Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 240563 | . | C | A | CCDS3853.1:NM_004168.2:c.1523aCa>aAa_NP_004159.2:p.508T>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | THR | A:476 | A:508 | 7.0 | 0.05 | H | -65.3 | -42.7 | 7.0 | 0.05 | 0.0 |
HOH |
4.862 |
CG2 |
O |
||
| THR | C:476 | C:508 | 3.0 | 0.021 | H | -67.7 | -42.9 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | THR | A:508 | A:466 | 3.0 | 0.021 | H | -46.6 | -52.0 | 3.0 | 0.021 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | THR | A:508 | A:466 | 3.0 | 0.021 | H | -46.5 | -46.6 | 3.0 | 0.021 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -42.8 | -46.3 | 5.0 | 0.036 | 0.0 |
HOH |
3.188 |
CG2 |
O |
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| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -45.5 | -47.3 | 5.0 | 0.036 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -52.1 | -48.3 | 4.0 | 0.029 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -56.3 | -36.5 | 5.0 | 0.036 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -48.0 | -45.6 | 4.0 | 0.029 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 2.0 | 0.014 | H | -52.2 | -47.0 | 2.0 | 0.014 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -49.0 | -43.1 | 5.0 | 0.036 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -58.4 | -45.6 | 4.0 | 0.029 | 0.007 |
B:Q007T0:0.007 |
|||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -57.7 | -48.2 | 4.0 | 0.029 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -54.0 | -48.3 | 4.0 | 0.029 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -55.7 | -50.6 | 4.0 | 0.029 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 3.0 | 0.021 | H | -60.9 | -47.8 | 3.0 | 0.021 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 2.0 | 0.014 | H | -53.1 | -47.9 | 2.0 | 0.014 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -52.4 | -49.3 | 4.0 | 0.029 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 3.0 | 0.021 | H | -53.0 | -43.7 | 3.0 | 0.021 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -42.4 | -50.0 | 5.0 | 0.036 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 5.0 | 0.036 | H | -51.5 | -45.4 | 5.0 | 0.036 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -48.1 | -52.3 | 4.0 | 0.029 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -60.2 | -43.8 | 4.0 | 0.029 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:466 | A:466 | 7.0 | 0.05 | H | -45.6 | -48.6 | 7.0 | 0.05 | 0.0 | ||||||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:466 | A:466 | 4.0 | 0.029 | H | -39.1 | -50.4 | 4.0 | 0.029 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:465 | A:465 | 4.0 | 0.029 | H | -38.6 | -55.9 | 4.0 | 0.029 | 0.0 |
HOH |
3.328 |
CB |
O |
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| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -34.2 | -61.6 | 6.0 | 0.043 | 0.0 |
HOH |
3.020 |
CB |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -52.4 | -49.0 | 6.0 | 0.043 | 0.0 |
UNL UNL UNL UNL UNL HOH |
7.397 6.890 7.547 8.927 8.127 3.324 |
CG2 CG2 O O O CB |
N3 O O O O O |
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| THR | E:465 | N:465 | 6.0 | 0.043 | H | -53.5 | -46.8 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -47.3 | -46.8 | 6.0 | 0.043 | 0.0 |
HOH |
3.420 |
OG1 |
O |
||
| THR | E:465 | N:465 | 6.0 | 0.043 | H | -48.2 | -48.3 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:465 | A:465 | 5.0 | 0.036 | H | -36.9 | -56.8 | 5.0 | 0.036 | 0.0 |
HOH |
3.117 |
OG1 |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -45.7 | -50.6 | 6.0 | 0.043 | 0.0 |
UNL HOH |
7.124 3.327 |
C CB |
C2 O |
||
| THR | E:465 | N:465 | 6.0 | 0.043 | H | -46.4 | -50.0 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -51.5 | -48.0 | 6.0 | 0.043 | 0.0 |
PEG UNL HOH |
6.990 3.368 3.497 |
CG2 N CG2 |
O4 C O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 5.0 | 0.036 | H | -58.9 | -43.0 | 5.0 | 0.036 | 0.0 |
PEG UNL HOH |
7.396 3.354 3.423 |
CG2 N CB |
O4 C O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -57.5 | -43.4 | 6.0 | 0.043 | 0.0 |
PEG HOH |
7.143 3.271 |
CG2 OG1 |
O4 O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | THR | A:465 | A:465 | 5.0 | 0.036 | H | -57.7 | -38.7 | 5.0 | 0.036 | 0.0 |
PEG HOH |
7.866 3.139 |
CG2 CB |
C4 O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -65.4 | -42.2 | 6.0 | 0.043 | 0.0 |
HOH |
4.014 |
CG2 |
O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 4.0 | 0.029 | H | -62.2 | -37.9 | 4.0 | 0.029 | 0.0 |
PEG UNL HOH |
7.452 5.039 3.374 |
CG2 CB N |
O4 O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:465 | A:465 | 6.0 | 0.043 | H | -65.2 | -49.3 | 6.0 | 0.043 | 0.0 |
PEG HOH |
6.868 3.273 |
CG2 N |
O4 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | THR | A:508 | A:508 | 5.0 | 0.036 | H | -50.1 | -45.7 | |