Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 256459 | . | A | C | CCDS3853.1:NM_004168.2:c.1919gAa>gCa_NP_004159.2:p.640E>A | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLU | A:608 | A:640 | 72.0 | 0.379 | E | -125.7 | 177.4 | 72.0 | 0.379 | 0.0 |
EDO HOH |
3.724 4.938 |
OE2 OE1 |
O1 O |
||
GLU | C:608 | C:640 | 70.0 | 0.368 | E | -128.4 | 178.2 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLU | A:640 | A:598 | 82.0 | 0.432 | E | -116.5 | -161.4 | 82.0 | 0.432 | 0.0 |
HOH |
9.372 |
OE1 |
O |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLU | A:640 | A:598 | 89.0 | 0.468 | E | -147.6 | -173.7 | 89.0 | 0.468 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:598 | A:598 | 93.0 | 0.489 | E | -141.3 | -169.3 | 93.0 | 0.489 | 0.0 |
HOH |
4.428 |
OE1 |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:598 | A:598 | 94.0 | 0.495 | E | -141.1 | -172.1 | 94.0 | 0.495 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 94.0 | 0.495 | E | -137.8 | -179.7 | 94.0 | 0.495 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 81.0 | 0.426 | E | -110.9 | -173.5 | 81.0 | 0.426 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 89.0 | 0.468 | E | -139.7 | -179.4 | 89.0 | 0.468 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 75.0 | 0.395 | E | -136.1 | -178.0 | 75.0 | 0.395 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 90.0 | 0.474 | E | -124.2 | -170.7 | 90.0 | 0.474 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 77.0 | 0.405 | E | -125.7 | -166.9 | 77.0 | 0.405 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 81.0 | 0.426 | E | -124.4 | -176.8 | 81.0 | 0.426 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 87.0 | 0.458 | E | -105.9 | 177.3 | 87.0 | 0.458 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 79.0 | 0.416 | E | -142.1 | 170.6 | 79.0 | 0.416 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 87.0 | 0.458 | E | -139.0 | -177.0 | 87.0 | 0.458 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 85.0 | 0.447 | E | -124.0 | 171.7 | 85.0 | 0.447 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 88.0 | 0.463 | E | -132.9 | -179.4 | 88.0 | 0.463 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 73.0 | 0.384 | E | -121.6 | -176.0 | 73.0 | 0.384 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 86.0 | 0.453 | E | -132.9 | -171.4 | 86.0 | 0.453 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 87.0 | 0.458 | E | -116.8 | -170.0 | 87.0 | 0.458 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 87.0 | 0.458 | E | -146.6 | 178.6 | 87.0 | 0.458 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:598 | A:598 | 81.0 | 0.426 | E | -118.0 | -177.2 | 81.0 | 0.426 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:598 | A:598 | 77.0 | 0.405 | E | -152.9 | -163.8 | 77.0 | 0.405 | 0.0 |
HOH |
7.064 |
O |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:598 | A:598 | 90.0 | 0.474 | E | -143.6 | -176.6 | 90.0 | 0.474 | 0.0 | ||||||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:597 | A:597 | 106.0 | 0.53 | E | -147.8 | 174.9 | 106.0 | 0.53 | 0.0 |
HOH |
2.892 |
CE |
O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:597 | A:597 | 102.0 | 0.51 | E | -153.3 | 170.8 | 102.0 | 0.51 | 0.0 |
HOH |
2.940 |
CE |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | LYS | A:597 | A:597 | 72.0 | 0.36 | E | -134.6 | 175.4 | 72.0 | 0.36 | 0.0 |
UNL UNL HOH |
4.015 5.476 4.705 |
CA C N |
O O O |
||
LYS | E:597 | N:597 | 70.0 | 0.35 | E | -135.8 | 174.0 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | LYS | A:597 | A:597 | 70.0 | 0.35 | E | -136.3 | 173.1 | 70.0 | 0.35 | 0.0 |
HOH |
3.392 |
NZ |
O |
||
LYS | E:597 | N:597 | 69.0 | 0.345 | E | -135.7 | 174.9 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | LYS | A:597 | A:597 | 102.0 | 0.51 | E | -151.4 | 172.4 | 102.0 | 0.51 | 0.0 |
HOH |
3.251 |
NZ |
O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | LYS | A:597 | A:597 | 104.0 | 0.52 | E | -135.1 | 172.2 | 104.0 | 0.52 | 0.0 |
HOH |
3.661 |
CE |
O |
||
LYS | E:597 | N:597 | 103.0 | 0.515 | E | -136.3 | 171.1 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 100.0 | 0.5 | E | -127.6 | 174.2 | 100.0 | 0.5 | 0.0 |
HOH |
5.532 |
NZ |
O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 116.0 | 0.58 | E | -136.1 | 173.8 | 116.0 | 0.58 | 0.0 |
UNL UNL UNL HOH |
6.747 6.281 5.880 2.830 |
O CB C NZ |
C2 O O O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 71.0 | 0.355 | E | -132.5 | 178.1 | 71.0 | 0.355 | 0.0 |
UNL UNL HOH |
4.614 7.984 4.438 |
CD CE CE |
O2 O O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | LYS | A:597 | A:597 | 76.0 | 0.38 | E | -131.3 | -170.5 | 76.0 | 0.38 | 0.0 |
HOH |
7.644 |
O |
O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 79.0 | 0.395 | E | -130.1 | 176.9 | 79.0 | 0.395 | 0.0 | ||||||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 70.0 | 0.35 | E | -129.6 | 177.5 | 70.0 | 0.35 | 0.0 |
UNL HOH |
3.419 3.949 |
CD CB |
O2 O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | LYS | A:597 | A:597 | 70.0 | 0.35 | E | -141.6 | 177.6 | 70.0 | 0.35 | 0.0 |
UNL UNL UNL HOH |
4.635 8.079 6.182 4.131 |
CD CE C CE |
O2 O O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLU | A:640 | A:640 | 83.0 | 0.437 | E | -128.8 | 176.3 |