Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 236676 | . | G | A | CCDS3853.1:NM_004168.2:c.1394cGg>cAg_NP_004159.2:p.465R>Q | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ARG | A:433 | A:465 | 64.0 | 0.284 | H | -66.5 | -37.7 | 64.0 | 0.284 | 0.0 |
HOH |
5.838 |
NH1 |
O |
||
ARG | C:433 | C:465 | 65.0 | 0.289 | H | -67.1 | -34.6 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ARG | A:465 | A:423 | 53.0 | 0.236 | H | -55.4 | -46.1 | 53.0 | 0.236 | 0.0 |
HOH |
5.707 |
NE |
O |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ARG | A:465 | A:423 | 50.0 | 0.222 | H | -65.2 | -29.9 | 50.0 | 0.222 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:423 | A:423 | 61.0 | 0.271 | H | -63.4 | -43.6 | 61.0 | 0.271 | 0.0 |
HOH |
3.092 |
CD |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:423 | A:423 | 60.0 | 0.267 | H | -71.4 | -42.6 | 60.0 | 0.267 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 61.0 | 0.271 | H | -54.5 | -43.7 | 61.0 | 0.271 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 66.0 | 0.293 | H | -55.6 | -39.7 | 66.0 | 0.293 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 65.0 | 0.289 | H | -55.1 | -44.0 | 65.0 | 0.289 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 51.0 | 0.227 | H | -66.3 | -41.5 | 51.0 | 0.227 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 57.0 | 0.253 | H | -59.1 | -48.3 | 57.0 | 0.253 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 61.0 | 0.271 | H | -63.1 | -40.0 | 61.0 | 0.271 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 60.0 | 0.267 | H | -60.1 | -36.6 | 60.0 | 0.267 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 63.0 | 0.28 | H | -68.2 | -37.4 | 63.0 | 0.28 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 69.0 | 0.307 | H | -65.1 | -41.4 | 69.0 | 0.307 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 49.0 | 0.218 | H | -66.9 | -38.0 | 49.0 | 0.218 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 53.0 | 0.236 | H | -63.1 | -40.2 | 53.0 | 0.236 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 57.0 | 0.253 | H | -61.7 | -42.0 | 57.0 | 0.253 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 55.0 | 0.244 | H | -67.1 | -36.8 | 55.0 | 0.244 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 50.0 | 0.222 | H | -59.3 | -41.2 | 50.0 | 0.222 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 71.0 | 0.316 | H | -33.0 | -52.3 | 71.0 | 0.316 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 65.0 | 0.289 | H | -61.0 | -43.2 | 65.0 | 0.289 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:423 | A:423 | 65.0 | 0.289 | H | -67.5 | -41.1 | 65.0 | 0.289 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:423 | A:423 | 64.0 | 0.284 | H | -63.0 | -34.6 | 64.0 | 0.284 | 0.0 |
HOH |
2.875 |
NH2 |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:423 | A:423 | 59.0 | 0.262 | H | -63.3 | -44.6 | 59.0 | 0.262 | 0.0 |
HOH |
6.155 |
O |
O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:422 | A:422 | 95.0 | 0.422 | H | -69.9 | -41.7 | 95.0 | 0.422 | 0.0 |
UNL HOH |
9.748 2.218 |
NH2 NE |
O1 O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:422 | A:422 | 86.0 | 0.382 | H | -73.7 | -42.5 | 86.0 | 0.382 | 0.0 |
HOH |
2.396 |
NE |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:422 | A:422 | 89.0 | 0.396 | H | -61.6 | -41.2 | 89.0 | 0.396 | 0.0 |
UNL UNL UNL UNL HOH |
6.009 3.831 4.523 9.017 2.316 |
O NH1 NE O NE |
C1 O3 O O O |
||
ARG | E:422 | N:422 | 90.0 | 0.4 | H | -62.0 | -41.2 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:422 | A:422 | 92.0 | 0.409 | H | -67.4 | -39.7 | 92.0 | 0.409 | 0.0 |
HOH |
2.368 |
NE |
O |
||
ARG | E:422 | N:422 | 89.0 | 0.396 | H | -67.9 | -39.6 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:422 | A:422 | 73.0 | 0.324 | H | -70.5 | -40.0 | 73.0 | 0.324 | 0.0 |
UNL HOH |
9.927 3.512 |
NH2 CB |
O1 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ARG | A:422 | A:422 | 86.0 | 0.382 | H | -64.7 | -42.9 | 86.0 | 0.382 | 0.0 |
UNL HOH |
9.271 2.583 |
NH2 NE |
C2 O |
||
ARG | E:422 | N:422 | 84.0 | 0.373 | H | -64.7 | -43.2 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 89.0 | 0.396 | H | -66.0 | -32.8 | 89.0 | 0.396 | 0.0 |
UNL UNL UNL HOH |
6.484 4.664 2.700 3.059 |
O NE NE NH1 |
O1 O O O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 87.0 | 0.387 | H | -71.2 | -33.2 | 87.0 | 0.387 | 0.0 |
BCT UNL UNL HOH |
5.895 4.846 3.649 2.758 |
O CG NH1 NE |
O1 N1 C O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 91.0 | 0.404 | H | -67.7 | -38.9 | 91.0 | 0.404 | 0.0 |
UNL HOH |
2.880 3.186 |
NE NH1 |
O O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ARG | A:422 | A:422 | 81.0 | 0.36 | H | -61.4 | -41.2 | 81.0 | 0.36 | 0.0 |
HOH |
2.327 |
NH1 |
O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 87.0 | 0.387 | H | -61.9 | -36.9 | 87.0 | 0.387 | 0.0 |
UNL HOH |
2.322 3.499 |
NH1 CB |
O O |
||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 90.0 | 0.4 | H | -69.0 | -32.0 | 90.0 | 0.4 | 0.0 |
HOH |
3.514 |
NE |
O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:422 | A:422 | 89.0 | 0.396 | H | -63.9 | -42.1 | 89.0 | 0.396 | 0.0 |
UNL UNL HOH |
6.457 2.827 3.227 |
O NE NH1 |
O O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ARG | A:465 | A:465 | 72.0 | 0.32 | H | -66.7 | -41.4 |