Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 251561 | . | C | A | CCDS3853.1:NM_004168.2:c.1772gCg>gAg_NP_004159.2:p.591A>E | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ALA | A:559 | A:591 | 19.0 | 0.165 | T | -76.9 | -9.7 | 19.0 | 0.165 | 0.0 |
GOL EDO HOH |
2.951 6.154 7.268 |
O N O |
O2 O2 O |
||
| ALA | C:559 | C:591 | 14.0 | 0.122 | T | -74.6 | -7.1 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ALA | A:591 | A:549 | 6.0 | 0.052 | T | -79.5 | -19.4 | 6.0 | 0.052 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ALA | A:591 | A:549 | 7.0 | 0.061 | T | -90.9 | -3.5 | 7.0 | 0.061 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:549 | A:549 | 6.0 | 0.052 | T | -65.6 | -28.0 | 6.0 | 0.052 | 0.0 |
HOH |
3.215 |
O |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ALA | A:549 | A:549 | 5.0 | 0.043 | T | -66.7 | -29.1 | 5.0 | 0.043 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 10.0 | 0.087 | T | -74.8 | -28.6 | 10.0 | 0.087 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 8.0 | 0.07 | T | -65.5 | -36.1 | 8.0 | 0.07 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 8.0 | 0.07 | T | -66.0 | -31.5 | 8.0 | 0.07 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 6.0 | 0.052 | T | -79.0 | -18.2 | 6.0 | 0.052 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 11.0 | 0.096 | T | -69.8 | -36.3 | 11.0 | 0.096 | 0.0 | ||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 7.0 | 0.061 | T | -66.6 | -35.8 | 7.0 | 0.061 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 5.0 | 0.043 | T | -70.3 | -18.4 | 5.0 | 0.043 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 5.0 | 0.043 | T | -69.0 | -40.6 | 5.0 | 0.043 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 7.0 | 0.061 | T | -73.8 | -29.8 | 7.0 | 0.061 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 5.0 | 0.043 | T | -76.8 | -32.3 | 5.0 | 0.043 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 9.0 | 0.078 | T | -77.6 | -29.2 | 9.0 | 0.078 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 8.0 | 0.07 | T | -72.9 | -25.7 | 8.0 | 0.07 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 6.0 | 0.052 | T | -76.6 | -34.8 | 6.0 | 0.052 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 8.0 | 0.07 | T | -69.0 | -39.1 | 8.0 | 0.07 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 4.0 | 0.035 | T | -76.2 | -23.9 | 4.0 | 0.035 | 0.0 | ||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 6.0 | 0.052 | T | -71.5 | -23.4 | 6.0 | 0.052 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ALA | A:549 | A:549 | 6.0 | 0.052 | T | -72.2 | -25.8 | 6.0 | 0.052 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:549 | A:549 | 5.0 | 0.043 | T | -71.0 | -33.1 | 5.0 | 0.043 | 0.0 |
HOH |
3.123 |
O |
O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ALA | A:549 | A:549 | 7.0 | 0.061 | T | -68.2 | -30.0 | 7.0 | 0.061 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:548 | A:548 | 7.0 | 0.061 | T | -71.2 | -8.5 | 7.0 | 0.061 | 0.0 |
HOH |
2.604 |
O |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:548 | A:548 | 5.0 | 0.043 | T | -74.8 | -23.5 | 5.0 | 0.043 | 0.0 |
HOH |
2.579 |
O |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ALA | A:548 | A:548 | 8.0 | 0.07 | T | -69.6 | -12.3 | 8.0 | 0.07 | 0.0 |
HOH |
2.743 |
O |
O |
||
| ALA | E:548 | N:548 | 6.0 | 0.052 | T | -71.7 | -10.6 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:548 | A:548 | 7.0 | 0.061 | T | -66.3 | -13.5 | 7.0 | 0.061 | 0.0 |
HOH |
2.792 |
O |
O |
||
| ALA | E:548 | N:548 | 6.0 | 0.052 | T | -66.6 | -14.2 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ALA | A:548 | A:548 | 5.0 | 0.043 | T | -76.9 | 7.0 | 5.0 | 0.043 | 0.0 |
HOH |
2.931 |
O |
O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ALA | A:548 | A:548 | 6.0 | 0.052 | T | -66.5 | -14.9 | 6.0 | 0.052 | 0.0 |
HOH |
2.767 |
O |
O |
||
| ALA | E:548 | N:548 | 7.0 | 0.061 | T | -65.8 | -15.5 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 7.0 | 0.061 | T | -71.2 | -9.2 | 7.0 | 0.061 | 0.0 |
UNL HOH |
7.810 2.625 |
N O |
O O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 6.0 | 0.052 | T | -77.9 | -12.5 | 6.0 | 0.052 | 0.0 |
HOH |
2.543 |
O |
O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 6.0 | 0.052 | T | -71.8 | -12.4 | 6.0 | 0.052 | 0.0 |
HOH |
2.695 |
O |
O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ALA | A:548 | A:548 | 6.0 | 0.052 | T | -67.5 | -24.1 | 6.0 | 0.052 | 0.0 | ||||||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 8.0 | 0.07 | T | -72.8 | -40.3 | 8.0 | 0.07 | 0.0 |
HOH |
2.997 |
O |
O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 6.0 | 0.052 | T | -77.0 | -14.9 | 6.0 | 0.052 | 0.0 |
HOH |
2.710 |
O |
O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ALA | A:548 | A:548 | 7.0 | 0.061 | T | -76.4 | -4.9 | 7.0 | 0.061 | 0.0 |
HOH |
2.853 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ALA | A:591 | A:591 | 8.0 | 0.07 | T | -74.5 | -10.5 | |