Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251163 | . | T | A | CCDS3853.1:NM_004168.2:c.1608tgT>tgA_NP_004159.2:p.536C>* | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | CYS | A:504 | A:536 | 7.0 | 0.052 | H | -61.5 | -39.9 | 7.0 | 0.052 | 0.0 |
EDO HOH |
4.323 8.332 |
CB SG |
O2 O |
||
| CYS | C:504 | C:536 | 8.0 | 0.059 | H | -60.4 | -38.9 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | CYS | A:536 | A:494 | 3.0 | 0.022 | H | -57.6 | -71.1 | 3.0 | 0.022 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | CYS | A:536 | A:494 | 8.0 | 0.059 | H | -56.9 | -52.3 | 8.0 | 0.059 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | CYS | A:494 | A:494 | 6.0 | 0.044 | H | -57.7 | -56.2 | 6.0 | 0.044 | 0.0 |
HOH |
4.737 |
SG |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | CYS | A:494 | A:494 | 6.0 | 0.044 | H | -55.9 | -60.9 | 6.0 | 0.044 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 8.0 | 0.059 | H | -60.2 | -55.3 | 8.0 | 0.059 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 0.0 | 0.0 | H | -72.0 | -56.7 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 7.0 | 0.052 | H | -63.5 | -53.9 | 7.0 | 0.052 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 2.0 | 0.015 | H | -57.0 | -45.8 | 2.0 | 0.015 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 5.0 | 0.037 | H | -54.2 | -54.0 | 5.0 | 0.037 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 3.0 | 0.022 | H | -60.8 | -55.4 | 3.0 | 0.022 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 4.0 | 0.03 | H | -62.5 | -52.7 | 4.0 | 0.03 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 6.0 | 0.044 | H | -71.4 | -49.3 | 6.0 | 0.044 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 5.0 | 0.037 | H | -59.6 | -51.1 | 5.0 | 0.037 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 7.0 | 0.052 | H | -59.8 | -47.8 | 7.0 | 0.052 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 1.0 | 0.007 | H | -64.6 | -52.9 | 1.0 | 0.007 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 0.0 | 0.0 | H | -58.5 | -52.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 6.0 | 0.044 | H | -63.7 | -60.2 | 6.0 | 0.044 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 1.0 | 0.007 | H | -62.0 | -43.5 | 1.0 | 0.007 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 3.0 | 0.022 | H | -63.6 | -54.1 | 3.0 | 0.022 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 5.0 | 0.037 | H | -61.9 | -62.6 | 5.0 | 0.037 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | CYS | A:494 | A:494 | 4.0 | 0.03 | H | -67.3 | -43.7 | 4.0 | 0.03 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | CYS | A:494 | A:494 | 8.0 | 0.059 | H | -59.7 | -61.0 | 8.0 | 0.059 | 0.0 |
HOH |
6.716 |
O |
O |
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| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | CYS | A:494 | A:494 | 4.0 | 0.03 | H | -59.5 | -56.1 | 4.0 | 0.03 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | CYS | A:493 | A:493 | 4.0 | 0.03 | H | -64.4 | -41.3 | 4.0 | 0.03 | 0.0 |
UNL UNL HOH |
5.235 8.910 5.108 |
SG O SG |
O1 O1 O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | CYS | A:493 | A:493 | 5.0 | 0.037 | H | -57.5 | -37.0 | 5.0 | 0.037 | 0.0 |
HOH |
4.229 |
CB |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | CYS | A:493 | A:493 | 6.0 | 0.044 | H | -57.8 | -47.2 | 6.0 | 0.044 | 0.0 |
UNL UNL UNL UNL HOH |
4.256 8.172 9.349 6.912 4.990 |
SG O N O O |
O1 O O O O |
||
| CYS | E:493 | N:493 | 7.0 | 0.052 | H | -56.7 | -47.5 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | CYS | A:493 | A:493 | 3.0 | 0.022 | H | -59.1 | -46.7 | 3.0 | 0.022 | 0.0 |
HOH |
4.068 |
CB |
O |
||
| CYS | E:493 | N:493 | 4.0 | 0.03 | H | -60.4 | -46.7 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | CYS | A:493 | A:493 | 3.0 | 0.022 | H | -69.9 | -49.3 | 3.0 | 0.022 | 0.0 |
UNL UNL HOH |
5.373 8.613 5.397 |
SG O O |
O1 O1 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | CYS | A:493 | A:493 | 3.0 | 0.022 | H | -60.6 | -43.7 | 3.0 | 0.022 | 0.0 |
UNL HOH |
7.392 3.852 |
O CB |
C2 O |
||
| CYS | E:493 | N:493 | 3.0 | 0.022 | H | -61.2 | -43.8 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 6.0 | 0.044 | H | -63.8 | -43.3 | 6.0 | 0.044 | 0.0 |
HOH |
5.107 |
SG |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 8.0 | 0.059 | H | -67.6 | -45.2 | 8.0 | 0.059 | 0.0 |
UNL UNL HOH |
4.895 9.884 5.360 |
O SG O |
O1 O O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 6.0 | 0.044 | H | -62.4 | -45.2 | 6.0 | 0.044 | 0.0 |
MOH HOH |
5.999 5.405 |
O SG |
C O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | CYS | A:493 | A:493 | 6.0 | 0.044 | H | -72.1 | -42.8 | 6.0 | 0.044 | 0.0 |
HOH |
9.840 |
SG |
O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 7.0 | 0.052 | H | -63.0 | -42.0 | 7.0 | 0.052 | 0.0 | ||||||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 6.0 | 0.044 | H | -64.5 | -43.6 | 6.0 | 0.044 | 0.0 |
UNL HOH |
6.138 5.595 |
O SG |
O2 O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | CYS | A:493 | A:493 | 7.0 | 0.052 | H | -63.2 | -48.8 | 7.0 | 0.052 | 0.0 |
UNL HOH |
6.480 5.446 |
O SG |
O3 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | CYS | A:536 | A:536 | 7.0 | 0.052 | H | -55.7 | -47.8 | |