Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 254526 . G A CCDS3853.1:NM_004168.2:c.1813Gat>Aat_NP_004159.2:p.605D>N Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 ASP A:573 A:605 78.0 0.52 -91.3 96.7 78.0 0.52 0.0 EDO
HOH
 3.435
8.274
 N
OD1
 O2
O
ASP C:573 C:605 62.0 0.413 -98.1 90.4 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 ASP A:605 A:563 89.0 0.593 -75.2 96.2 89.0 0.593 0.0
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 ASP A:605 A:563 83.0 0.553 -116.0 97.5 83.0 0.553 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 ASP A:563 A:563 61.0 0.407 -107.5 90.1 61.0 0.407 0.0 HOH
 3.027
 N
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 ASP A:563 A:563 60.0 0.4 -108.2 85.3 60.0 0.4 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 84.0 0.56 -82.5 88.1 84.0 0.56 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 78.0 0.52 -80.2 91.6 78.0 0.52 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 84.0 0.56 -79.1 108.7 84.0 0.56 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 78.0 0.52 -87.9 97.6 78.0 0.52 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 72.0 0.48 -86.1 91.4 72.0 0.48 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 88.0 0.587 -86.0 99.4 88.0 0.587 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 86.0 0.573 -83.9 94.7 86.0 0.573 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 91.0 0.607 -88.4 96.3 91.0 0.607 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 80.0 0.533 -82.1 90.1 80.0 0.533 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 80.0 0.533 -88.3 92.5 80.0 0.533 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 87.0 0.58 -89.1 90.2 87.0 0.58 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 88.0 0.587 -88.9 96.5 88.0 0.587 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 81.0 0.54 -82.3 91.8 81.0 0.54 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 80.0 0.533 -85.2 91.4 80.0 0.533 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 85.0 0.567 -97.6 93.3 85.0 0.567 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 70.0 0.467 -83.3 97.1 70.0 0.467 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:563 A:563 91.0 0.607 -84.1 106.4 91.0 0.607 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ASP A:563 A:563 77.0 0.513 -113.1 88.1 77.0 0.513 0.0 HOH
 4.142
 OD2
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ASP A:563 A:563 78.0 0.52 -112.1 97.5 78.0 0.52 0.0 HOH
 3.926
 CA
 O
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 ASP A:562 A:562 45.0 0.3 -93.7 97.3 45.0 0.3 0.0 HOH
 3.649
 OD2
 O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 ASP A:562 A:562 56.0 0.373 -87.5 102.4 56.0 0.373 0.0 HOH
 3.603
 CA
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 ASP A:562 A:562 45.0 0.3 -96.9 96.7 45.0 0.3 0.0 AZI
UNL
HOH
 3.974
5.337
2.779
 C
O
OD2
 N3
O
O
ASP E:562 N:562 45.0 0.3 -94.9 97.1 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ASP A:562 A:562 44.0 0.293 -92.2 100.5 44.0 0.293 0.0 HOH
 3.841
 C
 O
ASP E:562 N:562 44.0 0.293 -90.6 99.9 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ASP A:562 A:562 63.0 0.42 -98.1 99.9 63.0 0.42 0.0 HOH
 3.228
 OD2
 O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 ASP A:562 A:562 44.0 0.293 -95.7 96.5 44.0 0.293 0.0 UNL
HOH
 8.366
3.471
 O
CG
 C2
O
ASP E:562 N:562 43.0 0.287 -95.5 96.2 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 64.0 0.427 -83.3 88.9 64.0 0.427 0.0 UNL
HOH
 3.995
4.194
 C
CA
 O3
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 68.0 0.453 -84.6 85.1 68.0 0.453 0.0 UNL
UNL
HOH
 3.993
9.394
9.743
 OD1
OD1
N
 O3
O
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 53.0 0.353 -85.8 98.5 53.0 0.353 0.0 UNL
HOH
 3.816
3.990
 OD1
CA
 O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 ASP A:562 A:562 62.0 0.413 -89.1 97.0 62.0 0.413 0.0 UNL
 4.226
 OD1
 O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 52.0 0.347 -120.4 92.6 52.0 0.347 0.0 UNL
 3.235
 OD1
 O2
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 45.0 0.3 -84.7 89.4 45.0 0.3 0.0 UNL
HOH
 3.856
7.713
 CA
O
 O
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:562 A:562 46.0 0.307 -85.4 97.3 46.0 0.307 0.0 UNL
HOH
 3.935
3.838
 OD1
CA
 O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 ASP A:605 A:605 57.0 0.38 -84.1 89.4