Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 240536 . T A CCDS3853.1:NM_004168.2:c.1496tTg>tAg_NP_004159.2:p.499L>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 LEU A:467 A:499 12.0 0.071 H -68.2 -32.8 12.0 0.071 0.0 HOH
 5.420
 CD1
 O
LEU C:467 C:499 9.0 0.053 H -70.5 -28.0 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 LEU A:499 A:457 3.0 0.018 H -72.6 -23.1 3.0 0.018 0.0 HOH
 7.966
 CD1
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 LEU A:499 A:457 2.0 0.012 H -66.8 -31.6 2.0 0.012 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 LEU A:457 A:457 9.0 0.053 H -57.6 -29.8 9.0 0.053 0.0 HOH
 3.971
 O
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 LEU A:457 A:457 8.0 0.047 H -54.6 -29.5 8.0 0.047 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 3.0 0.018 H -66.9 -31.5 3.0 0.018 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 9.0 0.053 H -69.7 -26.0 9.0 0.053 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 14.0 0.082 H -75.7 -19.1 14.0 0.082 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 1.0 0.006 H -76.3 -21.9 1.0 0.006 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 12.0 0.071 H -68.8 -27.2 12.0 0.071 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 11.0 0.065 H -70.2 -25.0 11.0 0.065 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 4.0 0.024 H -80.2 -22.7 4.0 0.024 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 4.0 0.024 H -79.4 -18.4 4.0 0.024 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 9.0 0.053 H -81.6 -16.7 9.0 0.053 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 1.0 0.006 H -73.0 -23.6 1.0 0.006 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 12.0 0.071 H -77.8 -25.5 12.0 0.071 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 8.0 0.047 H -81.8 -22.0 8.0 0.047 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 10.0 0.059 H -87.0 -21.8 10.0 0.059 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 10.0 0.059 H -77.3 -32.3 10.0 0.059 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 12.0 0.071 H -76.7 -23.7 12.0 0.071 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 15.0 0.088 H -76.2 -35.7 15.0 0.088 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 LEU A:457 A:457 11.0 0.065 H -76.7 -22.2 11.0 0.065 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 LEU A:457 A:457 10.0 0.059 H -65.8 -32.4 10.0 0.059 0.0 HOH
 5.982
 CD2
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 LEU A:457 A:457 12.0 0.071 H -73.4 -30.3 12.0 0.071 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 LEU A:456 A:456 6.0 0.035 H -75.0 -32.0 6.0 0.035 0.0 HOH
 3.588
 O
 O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 LEU A:456 A:456 8.0 0.047 H -68.8 -37.0 8.0 0.047 0.0 HOH
 5.659
 CD1
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 LEU A:456 A:456 12.0 0.071 H -70.9 -32.3 12.0 0.071 0.0 UNL
UNL
UNL
UNL
UNL
UNL
HOH
 9.433
7.320
6.925
7.463
6.795
9.946
3.586
 N
CD1
CD1
CD2
CD2
N
O
 C2
N1
O
O
O
O
O
LEU E:456 N:456 12.0 0.071 H -72.8 -31.3 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 LEU A:456 A:456 6.0 0.035 H -72.9 -36.7 6.0 0.035 0.0 HOH
 3.667
 O
 O
LEU E:456 N:456 5.0 0.029 H -73.2 -35.8 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 LEU A:456 A:456 5.0 0.029 H -71.3 -31.6 5.0 0.029 0.0 HOH
 3.960
 O
 O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 LEU A:456 A:456 7.0 0.041 H -71.5 -32.4 7.0 0.041 0.0 UNL
HOH
 8.726
3.589
 CD2
O
 C2
O
LEU E:456 N:456 6.0 0.035 H -72.2 -32.6 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 8.0 0.047 H -72.3 -35.8 8.0 0.047 0.0 UNL
UNL
HOH
 7.695
9.952
5.509
 O
N
N
 O2
O
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 7.0 0.041 H -71.6 -30.3 7.0 0.041 0.0 UNL
HOH
 7.479
6.006
 O
CD1
 O2
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 7.0 0.041 H -69.2 -38.8 7.0 0.041 0.0 HOH
 5.508
 CD1
 O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 LEU A:456 A:456 10.0 0.059 H -69.9 -35.0 10.0 0.059 0.0 HOH
 8.941
 O
 O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 8.0 0.047 H -70.8 -30.1 8.0 0.047 0.0 HOH
 7.603
 CD1
 O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 6.0 0.035 H -69.0 -28.2 6.0 0.035 0.0 HOH
 5.885
 CD1
 O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 LEU A:456 A:456 6.0 0.035 H -65.6 -42.3 6.0 0.035 0.0 HOH
 6.089
 CD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 LEU A:499 A:499 4.0 0.024 H -73.1 -38.0