Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 240511 . G A CCDS3853.1:NM_004168.2:c.1471Gaa>Aaa_NP_004159.2:p.491E>K Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 GLU A:459 A:491 167.0 0.879 H -63.4 -34.4 167.0 0.879 0.0 HOH
 3.159
 OE1
 O
GLU C:459 C:491 125.0 0.658 H -64.5 -34.7 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 GLU A:491 A:449 134.0 0.705 H -60.3 -34.5 134.0 0.705 0.0 HOH
 9.426
 O
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 GLU A:491 A:449 143.0 0.753 H -84.6 -27.4 143.0 0.753 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 GLU A:449 A:449 174.0 0.916 H -60.6 -43.6 174.0 0.916 0.0 HOH
 2.737
 N
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 GLU A:449 A:449 171.0 0.9 H -62.7 -43.7 171.0 0.9 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 159.0 0.837 H -66.1 -20.6 159.0 0.837 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 150.0 0.789 H -82.7 0.8 150.0 0.789 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 168.0 0.884 H -64.1 -21.5 168.0 0.884 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 153.0 0.805 H -55.8 -38.1 153.0 0.805 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 141.0 0.742 H -64.1 -31.5 141.0 0.742 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 138.0 0.726 H -94.6 -0.9 138.0 0.726 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 147.0 0.774 H -80.7 -3.6 147.0 0.774 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 147.0 0.774 H -70.3 -32.0 147.0 0.774 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 141.0 0.742 H -71.9 -24.5 141.0 0.742 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 173.0 0.911 H -71.9 -27.0 173.0 0.911 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 151.0 0.795 H -71.0 -27.9 151.0 0.795 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 143.0 0.753 H -61.6 -35.2 143.0 0.753 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 175.0 0.921 H -70.9 -19.4 175.0 0.921 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 157.0 0.826 H -75.9 -24.5 157.0 0.826 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 135.0 0.711 H -61.8 -40.6 135.0 0.711 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 149.0 0.784 H -71.5 -26.3 149.0 0.784 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 GLU A:449 A:449 161.0 0.847 H -76.2 -19.0 161.0 0.847 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 GLU A:449 A:449 153.0 0.805 H -66.9 -37.0 153.0 0.805 0.0 HOH
 8.861
 CB
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 GLU A:449 A:449 154.0 0.811 H -74.0 -26.0 154.0 0.811 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 GLU A:448 A:448 123.0 0.647 H -71.8 -27.4 123.0 0.647 0.0 HOH
 4.155
 CB
 O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 GLU A:448 A:448 123.0 0.647 H -78.5 -24.4 123.0 0.647 0.0 HOH
 3.715
 CB
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 GLU A:448 A:448 160.0 0.842 H -63.9 -32.0 160.0 0.842 0.0 UNL
UNL
UNL
UNL
UNL
UNL
UNL
HOH
 7.019
5.838
9.256
6.553
6.219
9.774
4.582
3.141
 O
OE2
O
O
O
O
OE1
N
 C2
N3
N1
O
O
O
O
O
GLU E:448 N:448 163.0 0.858 H -64.4 -32.7 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 GLU A:448 A:448 165.0 0.868 H -64.4 -30.1 165.0 0.868 0.0 HOH
 2.953
 N
 O
GLU E:448 N:448 167.0 0.879 H -62.8 -30.1 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 GLU A:448 A:448 157.0 0.826 H -65.4 -35.3 157.0 0.826 0.0 HOH
 4.949
 O
 O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 GLU A:448 A:448 132.0 0.695 H -69.8 -21.1 132.0 0.695 0.0 UNL
HOH
 7.553
2.980
 N
OE2
 C2
O
GLU E:448 N:448 130.0 0.684 H -69.6 -21.6 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 168.0 0.884 H -72.8 -25.9 168.0 0.884 0.0 UNL
HOH
 7.522
4.024
 N
CB
 O
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 159.0 0.837 H -71.8 -24.9 159.0 0.837 0.0 HOH
 4.275
 N
 O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 146.0 0.768 H -68.2 -28.3 146.0 0.768 0.0 HOH
 3.296
 OE2
 O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 GLU A:448 A:448 161.0 0.847 H -66.3 -37.1 161.0 0.847 0.0
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 163.0 0.858 H -66.3 -30.1 163.0 0.858 0.0 HOH
 8.913
 O
 O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 167.0 0.879 H -73.5 -23.8 167.0 0.879 0.0 HOH
 5.040
 O
 O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 GLU A:448 A:448 141.0 0.742 H -69.3 -28.6 141.0 0.742 0.0 HOH
 4.492
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 GLU A:491 A:491 153.0 0.805 H -63.1 -35.9