Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251554 | . | C | A | CCDS3853.1:NM_004168.2:c.1765Cgg>Agg_NP_004159.2:p.589R>R | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ARG | A:557 | A:589 | 0.0 | 0.0 | B | -154.7 | 128.1 | 0.0 | 0.0 | 0.0 |
MLI GOL EDO EDO HOH |
8.261 6.892 3.672 6.645 7.254 |
NH1 O N NH2 CA |
O9 O1 O2 O1 O |
||
| ARG | C:557 | C:589 | 0.0 | 0.0 | B | -163.9 | 124.1 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ARG | A:589 | A:547 | 0.0 | 0.0 | B | -110.1 | 123.6 | 0.0 | 0.0 | 0.0 |
HOH |
9.270 |
NH2 |
O |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ARG | A:589 | A:547 | 0.0 | 0.0 | B | -131.2 | 136.8 | 0.0 | 0.0 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:547 | A:547 | 1.0 | 0.004 | B | -140.4 | 133.5 | 1.0 | 0.004 | 0.0 |
HOH |
6.890 |
NH2 |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:547 | A:547 | 1.0 | 0.004 | B | -138.9 | 130.5 | 1.0 | 0.004 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -137.3 | 113.1 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -142.3 | 117.2 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 1.0 | 0.004 | B | -142.1 | 125.0 | 1.0 | 0.004 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | -99.4 | 126.1 | 0.0 | 0.0 | 0.0 | |||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -134.4 | 116.6 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -132.6 | 105.2 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | E | -119.6 | 116.9 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | E | -121.9 | 113.8 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -132.9 | 119.6 | 0.0 | 0.0 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -142.6 | 115.5 | 0.0 | 0.0 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -118.3 | 128.3 | 0.0 | 0.0 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -136.7 | 117.8 | 0.0 | 0.0 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 1.0 | 0.004 | B | -140.0 | 124.3 | 1.0 | 0.004 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -136.9 | 112.4 | 0.0 | 0.0 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -122.2 | 129.3 | 0.0 | 0.0 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 3.0 | 0.013 | B | -149.3 | 127.7 | 3.0 | 0.013 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -131.0 | 115.8 | 0.0 | 0.0 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -122.3 | 129.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.483 |
O |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:547 | A:547 | 0.0 | 0.0 | B | -115.3 | 120.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.238 |
NH2 |
O |
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| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -148.6 | 134.2 | 2.0 | 0.009 | 0.0 |
HOH |
3.318 |
N |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -143.6 | 117.9 | 1.0 | 0.004 | 0.0 |
HOH |
3.846 |
N |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -146.3 | 125.9 | 2.0 | 0.009 | 0.0 |
AZI UNL HOH |
7.385 8.166 3.707 |
NH2 NH2 N |
N2 O1 O |
||
| ARG | E:546 | N:546 | 1.0 | 0.004 | B | -147.7 | 125.4 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -150.0 | 129.4 | 2.0 | 0.009 | 0.0 |
HOH |
3.371 |
N |
O |
||
| ARG | E:546 | N:546 | 2.0 | 0.009 | B | -151.4 | 127.1 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -147.3 | 118.3 | 1.0 | 0.004 | 0.0 |
HOH |
2.990 |
N |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -147.3 | 125.0 | 2.0 | 0.009 | 0.0 |
HOH |
3.580 |
N |
O |
||
| ARG | E:546 | N:546 | 1.0 | 0.004 | B | -146.9 | 125.0 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -142.1 | 134.0 | 1.0 | 0.004 | 0.0 |
UNL UNL UNL HOH |
6.962 8.585 4.834 4.062 |
NH2 NH1 CA CA |
O2 S2 O O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -146.8 | 121.5 | 1.0 | 0.004 | 0.0 |
UNL UNL UNL HOH |
6.888 8.638 7.818 3.598 |
NH2 NH2 CA N |
O2 S2 O O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -154.1 | 126.4 | 2.0 | 0.009 | 0.0 |
UNL UNL HOH |
8.422 6.932 3.303 |
NH2 NH1 N |
S2 C1 O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -141.7 | 124.8 | 1.0 | 0.004 | 0.0 |
UNL UNL HOH |
7.610 8.835 7.882 |
NH1 NH1 N |
O S2 O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 0.0 | 0.0 | B | -133.8 | 118.1 | 0.0 | 0.0 | 0.0 |
UNL UNL HOH |
6.723 8.591 7.293 |
NH2 NH2 O |
O1 S2 O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 1.0 | 0.004 | B | -145.0 | 119.2 | 1.0 | 0.004 | 0.0 |
UNL UNL UNL HOH |
8.341 9.312 6.828 3.978 |
NH2 NH2 NH2 CA |
S2 O1 O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:546 | A:546 | 2.0 | 0.009 | B | -153.4 | 125.4 | 2.0 | 0.009 | 0.0 |
UNL UNL UNL HOH |
8.585 9.882 6.813 3.141 |
NH2 NH2 NH1 N |
S2 O1 C1 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ARG | A:589 | A:589 | 2.0 | 0.009 | B | -146.4 | 129.3 | |