Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 256459 . A C CCDS3853.1:NM_004168.2:c.1919gAa>gCa_NP_004159.2:p.640E>A Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
2020-08-26 GLU A:608 A:640 72.0 0.379 E -125.7 177.4 72.0 0.379 0.0 EDO
HOH
3.724
4.938
OE2
OE1
O1
O
GLU C:608 C:640 70.0 0.368 E -128.4 178.2 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
2015-08-05 GLU A:640 A:598 82.0 0.432 E -116.5 -161.4 82.0 0.432 0.0 HOH
9.372
OE1
O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
2016-03-02 GLU A:640 A:598 89.0 0.468 E -147.6 -173.7 89.0 0.468 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
2005-07-12 GLU A:598 A:598 93.0 0.489 E -141.3 -169.3 93.0 0.489 0.0 HOH
4.428
OE1
O
1zp0 1 ? 96.3 0.0 X-RAY
2005-07-12 GLU A:598 A:598 94.0 0.495 E -141.1 -172.1 94.0 0.495 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 94.0 0.495 E -137.8 -179.7 94.0 0.495 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 81.0 0.426 E -110.9 -173.5 81.0 0.426 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 89.0 0.468 E -139.7 -179.4 89.0 0.468 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 75.0 0.395 E -136.1 -178.0 75.0 0.395 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 90.0 0.474 E -124.2 -170.7 90.0 0.474 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 77.0 0.405 E -125.7 -166.9 77.0 0.405 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 81.0 0.426 E -124.4 -176.8 81.0 0.426 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 87.0 0.458 E -105.9 177.3 87.0 0.458 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 79.0 0.416 E -142.1 170.6 79.0 0.416 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 87.0 0.458 E -139.0 -177.0 87.0 0.458 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 85.0 0.447 E -124.0 171.7 85.0 0.447 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 88.0 0.463 E -132.9 -179.4 88.0 0.463 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 73.0 0.384 E -121.6 -176.0 73.0 0.384 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 86.0 0.453 E -132.9 -171.4 86.0 0.453 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 87.0 0.458 E -116.8 -170.0 87.0 0.458 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 87.0 0.458 E -146.6 178.6 87.0 0.458 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
2011-02-09 GLU A:598 A:598 81.0 0.426 E -118.0 -177.2 81.0 0.426 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
2011-09-07 GLU A:598 A:598 77.0 0.405 E -152.9 -163.8 77.0 0.405 0.0 HOH
7.064
O
O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
2011-09-07 GLU A:598 A:598 90.0 0.474 E -143.6 -176.6 90.0 0.474 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
2005-12-20 LYS A:597 A:597 106.0 0.53 E -147.8 174.9 106.0 0.53 0.0 HOH
2.892
CE
O
1yq4 1 50736125 91.79 0.0 X-RAY
2005-12-20 LYS A:597 A:597 102.0 0.51 E -153.3 170.8 102.0 0.51 0.0 HOH
2.940
CE
O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
2005-12-20 LYS A:597 A:597 72.0 0.36 E -134.6 175.4 72.0 0.36 0.0 UNL
UNL
HOH
4.015
5.476
4.705
CA
C
N
O
O
O
LYS E:597 N:597 70.0 0.35 E -135.8 174.0 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
2006-06-20 LYS A:597 A:597 70.0 0.35 E -136.3 173.1 70.0 0.35 0.0 HOH
3.392
NZ
O
LYS E:597 N:597 69.0 0.345 E -135.7 174.9 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
2006-06-20 LYS A:597 A:597 102.0 0.51 E -151.4 172.4 102.0 0.51 0.0 HOH
3.251
NZ
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
2010-08-25 LYS A:597 A:597 104.0 0.52 E -135.1 172.2 104.0 0.52 0.0 HOH
3.661
CE
O
LYS E:597 N:597 103.0 0.515 E -136.3 171.1 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 100.0 0.5 E -127.6 174.2 100.0 0.5 0.0 HOH
5.532
NZ
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 116.0 0.58 E -136.1 173.8 116.0 0.58 0.0 UNL
UNL
UNL
HOH
6.747
6.281
5.880
2.830
O
CB
C
NZ
C2
O
O
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 71.0 0.355 E -132.5 178.1 71.0 0.355 0.0 UNL
UNL
HOH
4.614
7.984
4.438
CD
CE
CE
O2
O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
2019-10-16 LYS A:597 A:597 76.0 0.38 E -131.3 -170.5 76.0 0.38 0.0 HOH
7.644
O
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 79.0 0.395 E -130.1 176.9 79.0 0.395 0.0
6myt 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 70.0 0.35 E -129.6 177.5 70.0 0.35 0.0 UNL
HOH
3.419
3.949
CD
CB
O2
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
2019-11-06 LYS A:597 A:597 70.0 0.35 E -141.6 177.6 70.0 0.35 0.0 UNL
UNL
UNL
HOH
4.635
8.079
6.182
4.131
CD
CE
C
CE
O2
O
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 GLU A:640 A:640 83.0 0.437 E -128.8 176.3