Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 251529 . C A CCDS3853.1:NM_004168.2:c.1740taC>taA_NP_004159.2:p.580Y>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 TYR A:548 A:580 64.0 0.278 H -72.6 -36.9 64.0 0.278 0.0 EDO
HOH
 4.753
5.000
 CE1
O
 O2
O
TYR C:548 C:580 61.0 0.265 H -75.1 -38.8 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 TYR A:580 A:538 49.0 0.213 H -64.5 -54.6 49.0 0.213 0.0
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 TYR A:580 A:538 54.0 0.235 H -61.6 -36.6 54.0 0.235 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 TYR A:538 A:538 52.0 0.226 H -66.3 -52.8 52.0 0.226 0.0 HOH
 2.932
 OH
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 TYR A:538 A:538 53.0 0.23 H -67.9 -51.0 53.0 0.23 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 52.0 0.226 H -67.2 -48.0 52.0 0.226 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 48.0 0.209 H -72.0 -41.9 48.0 0.209 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 52.0 0.226 H -69.4 -48.6 52.0 0.226 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 50.0 0.217 H -69.3 -40.6 50.0 0.217 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 50.0 0.217 H -73.0 -45.3 50.0 0.217 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 42.0 0.183 H -68.2 -35.3 42.0 0.183 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 41.0 0.178 H -70.8 -39.1 41.0 0.178 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 43.0 0.187 H -70.9 -34.8 43.0 0.187 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 51.0 0.222 H -73.1 -35.6 51.0 0.222 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 44.0 0.191 H -74.4 -37.9 44.0 0.191 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 50.0 0.217 H -70.7 -40.9 50.0 0.217 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 40.0 0.174 H -70.1 -43.1 40.0 0.174 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 47.0 0.204 H -74.9 -35.4 47.0 0.204 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 48.0 0.209 H -70.5 -37.7 48.0 0.209 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 48.0 0.209 H -72.8 -43.1 48.0 0.209 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 49.0 0.213 H -66.7 -46.2 49.0 0.213 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:538 A:538 44.0 0.191 H -70.3 -32.2 44.0 0.191 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:538 A:538 54.0 0.235 H -65.3 -37.9 54.0 0.235 0.0 HOH
 3.005
 OH
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:538 A:538 47.0 0.204 H -66.8 -39.2 47.0 0.204 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 TYR A:537 A:537 44.0 0.191 H -73.8 -35.1 44.0 0.191 0.0 UNL
HOH
 4.305
2.927
 CE2
CE2
 O1
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 TYR A:537 A:537 44.0 0.191 H -76.4 -40.5 44.0 0.191 0.0 HOH
 3.108
 CE2
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 TYR A:537 A:537 62.0 0.27 H -70.3 -39.3 62.0 0.27 0.0 UNL
UNL
HOH
 4.390
9.605
2.594
 CE1
OH
O
 O1
O
O
TYR E:537 N:537 61.0 0.265 H -69.7 -40.9 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:537 A:537 49.0 0.213 H -69.8 -39.8 49.0 0.213 0.0 HOH
 2.691
 O
 O
TYR E:537 N:537 49.0 0.213 H -70.2 -39.7 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:537 A:537 52.0 0.226 H -72.6 -33.5 52.0 0.226 0.0 UNL
HOH
 5.124
3.441
 CE2
CE2
 O1
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 TYR A:537 A:537 49.0 0.213 H -68.2 -42.9 49.0 0.213 0.0 UNL
UNL
HOH
 6.939
9.984
2.694
 CE2
OH
O
 C2
C2
O
TYR E:537 N:537 47.0 0.204 H -69.0 -43.0 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 61.0 0.265 H -73.4 -40.6 61.0 0.265 0.0 HOH
 2.776
 O
 O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 59.0 0.257 H -72.2 -41.0 59.0 0.257 0.0 UNL
UNL
HOH
 4.786
5.371
2.874
 OH
C
O
 C
O
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 60.0 0.261 H -67.5 -34.4 60.0 0.261 0.0 MOH
HOH
 3.801
2.897
 OH
O
 O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 TYR A:537 A:537 60.0 0.261 H -76.3 -39.8 60.0 0.261 0.0 HOH
 5.045
 C
 O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 59.0 0.257 H -81.7 -34.1 59.0 0.257 0.0
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 60.0 0.261 H -75.0 -37.2 60.0 0.261 0.0 UNL
HOH
 3.300
2.511
 OH
O
 O2
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:537 A:537 63.0 0.274 H -70.0 -36.5 63.0 0.274 0.0 UNL
HOH
 4.166
3.020
 OH
O
 O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 TYR A:580 A:580 68.0 0.296 H -68.3 -39.7