Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 240508 | . | G | A | CCDS3853.1:NM_004168.2:c.1468Gaa>Aaa_NP_004159.2:p.490E>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLU | A:458 | A:490 | 42.0 | NA | H | -61.3 | -36.1 | 42.0 | NA | NA |
HOH |
7.570 |
O |
O |
||
GLU | C:458 | C:490 | 93.0 | 0.489 | H | -66.4 | -33.4 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLU | A:490 | A:448 | 88.0 | 0.463 | H | -51.4 | -40.2 | 88.0 | 0.463 | 0.0 | ||||||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLU | A:490 | A:448 | 101.0 | 0.532 | H | -43.8 | -40.4 | 101.0 | 0.532 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:448 | A:448 | 86.0 | 0.453 | H | -49.1 | -42.0 | 86.0 | 0.453 | 0.0 |
HOH |
3.168 |
N |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:448 | A:448 | 84.0 | 0.442 | H | -52.6 | -38.2 | 84.0 | 0.442 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 106.0 | 0.558 | H | -63.3 | -47.1 | 106.0 | 0.558 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 104.0 | 0.547 | H | -67.8 | -48.2 | 104.0 | 0.547 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 110.0 | 0.579 | H | -66.1 | -47.3 | 110.0 | 0.579 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 104.0 | 0.547 | H | -57.5 | -49.0 | 104.0 | 0.547 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 121.0 | 0.637 | H | -40.3 | -50.9 | 121.0 | 0.637 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 120.0 | 0.632 | H | -65.6 | -53.0 | 120.0 | 0.632 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 111.0 | 0.584 | H | -64.7 | -47.5 | 111.0 | 0.584 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 117.0 | 0.616 | H | -56.7 | -41.1 | 117.0 | 0.616 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 98.0 | 0.516 | H | -68.7 | -42.9 | 98.0 | 0.516 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 92.0 | 0.484 | H | -74.6 | -25.3 | 92.0 | 0.484 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 88.0 | 0.463 | H | -63.4 | -30.5 | 88.0 | 0.463 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 96.0 | 0.505 | H | -65.7 | -39.4 | 96.0 | 0.505 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 82.0 | 0.432 | H | -67.6 | -41.2 | 82.0 | 0.432 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 88.0 | 0.463 | H | -67.3 | -35.4 | 88.0 | 0.463 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 107.0 | 0.563 | H | -39.3 | -42.6 | 107.0 | 0.563 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 119.0 | 0.626 | H | -51.4 | -51.2 | 119.0 | 0.626 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:448 | A:448 | 85.0 | 0.447 | H | -65.5 | -35.9 | 85.0 | 0.447 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:448 | A:448 | 88.0 | 0.463 | H | -55.2 | -30.0 | 88.0 | 0.463 | 0.0 | ||||||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:448 | A:448 | 114.0 | 0.6 | H | -49.6 | -49.7 | 114.0 | 0.6 | 0.0 | ||||||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:447 | A:447 | 95.0 | 0.5 | H | -51.2 | -31.8 | 95.0 | 0.5 | 0.0 |
HOH |
4.715 |
N |
O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:447 | A:447 | 91.0 | 0.479 | H | -47.0 | -26.8 | 91.0 | 0.479 | 0.0 |
HOH |
5.241 |
N |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:447 | A:447 | 110.0 | 0.579 | H | -62.1 | -34.5 | 110.0 | 0.579 | 0.0 |
UNL UNL UNL UNL UNL HOH |
5.057 5.535 9.199 9.799 8.001 2.910 |
O N O O N O |
C2 N3 O O O O |
||
GLU | E:447 | N:447 | 105.0 | 0.553 | H | -63.3 | -33.8 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLU | A:447 | A:447 | 114.0 | 0.6 | H | -60.1 | -33.7 | 114.0 | 0.6 | 0.0 |
HOH |
3.004 |
O |
O |
||
GLU | E:447 | N:447 | 115.0 | 0.605 | H | -60.1 | -35.0 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLU | A:447 | A:447 | 115.0 | 0.605 | H | -54.9 | -31.7 | 115.0 | 0.605 | 0.0 |
HOH |
7.126 |
O |
O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLU | A:447 | A:447 | 98.0 | 0.516 | H | -60.2 | -35.0 | 98.0 | 0.516 | 0.0 |
UNL HOH |
5.322 3.174 |
OE2 O |
C2 O |
||
GLU | E:447 | N:447 | 119.0 | 0.626 | H | -60.4 | -34.3 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 116.0 | 0.611 | H | -71.1 | -15.7 | 116.0 | 0.611 | 0.0 |
UNL HOH |
5.280 4.598 |
O N |
O O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 117.0 | 0.616 | H | -72.4 | -28.3 | 117.0 | 0.616 | 0.0 |
HOH |
4.481 |
N |
O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 106.0 | 0.558 | H | -61.2 | -36.2 | 106.0 | 0.558 | 0.0 |
UNL HOH |
8.303 4.782 |
O N |
O O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLU | A:447 | A:447 | 114.0 | 0.6 | H | -68.4 | -25.9 | 114.0 | 0.6 | 0.0 | ||||||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 115.0 | 0.605 | H | -69.1 | -20.3 | 115.0 | 0.605 | 0.0 |
UNL |
9.596 |
OE1 |
O |
||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 123.0 | 0.647 | H | -67.1 | -22.9 | 123.0 | 0.647 | 0.0 |
HOH |
7.460 |
O |
O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:447 | A:447 | 105.0 | 0.553 | H | -55.5 | -35.2 | 105.0 | 0.553 | 0.0 |
UNL HOH |
8.364 4.787 |
O N |
O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLU | A:490 | A:490 | 71.0 | 0.374 | H | -57.6 | -40.5 |