Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 254599 | . | A | C | CCDS3853.1:NM_004168.2:c.1886tAt>tCt_NP_004159.2:p.629Y>S | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | TYR | A:597 | A:629 | 40.0 | 0.174 | E | -123.3 | 155.6 | 40.0 | 0.174 | 0.0 |
EDO HOH |
3.928 2.823 |
CG OH |
C1 O |
||
| TYR | C:597 | C:629 | 39.0 | 0.17 | E | -124.9 | 157.7 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | TYR | A:629 | A:587 | 39.0 | 0.17 | E | -119.3 | 173.7 | 39.0 | 0.17 | 0.0 |
HOH |
3.552 |
CB |
O |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | TYR | A:629 | A:587 | 40.0 | 0.174 | E | -120.0 | 170.3 | 40.0 | 0.174 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:587 | A:587 | 40.0 | 0.174 | E | -134.9 | 175.7 | 40.0 | 0.174 | 0.0 |
HOH |
2.739 |
OH |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:587 | A:587 | 40.0 | 0.174 | E | -132.0 | 178.8 | 40.0 | 0.174 | 0.0 | ||||||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 43.0 | 0.187 | E | -123.9 | 160.2 | 43.0 | 0.187 | 0.0 | ||||||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 41.0 | 0.178 | E | -125.5 | 165.5 | 41.0 | 0.178 | 0.0 | ||||||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 48.0 | 0.209 | E | -122.8 | 148.0 | 48.0 | 0.209 | 0.0 | ||||||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 42.0 | 0.183 | E | -116.6 | 158.7 | 42.0 | 0.183 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 43.0 | 0.187 | -120.7 | 164.7 | 43.0 | 0.187 | 0.0 | |||||||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 41.0 | 0.178 | E | -125.5 | 159.7 | 41.0 | 0.178 | 0.0 | ||||||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 44.0 | 0.191 | E | -113.8 | 160.1 | 44.0 | 0.191 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 39.0 | 0.17 | E | -112.7 | 160.8 | 39.0 | 0.17 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 47.0 | 0.204 | E | -110.9 | 145.0 | 47.0 | 0.204 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 45.0 | 0.196 | E | -105.8 | 153.5 | 45.0 | 0.196 | 0.0 | ||||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 39.0 | 0.17 | E | -112.4 | 156.5 | 39.0 | 0.17 | 0.0 | ||||||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 41.0 | 0.178 | E | -124.4 | 151.7 | 41.0 | 0.178 | 0.0 | ||||||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 47.0 | 0.204 | E | -114.8 | 166.6 | 47.0 | 0.204 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 42.0 | 0.183 | E | -117.9 | 160.4 | 42.0 | 0.183 | 0.0 | ||||||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 38.0 | 0.165 | -120.7 | 168.0 | 38.0 | 0.165 | 0.0 | |||||||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 44.0 | 0.191 | E | -120.4 | 159.2 | 44.0 | 0.191 | 0.0 | ||||||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:587 | A:587 | 36.0 | 0.157 | E | -118.3 | 162.9 | 36.0 | 0.157 | 0.0 | ||||||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:587 | A:587 | 40.0 | 0.174 | -128.5 | 173.5 | 40.0 | 0.174 | 0.0 |
HOH |
6.895 |
O |
O |
|||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:587 | A:587 | 46.0 | 0.2 | E | -127.9 | 172.7 | 46.0 | 0.2 | 0.0 | ||||||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:586 | A:586 | 42.0 | 0.183 | E | -130.3 | 145.9 | 42.0 | 0.183 | 0.0 |
HOH |
2.609 |
OH |
O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:586 | A:586 | 42.0 | 0.183 | E | -136.5 | 156.0 | 42.0 | 0.183 | 0.0 |
HOH |
2.690 |
OH |
O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:586 | A:586 | 46.0 | 0.2 | E | -128.6 | 153.0 | 46.0 | 0.2 | 0.0 |
UNL HOH |
8.439 3.371 |
CE1 CA |
O O |
||
| TYR | E:586 | N:586 | 46.0 | 0.2 | E | -130.6 | 151.7 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:586 | A:586 | 49.0 | 0.213 | E | -135.7 | 150.6 | 49.0 | 0.213 | 0.0 |
HOH |
3.522 |
CA |
O |
||
| TYR | E:586 | N:586 | 47.0 | 0.204 | E | -135.6 | 150.2 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:586 | A:586 | 39.0 | 0.17 | E | -132.9 | 147.5 | 39.0 | 0.17 | 0.0 |
UNL HOH |
7.076 3.552 |
CD2 CE2 |
O1 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | TYR | A:586 | A:586 | 44.0 | 0.191 | E | -136.9 | 153.1 | 44.0 | 0.191 | 0.0 |
UNL HOH |
8.307 2.488 |
O OH |
C2 O |
||
| TYR | E:586 | N:586 | 43.0 | 0.187 | E | -136.6 | 153.7 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 31.0 | 0.135 | E | -133.3 | 147.4 | 31.0 | 0.135 | 0.0 |
HOH |
3.371 |
CD2 |
O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 43.0 | 0.187 | E | -129.4 | 150.6 | 43.0 | 0.187 | 0.0 |
UNL HOH |
6.362 3.154 |
N OH |
O O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 46.0 | 0.2 | E | -132.5 | 150.0 | 46.0 | 0.2 | 0.0 |
MOH UNL HOH |
9.983 3.717 3.639 |
O CG CA |
O O1 O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | TYR | A:586 | A:586 | 44.0 | 0.191 | E | -129.2 | 159.3 | 44.0 | 0.191 | 0.0 |
HOH |
3.885 |
CA |
O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 47.0 | 0.204 | E | -120.9 | 157.1 | 47.0 | 0.204 | 0.0 | ||||||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 48.0 | 0.209 | E | -129.8 | 153.1 | 48.0 | 0.209 | 0.0 |
UNL UNL HOH |
8.915 3.326 3.832 |
O CE2 CA |
O2 O1 O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:586 | A:586 | 48.0 | 0.209 | E | -128.1 | 153.0 | 48.0 | 0.209 | 0.0 |
UNL UNL HOH |
8.377 3.680 3.271 |
O CG CA |
O3 O1 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | TYR | A:629 | A:629 | 46.0 | 0.2 | E | -124.6 | 152.1 | |