Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 251184 . T A CCDS3853.1:NM_004168.2:c.1629taT>taA_NP_004159.2:p.543Y>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 TYR A:511 A:543 19.0 0.083 H -70.2 -36.4 19.0 0.083 0.0 HOH
 5.566
 OH
 O
TYR C:511 C:543 30.0 0.13 H -66.6 -38.1 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 TYR A:543 A:501 22.0 0.096 H -68.1 -30.7 22.0 0.096 0.0 HOH
 3.438
 OH
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 TYR A:543 A:501 30.0 0.13 H -62.9 -37.7 30.0 0.13 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 TYR A:501 A:501 28.0 0.122 H -54.9 -34.5 28.0 0.122 0.0 HOH
 4.303
 OH
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 TYR A:501 A:501 27.0 0.117 H -58.5 -33.6 27.0 0.117 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 29.0 0.126 H -74.8 -34.9 29.0 0.126 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 26.0 0.113 H -76.6 -33.8 26.0 0.113 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 26.0 0.113 H -76.4 -38.7 26.0 0.113 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 20.0 0.087 H -71.7 -30.2 20.0 0.087 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 33.0 0.143 H -72.2 -27.0 33.0 0.143 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 32.0 0.139 H -67.6 -29.3 32.0 0.139 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 23.0 0.1 H -87.8 -31.2 23.0 0.1 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 28.0 0.122 H -75.0 -31.4 28.0 0.122 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 31.0 0.135 H -73.7 -32.3 31.0 0.135 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 29.0 0.126 H -68.1 -33.9 29.0 0.126 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 28.0 0.122 H -74.3 -33.3 28.0 0.122 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 28.0 0.122 H -71.6 -31.6 28.0 0.122 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 21.0 0.091 H -74.8 -32.2 21.0 0.091 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 24.0 0.104 H -72.8 -35.0 24.0 0.104 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 31.0 0.135 H -76.3 -35.9 31.0 0.135 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 27.0 0.117 H -72.0 -37.2 27.0 0.117 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:501 A:501 23.0 0.1 H -74.5 -22.9 23.0 0.1 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:501 A:501 26.0 0.113 H -59.3 -34.3 26.0 0.113 0.0 HOH
 7.824
 CB
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:501 A:501 26.0 0.113 H -65.6 -36.6 26.0 0.113 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 TYR A:500 A:500 25.0 0.109 H -60.7 -43.1 25.0 0.109 0.0 UNL
HOH
 8.577
3.795
 N
CD2
 O1
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 TYR A:500 A:500 28.0 0.122 H -63.7 -40.4 28.0 0.122 0.0 HOH
 6.173
 OH
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 TYR A:500 A:500 29.0 0.126 H -62.7 -43.4 29.0 0.126 0.0 UNL
UNL
UNL
UNL
HOH
 5.935
7.018
3.855
9.081
2.870
 OH
N
OH
N
OH
 O
O
O
O
O
TYR E:500 N:500 30.0 0.13 H -60.7 -44.3 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:500 A:500 27.0 0.117 H -63.5 -48.0 27.0 0.117 0.0 UNL
UNL
HOH
 9.627
8.834
2.844
 C
N
O
 O1
O1
O
TYR E:500 N:500 28.0 0.122 H -64.1 -47.6 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:500 A:500 37.0 0.161 H -57.9 -35.2 37.0 0.161 0.0 UNL
HOH
 8.487
3.227
 N
OH
 O1
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 TYR A:500 A:500 29.0 0.126 H -62.4 -47.8 29.0 0.126 0.0 UNL
UNL
UNL
HOH
 8.628
3.674
8.720
2.955
 O
O
N
OH
 C2
C2
C2
O
TYR E:500 N:500 30.0 0.13 H -61.6 -47.4 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 30.0 0.13 H -68.5 -40.3 30.0 0.13 0.0 MN
HOH
 9.127
6.197
 C
N
 MN
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 34.0 0.148 H -63.9 -38.1 34.0 0.148 0.0 MG
UNL
HOH
 8.800
8.727
5.501
 C
CB
N
 MG
O2
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 28.0 0.122 H -63.2 -47.2 28.0 0.122 0.0 UNL
MOH
HOH
 8.565
7.661
4.199
 O
CB
OH
 N3
O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 TYR A:500 A:500 27.0 0.117 H -64.0 -40.3 27.0 0.117 0.0
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 29.0 0.126 H -66.4 -42.0 29.0 0.126 0.0 HOH
 4.581
 OH
 O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 32.0 0.139 H -62.8 -39.5 32.0 0.139 0.0 UNL
UNL
HOH
 8.426
7.374
4.040
 O
CD2
O
 N1
O1
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:500 A:500 31.0 0.135 H -64.7 -42.8 31.0 0.135 0.0 UNL
UNL
HOH
 8.665
6.061
4.521
 O
CD2
OH
 N2
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 TYR A:543 A:543 28.0 0.122 H -64.4 -45.9