Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 236696 | . | G | A | CCDS3853.1:NM_004168.2:c.1414Gaa>Aaa_NP_004159.2:p.472E>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLU | A:440 | A:472 | 58.0 | 0.305 | H | -77.0 | -20.0 | 58.0 | 0.305 | 0.0 |
HOH |
3.505 |
OE2 |
O |
||
GLU | C:440 | C:472 | 67.0 | 0.353 | H | -64.9 | -41.6 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ALA | A:472 | A:430 | 17.0 | 0.148 | H | -48.0 | -53.6 | 17.0 | 0.148 | 0.0 |
HOH |
9.516 |
N |
O |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:472 | A:430 | 20.0 | 0.174 | H | -49.8 | -51.7 | 20.0 | 0.174 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:430 | A:430 | 19.0 | 0.165 | H | -63.9 | -30.3 | 19.0 | 0.165 | 0.0 |
HOH |
5.800 |
CB |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:430 | A:430 | 18.0 | 0.157 | H | -65.9 | -29.1 | 18.0 | 0.157 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 16.0 | 0.139 | H | -51.8 | -31.8 | 16.0 | 0.139 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 8.0 | 0.07 | H | -56.6 | -13.1 | 8.0 | 0.07 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 16.0 | 0.139 | H | -50.8 | -32.4 | 16.0 | 0.139 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 18.0 | 0.157 | H | -54.1 | -54.2 | 18.0 | 0.157 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 17.0 | 0.148 | H | -62.1 | -37.2 | 17.0 | 0.148 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 21.0 | 0.183 | H | -68.2 | -22.4 | 21.0 | 0.183 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 13.0 | 0.113 | H | -58.8 | -41.2 | 13.0 | 0.113 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 13.0 | 0.113 | H | -75.6 | -52.7 | 13.0 | 0.113 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 18.0 | 0.157 | H | -64.2 | -28.0 | 18.0 | 0.157 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 20.0 | 0.174 | H | -61.2 | -26.2 | 20.0 | 0.174 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 20.0 | 0.174 | H | -58.8 | -24.1 | 20.0 | 0.174 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 18.0 | 0.157 | H | -60.4 | -17.5 | 18.0 | 0.157 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 13.0 | 0.113 | H | -59.1 | -32.6 | 13.0 | 0.113 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 19.0 | 0.165 | H | -60.3 | -34.9 | 19.0 | 0.165 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 16.0 | 0.139 | H | -47.8 | -29.0 | 16.0 | 0.139 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 23.0 | 0.2 | H | -58.6 | -15.5 | 23.0 | 0.2 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:430 | A:430 | 22.0 | 0.191 | H | -67.3 | -18.3 | 22.0 | 0.191 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:430 | A:430 | 17.0 | 0.148 | H | -50.3 | -36.5 | 17.0 | 0.148 | 0.0 |
HOH |
5.796 |
CB |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:430 | A:430 | 18.0 | 0.157 | H | -45.9 | -45.8 | 18.0 | 0.157 | 0.0 |
HOH |
6.126 |
CB |
O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:429 | A:429 | 41.0 | 0.357 | H | -66.5 | -29.0 | 41.0 | 0.357 | 0.0 |
UNL HOH |
3.357 2.858 |
O O |
O1 O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:429 | A:429 | 33.0 | 0.287 | H | -57.8 | -51.4 | 33.0 | 0.287 | 0.0 |
HOH |
3.467 |
CB |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:429 | A:429 | 27.0 | 0.235 | H | -65.3 | -29.4 | 27.0 | 0.235 | 0.0 |
UNL UNL UNL UNL UNL HOH |
8.190 9.592 7.242 2.569 7.015 5.945 |
N CB O O C CB |
O1 O2 O O O O |
||
ALA | E:429 | N:429 | 41.0 | 0.357 | H | -65.3 | -29.9 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:429 | A:429 | 43.0 | 0.374 | H | -62.4 | -25.5 | 43.0 | 0.374 | 0.0 |
HOH |
2.672 |
O |
O |
||
ALA | E:429 | N:429 | 42.0 | 0.365 | H | -62.8 | -25.4 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:429 | A:429 | 42.0 | 0.365 | H | -55.4 | -34.3 | 42.0 | 0.365 | 0.0 |
UNL HOH |
3.243 3.099 |
O O |
O1 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ALA | A:429 | A:429 | 37.0 | 0.322 | H | -66.7 | -24.6 | 37.0 | 0.322 | 0.0 |
UNL HOH |
4.574 2.470 |
CB O |
C2 O |
||
ALA | E:429 | N:429 | 40.0 | 0.348 | H | -67.2 | -24.1 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 43.0 | 0.374 | H | -62.2 | -42.1 | 43.0 | 0.374 | 0.0 |
UNL UNL UNL HOH |
8.355 6.444 7.914 3.247 |
N CB CB CB |
O1 O O O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 44.0 | 0.383 | H | -66.9 | -29.8 | 44.0 | 0.383 | 0.0 |
BCT UNL UNL HOH |
8.133 5.583 9.846 3.425 |
N CB N CB |
O1 N3 N1 O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 43.0 | 0.374 | H | -67.6 | -35.6 | 43.0 | 0.374 | 0.0 |
UNL HOH |
8.177 3.872 |
CB CB |
O O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ALA | A:429 | A:429 | 41.0 | 0.357 | H | -66.9 | -33.1 | 41.0 | 0.357 | 0.0 |
UNL HOH |
7.717 2.333 |
N O |
O4 O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 43.0 | 0.374 | H | -66.0 | -34.6 | 43.0 | 0.374 | 0.0 |
UNL UNL HOH |
9.042 6.212 3.419 |
N CB CB |
O O O |
||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 45.0 | 0.391 | H | -63.2 | -30.2 | 45.0 | 0.391 | 0.0 |
UNL HOH |
6.515 6.849 |
N CB |
O O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:429 | A:429 | 41.0 | 0.357 | H | -70.4 | -31.4 | 41.0 | 0.357 | 0.0 |
UNL UNL HOH |
8.133 8.280 6.227 |
N CB CB |
O O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLU | A:472 | A:472 | 88.0 | 0.463 | H | -61.6 | -39.7 |