Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 254559 | . | A | C | CCDS3853.1:NM_004168.2:c.1846Aag>Cag_NP_004159.2:p.616K>Q | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | LYS | A:584 | A:616 | 76.0 | 0.38 | -65.9 | 141.4 | 76.0 | 0.38 | 0.0 |
MLI EDO HOH |
5.520 3.470 9.982 |
O CD O |
O6 O2 O |
|||
LYS | C:584 | C:616 | 72.0 | 0.36 | -70.4 | 150.7 | NA | NA | NA | ||||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | LYS | A:616 | A:574 | 68.0 | 0.34 | -81.7 | 142.1 | 68.0 | 0.34 | 0.0 |
HOH |
8.816 |
O |
O |
|||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | LYS | A:616 | A:574 | 69.0 | 0.345 | -79.5 | 141.2 | 69.0 | 0.345 | 0.0 | |||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | LYS | A:574 | A:574 | 63.0 | 0.315 | -70.1 | 147.3 | 63.0 | 0.315 | 0.0 |
HOH |
2.744 |
NZ |
O |
|||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | LYS | A:574 | A:574 | 68.0 | 0.34 | -72.6 | 148.9 | 68.0 | 0.34 | 0.0 | |||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 71.0 | 0.355 | -82.0 | 135.5 | 71.0 | 0.355 | 0.0 | |||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 72.0 | 0.36 | -91.0 | 132.9 | 72.0 | 0.36 | 0.0 | |||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 69.0 | 0.345 | -73.1 | 135.5 | 69.0 | 0.345 | 0.0 | |||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 72.0 | 0.36 | -67.7 | 140.0 | 72.0 | 0.36 | 0.0 | |||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 71.0 | 0.355 | -86.8 | 145.9 | 71.0 | 0.355 | 0.0 | |||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 79.0 | 0.395 | -81.9 | 150.4 | 79.0 | 0.395 | 0.0 | |||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 103.0 | 0.515 | -92.4 | 140.6 | 103.0 | 0.515 | 0.0 | |||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 104.0 | 0.52 | -94.1 | 147.4 | 104.0 | 0.52 | 0.0 | |||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 78.0 | 0.39 | -75.3 | 139.7 | 78.0 | 0.39 | 0.0 | |||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 87.0 | 0.435 | -74.3 | 146.0 | 87.0 | 0.435 | 0.0 | |||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 68.0 | 0.34 | -73.2 | 138.9 | 68.0 | 0.34 | 0.0 | |||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 90.0 | 0.45 | -72.0 | 139.4 | 90.0 | 0.45 | 0.0 | |||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 81.0 | 0.405 | -69.9 | 136.1 | 81.0 | 0.405 | 0.0 | |||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 76.0 | 0.38 | -77.5 | 137.8 | 76.0 | 0.38 | 0.0 | |||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 83.0 | 0.415 | -84.5 | 142.9 | 83.0 | 0.415 | 0.0 | |||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 69.0 | 0.345 | -74.2 | 136.9 | 69.0 | 0.345 | 0.0 | |||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | LYS | A:574 | A:574 | 63.0 | 0.315 | -75.7 | 136.3 | 63.0 | 0.315 | 0.0 | |||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | LYS | A:574 | A:574 | 75.0 | 0.375 | -76.3 | 146.0 | 75.0 | 0.375 | 0.0 |
HOH |
7.112 |
NZ |
O |
|||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | LYS | A:574 | A:574 | 83.0 | 0.415 | -63.9 | 142.5 | 83.0 | 0.415 | 0.0 |
HOH |
5.030 |
NZ |
O |
|||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:573 | A:573 | 90.0 | 0.4 | -83.2 | 151.3 | 90.0 | 0.4 | 0.0 |
HOH |
2.458 |
NH2 |
O |
|||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:573 | A:573 | 97.0 | 0.431 | -74.5 | 149.5 | 97.0 | 0.431 | 0.0 |
HOH |
3.340 |
NH1 |
O |
|||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:573 | A:573 | 92.0 | 0.409 | -74.2 | 135.1 | 92.0 | 0.409 | 0.0 |
AZI UNL UNL HOH |
6.150 6.124 9.473 2.884 |
NH1 O CD NH1 |
N3 S2 O O |
|||
ARG | E:573 | N:573 | 89.0 | 0.396 | -74.5 | 134.0 | NA | NA | NA | ||||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:573 | A:573 | 84.0 | 0.373 | -74.7 | 137.7 | 84.0 | 0.373 | 0.0 |
HOH |
2.711 |
NH2 |
O |
|||
ARG | E:573 | N:573 | 82.0 | 0.364 | -73.7 | 138.1 | NA | NA | NA | ||||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:573 | A:573 | 82.0 | 0.364 | -66.0 | 156.6 | 82.0 | 0.364 | 0.0 |
HOH |
3.436 |
NH2 |
O |
|||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ARG | A:573 | A:573 | 87.0 | 0.387 | -81.2 | 138.6 | 87.0 | 0.387 | 0.0 |
HOH |
2.833 |
CD |
O |
|||
ARG | E:573 | N:573 | 89.0 | 0.396 | -81.3 | 138.7 | NA | NA | NA | ||||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 91.0 | 0.404 | -71.8 | 137.1 | 91.0 | 0.404 | 0.0 |
UNL UNL HOH |
4.516 5.846 2.502 |
NH1 O NH1 |
O2 O1 O |
|||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 90.0 | 0.4 | -76.0 | 135.8 | 90.0 | 0.4 | 0.0 |
UNL UNL HOH |
4.355 6.122 4.617 |
NH1 O O |
O3 O1 O |
|||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 89.0 | 0.396 | -89.6 | 140.2 | 89.0 | 0.396 | 0.0 |
UNL UNL UNL HOH |
5.813 5.943 4.094 2.787 |
O NH1 O NH1 |
O1 O O O |
|||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ARG | A:573 | A:573 | 91.0 | 0.404 | -74.5 | 134.7 | 91.0 | 0.404 | 0.0 |
UNL UNL HOH |
7.044 5.862 8.235 |
NH1 O NH2 |
O O1 O |
|||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 87.0 | 0.387 | -72.5 | 133.7 | 87.0 | 0.387 | 0.0 |
UNL UNL |
4.498 5.828 |
NH1 O |
O2 O1 |
|||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 85.0 | 0.378 | -69.8 | 137.6 | 85.0 | 0.378 | 0.0 |
UNL UNL UNL HOH |
7.076 6.901 5.032 5.877 |
O CD NH1 O |
C1 O1 O O |
|||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:573 | A:573 | 87.0 | 0.387 | -78.3 | 138.9 | 87.0 | 0.387 | 0.0 |
UNL UNL UNL UNL UNL HOH |
5.766 7.342 5.595 4.306 9.687 2.925 |
O CD NH1 O O NH1 |
O1 O1 O O O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | LYS | A:616 | A:616 | 79.0 | 0.395 | -66.4 | 140.2 |