Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 240574 . C A CCDS3853.1:NM_004168.2:c.1534Cga>Aga_NP_004159.2:p.512R>R Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 ARG A:480 A:512 56.0 0.249 H -63.8 -39.2 23.0 0.102 0.147 B:Q9NX18:0.147
 HOH
 2.674
 NH1
 O
ARG C:480 C:512 56.0 0.249 H -66.2 -38.4 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 ARG A:512 A:470 58.0 0.258 H -47.3 -55.1 35.0 0.156 0.102 B:Q007T0:0.102
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 ARG A:512 A:470 59.0 0.262 H -58.0 -41.5 38.0 0.169 0.093 B:Q007T0:0.093
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 ARG A:470 A:470 59.0 0.262 H -54.1 -40.3 40.0 0.178 0.084 B:Q007T0:0.084
 HOH
 2.426
 NH2
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 ARG A:470 A:470 58.0 0.258 H -57.0 -40.9 40.0 0.178 0.08 B:None:0.08
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 51.0 0.227 H -54.9 -45.2 31.0 0.138 0.089 B:Q007T0:0.089
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 58.0 0.258 H -67.5 -41.4 35.0 0.156 0.102 B:Q007T0:0.102
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 52.0 0.231 H -57.3 -44.1 31.0 0.138 0.093 B:Q007T0:0.093
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 51.0 0.227 H -62.3 -46.1 31.0 0.138 0.089 B:Q007T0:0.089
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 48.0 0.213 H -69.4 -48.9 32.0 0.142 0.071 B:Q007T0:0.071
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 63.0 0.28 H -65.5 -49.9 35.0 0.156 0.124 B:Q007T0:0.124
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 54.0 0.24 H -63.7 -40.3 31.0 0.138 0.102 B:Q007T0:0.102
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 50.0 0.222 H -68.1 -37.3 30.0 0.133 0.089 B:Q007T0:0.089
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 59.0 0.262 H -66.0 -43.8 33.0 0.147 0.115 B:Q007T0:0.116
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 48.0 0.213 H -70.2 -43.6 33.0 0.147 0.066 B:Q007T0:0.067
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 52.0 0.231 H -62.5 -46.6 33.0 0.147 0.084 B:Q007T0:0.084
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 56.0 0.249 H -62.4 -46.3 33.0 0.147 0.102 B:Q007T0:0.102
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 52.0 0.231 H -69.6 -43.8 32.0 0.142 0.089 B:Q007T0:0.089
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 51.0 0.227 H -61.4 -43.3 33.0 0.147 0.08 B:Q007T0:0.08
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 57.0 0.253 H -53.7 -45.1 32.0 0.142 0.111 B:Q007T0:0.111
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 56.0 0.249 H -63.6 -55.4 33.0 0.147 0.102 B:Q007T0:0.102
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ARG A:470 A:470 67.0 0.298 H -61.6 -41.6 39.0 0.173 0.125 B:Q007T0:0.124
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ARG A:470 A:470 52.0 0.231 H -55.2 -39.8 37.0 0.164 0.067 B:Q007T0:0.067
 HOH
 9.690
 O
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ARG A:470 A:470 61.0 0.271 H -57.1 -42.0 39.0 0.173 0.098 B:Q007T0:0.098
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 ARG A:469 A:469 55.0 0.244 H -56.2 -49.8 35.0 0.156 0.088 B:Q9YHT2:0.089
 UNL
HOH
 9.440
2.764
 O
CD
 O1
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 ARG A:469 A:469 55.0 0.244 H -44.0 -56.7 33.0 0.147 0.097 B:3851612:0.098
 HOH
 3.154
 NE
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 ARG A:469 A:469 60.0 0.267 H -63.7 -43.7 34.0 0.151 0.116 B:Q9YHT2:0.116
 UNL
UNL
UNL
UNL
UNL
UNL
UNL
UNL
UNL
UNL
HOH
 3.701
8.498
4.056
6.289
9.821
9.301
8.174
3.381
8.318
7.020
2.916
 NH1
NH1
NH1
C
N
O
N
NH2
NE
NH2
NH1
 N3
O2
O
O
O
O
O
O
N1
O
O
ARG E:469 N:469 58.0 0.258 H -67.0 -42.6 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ARG A:469 A:469 61.0 0.271 H -65.5 -47.5 36.0 0.16 0.111 B:Q9YHT2:0.111
 AZI
HOH
 9.236
2.865
 NE
NH1
 N1
O
ARG E:469 N:469 61.0 0.271 H -65.5 -46.5 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ARG A:469 A:469 57.0 0.253 H -45.3 -49.1 34.0 0.151 0.102 B:Q9YHT2:0.102
 UNL
HOH
 9.070
2.636
 O
NH1
 O1
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 ARG A:469 A:469 54.0 0.24 H -66.4 -45.4 34.0 0.151 0.089 B:Q9YHT2:0.089
 UNL
HOH
 7.327
2.644
 NH1
NH2
 C2
O
ARG E:469 N:469 52.0 0.231 H -66.6 -45.1 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 62.0 0.276 H -54.4 -45.0 37.0 0.164 0.112 B:Q9YHT2:0.111
 PEG
UNL
UNL
UNL
HOH
 3.240
8.894
8.678
5.713
2.648
 NE
NH1
NE
NH2
NH1
 C3
C7
O3
O1
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 62.0 0.276 H -68.3 -39.9 36.0 0.16 0.116 B:Q9YHT2:0.116
 PEG
UNL
UNL
UNL
HOH
 3.508
8.354
8.098
6.378
2.750
 CZ
NH1
NE
NH2
NH2
 C4
O8
O05
O1
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 62.0 0.276 H -62.6 -44.3 37.0 0.164 0.112 B:Q9YHT2:0.111
 PEG
UNL
UNL
UNL
HOH
 3.198
8.734
8.732
8.022
2.659
 NE
NH1
NE
NH2
NH1
 C3
C7
O3
O2
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 ARG A:469 A:469 65.0 0.289 H -59.9 -34.0 39.0 0.173 0.116 B:Q9YHT2:0.116
 PEG
UNL
UNL
HOH
 3.219
8.517
8.671
2.701
 CD
NH1
NE
NH1
 O2
C7
O3
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 64.0 0.284 H -64.3 -34.1 38.0 0.169 0.115 B:Q9YHT2:0.116
 UNL
UNL
HOH
 9.111
8.549
2.908
 NH1
NE
NH1
 C7
N3
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 61.0 0.271 H -64.9 -33.3 35.0 0.156 0.115 B:Q9YHT2:0.116
 PEG
UNL
UNL
UNL
UNL
HOH
 3.543
9.714
8.911
9.101
4.919
3.797
 NE
NH1
NE
NH2
NH2
NE
 C3
C5
O3
O2
O
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ARG A:469 A:469 65.0 0.289 H -59.8 -42.8 39.0 0.173 0.116 B:Q9YHT2:0.116
 PEG
UNL
UNL
UNL
HOH
 3.110
8.848
8.754
8.331
2.922
 NE
NH1
NE
NH2
NH1
 C3
C7
O3
O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 ARG A:512 A:512 41.0 0.182 H -57.6 -49.1