Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251543 | . | G | A | CCDS3853.1:NM_004168.2:c.1754cGg>cAg_NP_004159.2:p.585R>Q | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ARG | A:553 | A:585 | 0.0 | 0.0 | -71.8 | 96.7 | 0.0 | 0.0 | 0.0 |
MLI EDO EDO HOH |
9.678 9.797 9.079 3.706 |
NH2 CD N N |
O8 O2 O1 O |
|||
| ARG | C:553 | C:585 | 0.0 | 0.0 | -68.1 | 95.8 | NA | NA | NA | ||||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ARG | A:585 | A:543 | 0.0 | 0.0 | -74.6 | 119.6 | 0.0 | 0.0 | 0.0 | |||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ARG | A:585 | A:543 | 0.0 | 0.0 | -77.0 | 108.8 | 0.0 | 0.0 | 0.0 | |||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:543 | A:543 | 0.0 | 0.0 | -75.7 | 96.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.578 |
O |
O |
|||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:543 | A:543 | 0.0 | 0.0 | -72.2 | 98.1 | 0.0 | 0.0 | 0.0 | |||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -72.0 | 103.3 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -74.2 | 109.3 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -70.7 | 104.6 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -72.2 | 120.1 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -73.6 | 103.2 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -76.4 | 120.4 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -70.6 | 118.9 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -72.5 | 123.1 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -73.2 | 118.3 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -73.5 | 107.5 | 0.0 | 0.0 | 0.0 | |||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -70.4 | 113.3 | 0.0 | 0.0 | 0.0 | |||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -74.7 | 114.8 | 0.0 | 0.0 | 0.0 | |||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -76.4 | 121.4 | 0.0 | 0.0 | 0.0 | |||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -70.8 | 116.4 | 0.0 | 0.0 | 0.0 | |||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -70.0 | 108.0 | 0.0 | 0.0 | 0.0 | |||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -72.2 | 106.3 | 0.0 | 0.0 | 0.0 | |||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:543 | A:543 | 0.0 | 0.0 | -67.3 | 116.2 | 0.0 | 0.0 | 0.0 | |||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:543 | A:543 | 0.0 | 0.0 | -67.0 | 117.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.457 |
NH2 |
O |
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| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:543 | A:543 | 0.0 | 0.0 | -69.1 | 97.8 | 0.0 | 0.0 | 0.0 | |||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:542 | A:542 | 0.0 | 0.0 | -85.1 | 94.2 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.666 6.155 |
N N |
O1 O |
|||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:542 | A:542 | 0.0 | 0.0 | -77.8 | 85.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.195 |
N |
O |
|||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:542 | A:542 | 0.0 | 0.0 | -78.4 | 96.9 | 0.0 | 0.0 | 0.0 |
UNL UNL UNL UNL HOH |
9.182 9.483 9.501 6.691 3.670 |
NH2 N NH2 C N |
O1 O1 O O O |
|||
| ARG | E:542 | N:542 | 0.0 | 0.0 | -79.9 | 99.2 | NA | NA | NA | ||||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:542 | A:542 | 0.0 | 0.0 | -76.3 | 97.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.832 |
N |
O |
|||
| ARG | E:542 | N:542 | 0.0 | 0.0 | -77.2 | 97.6 | NA | NA | NA | ||||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:542 | A:542 | 0.0 | 0.0 | -78.4 | 101.2 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.748 6.257 |
N C |
O1 O |
|||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ARG | A:542 | A:542 | 0.0 | 0.0 | -73.1 | 97.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.548 |
N |
O |
|||
| ARG | E:542 | N:542 | 0.0 | 0.0 | -72.9 | 96.6 | NA | NA | NA | ||||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -76.5 | 92.8 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.945 3.854 |
NH1 N |
S2 O |
|||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -68.6 | 103.4 | 0.0 | 0.0 | 0.0 |
UNL HOH |
7.473 3.611 |
NH2 N |
C1 O |
|||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -75.1 | 99.2 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.863 3.695 |
NH1 N |
S2 O |
|||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ARG | A:542 | A:542 | 0.0 | 0.0 | -73.5 | 96.3 | 0.0 | 0.0 | 0.0 |
UNL HOH |
9.854 7.707 |
NH2 CA |
S2 O |
|||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -67.4 | 104.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.234 |
CD |
O |
|||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -66.8 | 105.3 | 0.0 | 0.0 | 0.0 |
UNL UNL HOH |
9.476 6.149 5.840 |
NH1 C N |
S2 O2 O |
|||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:542 | A:542 | 0.0 | 0.0 | -75.7 | 94.9 | 0.0 | 0.0 | 0.0 |
UNL UNL UNL HOH |
9.949 6.367 9.195 3.873 |
NH1 C NH2 N |
S2 O2 O O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ARG | A:585 | A:585 | 0.0 | 0.0 | -69.1 | 98.0 | ||