Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251126 | . | C | A | CCDS3853.1:NM_004168.2:c.1571gCc>gAc_NP_004159.2:p.524A>D | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ALA | A:492 | A:524 | 12.0 | 0.104 | S | -102.0 | -132.1 | 12.0 | 0.104 | 0.0 |
GOL HOH |
5.437 6.151 |
O O |
O2 O |
||
| ALA | C:492 | C:524 | 7.0 | 0.061 | S | -101.4 | -127.5 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ALA | A:524 | A:482 | 25.0 | 0.217 | S | -71.1 | -162.7 | 25.0 | 0.217 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:524 | A:482 | 26.0 | 0.226 | S | -79.2 | -155.9 | 26.0 | 0.226 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:482 | A:482 | 23.0 | 0.2 | S | -87.2 | -151.2 | 23.0 | 0.2 | 0.0 |
HOH |
2.813 |
O |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:482 | A:482 | 23.0 | 0.2 | S | -90.6 | -152.0 | 23.0 | 0.2 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 25.0 | 0.217 | S | -100.1 | -151.2 | 25.0 | 0.217 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 24.0 | 0.209 | S | -94.9 | -154.3 | 24.0 | 0.209 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 25.0 | 0.217 | S | -86.3 | -160.6 | 25.0 | 0.217 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 28.0 | 0.243 | S | -83.4 | -158.1 | 28.0 | 0.243 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 29.0 | 0.252 | S | -78.1 | -157.9 | 29.0 | 0.252 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 19.0 | 0.165 | S | -117.1 | -149.9 | 19.0 | 0.165 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 27.0 | 0.235 | S | -78.7 | -160.1 | 27.0 | 0.235 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 27.0 | 0.235 | S | -85.2 | -155.5 | 27.0 | 0.235 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 25.0 | 0.217 | S | -78.1 | -155.8 | 25.0 | 0.217 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 22.0 | 0.191 | S | -79.1 | -155.7 | 22.0 | 0.191 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 23.0 | 0.2 | S | -77.9 | -154.4 | 23.0 | 0.2 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 26.0 | 0.226 | S | -87.7 | -150.5 | 26.0 | 0.226 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 26.0 | 0.226 | S | -81.8 | -160.7 | 26.0 | 0.226 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 24.0 | 0.209 | S | -73.8 | -164.5 | 24.0 | 0.209 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 17.0 | 0.148 | S | -77.7 | -153.4 | 17.0 | 0.148 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 27.0 | 0.235 | S | -86.3 | -164.9 | 27.0 | 0.235 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:482 | A:482 | 22.0 | 0.191 | S | -78.6 | -149.2 | 22.0 | 0.191 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:482 | A:482 | 30.0 | 0.261 | S | -88.7 | -159.8 | 30.0 | 0.261 | 0.0 |
HOH |
2.763 |
O |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:482 | A:482 | 27.0 | 0.235 | S | -89.6 | -157.3 | 27.0 | 0.235 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:481 | A:481 | 27.0 | 0.235 | S | -94.0 | -163.3 | 27.0 | 0.235 | 0.0 |
HOH |
2.736 |
N |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:481 | A:481 | 29.0 | 0.252 | S | -95.8 | -151.1 | 29.0 | 0.252 | 0.0 |
HOH |
2.487 |
N |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:481 | A:481 | 29.0 | 0.252 | S | -96.6 | -156.0 | 29.0 | 0.252 | 0.0 |
UNL UNL UNL HOH |
6.397 7.402 8.651 2.993 |
CB CB CB N |
O O O O |
||
| ALA | E:481 | N:481 | 29.0 | 0.252 | S | -96.3 | -158.7 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:481 | A:481 | 29.0 | 0.252 | S | -92.9 | -157.2 | 29.0 | 0.252 | 0.0 |
HOH |
2.914 |
N |
O |
||
| ALA | E:481 | N:481 | 30.0 | 0.261 | S | -93.7 | -158.2 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:481 | A:481 | 28.0 | 0.243 | S | -98.6 | -158.8 | 28.0 | 0.243 | 0.0 |
HOH |
2.612 |
N |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ALA | A:481 | A:481 | 30.0 | 0.261 | S | -92.6 | -157.0 | 30.0 | 0.261 | 0.0 |
HOH |
3.029 |
N |
O |
||
| ALA | E:481 | N:481 | 30.0 | 0.261 | S | -92.8 | -157.3 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 25.0 | 0.217 | S | -93.5 | -158.1 | 25.0 | 0.217 | 0.0 |
HOH |
2.638 |
N |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 29.0 | 0.252 | S | -93.3 | -157.3 | 29.0 | 0.252 | 0.0 |
HOH |
3.378 |
O |
O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 28.0 | 0.243 | S | -93.2 | -157.8 | 28.0 | 0.243 | 0.0 |
HOH |
3.197 |
O |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ALA | A:481 | A:481 | 29.0 | 0.252 | S | -88.1 | -158.1 | 29.0 | 0.252 | 0.0 | ||||||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 28.0 | 0.243 | S | -79.7 | -152.8 | 28.0 | 0.243 | 0.0 |
HOH |
3.289 |
O |
O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 28.0 | 0.243 | S | -84.7 | -149.2 | 28.0 | 0.243 | 0.0 |
HOH |
3.074 |
O |
O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:481 | A:481 | 28.0 | 0.243 | S | -95.8 | -157.3 | 28.0 | 0.243 | 0.0 |
HOH |
3.231 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ALA | A:524 | A:524 | 28.0 | 0.243 | S | -74.0 | -159.8 | |