Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 236678 | . | G | A | CCDS3853.1:NM_004168.2:c.1396Gca>Aca_NP_004159.2:p.466A>T | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ALA | A:434 | A:466 | 2.0 | 0.017 | H | -65.8 | -37.4 | 2.0 | 0.017 | 0.0 |
HOH |
4.180 |
O |
O |
||
| ALA | C:434 | C:466 | 3.0 | 0.026 | H | -67.3 | -35.3 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ALA | A:466 | A:424 | 1.0 | 0.009 | H | -60.6 | -48.9 | 1.0 | 0.009 | 0.0 |
HOH |
5.541 |
CB |
O |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:466 | A:424 | 2.0 | 0.017 | H | -68.6 | -44.0 | 2.0 | 0.017 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -58.6 | -39.6 | 1.0 | 0.009 | 0.0 |
HOH |
3.876 |
N |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -56.3 | -45.1 | 1.0 | 0.009 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 3.0 | 0.026 | H | -59.1 | -44.8 | 3.0 | 0.026 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 3.0 | 0.026 | H | -60.9 | -51.9 | 3.0 | 0.026 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 3.0 | 0.026 | H | -62.2 | -45.3 | 3.0 | 0.026 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 3.0 | 0.026 | H | -62.4 | -42.5 | 3.0 | 0.026 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 0.0 | 0.0 | H | -57.7 | -50.5 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -61.2 | -45.0 | 1.0 | 0.009 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -59.6 | -51.1 | 1.0 | 0.009 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -67.1 | -39.6 | 1.0 | 0.009 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -63.7 | -35.9 | 1.0 | 0.009 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 2.0 | 0.017 | H | -66.6 | -34.2 | 2.0 | 0.017 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -63.1 | -39.1 | 1.0 | 0.009 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -63.3 | -39.3 | 1.0 | 0.009 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 2.0 | 0.017 | H | -63.6 | -40.9 | 2.0 | 0.017 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -62.0 | -44.4 | 1.0 | 0.009 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 3.0 | 0.026 | H | -57.9 | -48.0 | 3.0 | 0.026 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 2.0 | 0.017 | H | -62.3 | -47.7 | 2.0 | 0.017 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:424 | A:424 | 0.0 | 0.0 | H | -66.1 | -37.2 | 0.0 | 0.0 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:424 | A:424 | 2.0 | 0.017 | H | -63.1 | -50.6 | 2.0 | 0.017 | 0.0 |
HOH |
6.573 |
N |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:424 | A:424 | 1.0 | 0.009 | H | -56.7 | -47.1 | 1.0 | 0.009 | 0.0 |
HOH |
8.272 |
N |
O |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:423 | A:423 | 2.0 | 0.017 | H | -55.8 | -43.2 | 2.0 | 0.017 | 0.0 |
HOH |
3.514 |
N |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:423 | A:423 | 2.0 | 0.017 | H | -50.2 | -55.1 | 2.0 | 0.017 | 0.0 |
HOH |
3.390 |
N |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:423 | A:423 | 3.0 | 0.026 | H | -64.2 | -42.2 | 3.0 | 0.026 | 0.0 |
UNL UNL UNL HOH |
3.933 7.077 7.720 3.528 |
O CA O CB |
C1 O1 O O |
||
| ALA | E:423 | N:423 | 4.0 | 0.035 | H | -64.0 | -43.7 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:423 | A:423 | 3.0 | 0.026 | H | -62.0 | -39.4 | 3.0 | 0.026 | 0.0 |
HOH |
3.630 |
N |
O |
||
| ALA | E:423 | N:423 | 3.0 | 0.026 | H | -61.9 | -39.0 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:423 | A:423 | 2.0 | 0.017 | H | -55.7 | -40.1 | 2.0 | 0.017 | 0.0 |
HOH |
3.319 |
N |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ALA | A:423 | A:423 | 3.0 | 0.026 | H | -61.1 | -41.2 | 3.0 | 0.026 | 0.0 |
HOH |
3.649 |
N |
O |
||
| ALA | E:423 | N:423 | 3.0 | 0.026 | H | -60.6 | -41.1 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 1.0 | 0.009 | H | -62.5 | -41.2 | 1.0 | 0.009 | 0.0 |
UNL UNL UNL HOH |
4.578 7.391 7.452 3.347 |
O N N N |
O1 O O O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 2.0 | 0.017 | H | -62.9 | -37.0 | 2.0 | 0.017 | 0.0 |
BCT UNL UNL UNL HOH |
4.101 7.774 9.740 6.724 3.403 |
O N O CA CB |
O1 N1 N3 O O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 0.0 | 0.0 | H | -54.4 | -46.3 | 0.0 | 0.0 | 0.0 |
UNL HOH |
7.503 3.583 |
N CB |
O O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ALA | A:423 | A:423 | 3.0 | 0.026 | H | -61.3 | -41.2 | 3.0 | 0.026 | 0.0 |
UNL HOH |
3.759 3.548 |
O N |
O4 O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 2.0 | 0.017 | H | -65.4 | -40.2 | 2.0 | 0.017 | 0.0 |
UNL UNL HOH |
5.450 6.557 3.759 |
O N N |
O O O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 1.0 | 0.009 | H | -62.7 | -40.0 | 1.0 | 0.009 | 0.0 |
UNL HOH |
8.686 6.640 |
O N |
O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:423 | A:423 | 1.0 | 0.009 | H | -54.2 | -43.5 | 1.0 | 0.009 | 0.0 |
UNL UNL HOH |
4.280 7.436 3.586 |
O N CB |
O O O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ALA | A:466 | A:466 | 3.0 | 0.026 | H | -60.6 | -39.0 | |