Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251525 | . | T | A | CCDS3853.1:NM_004168.2:c.1736aTc>aAc_NP_004159.2:p.579I>N | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ILE | A:547 | A:579 | 0.0 | 0.0 | H | -77.2 | -31.2 | 0.0 | 0.0 | 0.0 |
EDO HOH |
7.245 5.686 |
O N |
O2 O |
||
| ILE | C:547 | C:579 | 0.0 | 0.0 | H | -76.5 | -28.2 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ILE | A:579 | A:537 | 1.0 | 0.006 | H | -74.5 | -39.7 | 1.0 | 0.006 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ILE | A:579 | A:537 | 2.0 | 0.011 | H | -77.5 | -46.3 | 2.0 | 0.011 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ILE | A:537 | A:537 | 2.0 | 0.011 | H | -66.7 | -41.8 | 2.0 | 0.011 | 0.0 |
HOH |
6.116 |
CD1 |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -63.5 | -42.9 | 1.0 | 0.006 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -74.0 | -42.1 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -76.5 | -39.9 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -68.6 | -40.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -76.0 | -40.6 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -83.7 | -31.3 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -70.3 | -44.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -70.2 | -38.2 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -73.2 | -39.5 | 1.0 | 0.006 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -76.2 | -38.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -79.1 | -35.6 | 1.0 | 0.006 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -75.4 | -39.1 | 1.0 | 0.006 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -70.1 | -40.2 | 1.0 | 0.006 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -85.4 | -35.2 | 0.0 | 0.0 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -74.9 | -37.6 | 0.0 | 0.0 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -70.8 | -36.0 | 0.0 | 0.0 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -84.7 | -40.8 | 1.0 | 0.006 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -84.7 | -44.5 | 1.0 | 0.006 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ILE | A:537 | A:537 | 1.0 | 0.006 | H | -71.5 | -41.5 | 1.0 | 0.006 | 0.0 |
HOH |
7.995 |
CG2 |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ILE | A:537 | A:537 | 0.0 | 0.0 | H | -71.6 | -44.7 | 0.0 | 0.0 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -73.7 | -30.8 | 0.0 | 0.0 | 0.0 |
UNL HOH |
7.705 5.444 |
O O |
O1 O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -81.6 | -26.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.210 |
N |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -78.5 | -32.2 | 0.0 | 0.0 | 0.0 |
UNL UNL HOH |
6.875 9.082 5.218 |
O CD1 O |
O1 O O |
||
| ILE | E:536 | N:536 | 0.0 | 0.0 | H | -80.6 | -31.8 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -74.9 | -33.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.198 |
O |
O |
||
| ILE | E:536 | N:536 | 0.0 | 0.0 | H | -73.6 | -33.9 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -71.8 | -34.0 | 0.0 | 0.0 | 0.0 |
UNL HOH |
7.920 6.123 |
O O |
O1 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -72.5 | -37.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.210 |
O |
O |
||
| ILE | E:536 | N:536 | 0.0 | 0.0 | H | -74.8 | -35.6 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -79.4 | -30.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.455 |
O |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -80.1 | -28.2 | 0.0 | 0.0 | 0.0 |
UNL HOH |
5.947 5.554 |
N O |
O O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -83.4 | -34.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.637 |
N |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -78.3 | -29.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.823 |
N |
O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -75.0 | -23.7 | 0.0 | 0.0 | 0.0 | ||||||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -84.8 | -26.7 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.565 5.264 |
CG2 O |
O2 O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ILE | A:536 | A:536 | 0.0 | 0.0 | H | -81.7 | -33.9 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.222 5.715 |
CG2 O |
O3 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ILE | A:579 | A:579 | 0.0 | 0.0 | H | -76.6 | -36.7 | |