |
O2 O5 O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLY | A:410 | A:410 | 0.0 | 0.0 | T | -55.5 | 144.6 | 0.0 | 0.0 | 0.0 |
FAD OAA HOH |
4.989 3.603 5.832 |
C CA N |
O2 O2 O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -61.5 | 144.7 | 1.0 | 0.013 | 0.0 |
FAD OAA HOH |
4.993 3.491 6.724 |
C CA O |
O2 O2 O |
||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 1.0 | 0.013 | T | -59.8 | 145.2 | 1.0 | 0.013 | 0.0 |
FAD OAA UNL HOH |
4.914 3.555 2.321 2.881 |
C CA O N |
O2 O2 O O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:410 | A:410 | 0.0 | 0.0 | T | -54.2 | 143.8 | 0.0 | 0.0 | 0.0 |
FAD OAA HOH |
4.966 3.198 2.486 |
C CA O |
O2 O2 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLY | A:453 | A:453 | 0.0 | 0.0 | T | -57.2 | 146.0 |