Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 256476 . G A CCDS3853.1:NM_004168.2:c.1936Gac>Aac_NP_004159.2:p.646D>N Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 ASP A:614 A:646 45.0 0.3 -95.9 -21.9 45.0 0.3 0.0 MLI
HOH
 3.228
4.462
 OD2
O
 O9
O
ASP C:614 C:646 43.0 0.287 -86.8 -25.4 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 ASP A:646 A:604 42.0 0.28 -107.8 -30.1 42.0 0.28 0.0 HOH
 3.983
 OD1
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 ASP A:646 A:604 47.0 0.313 -122.5 -40.7 47.0 0.313 0.0
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 ASP A:604 A:604 46.0 0.307 -102.4 -23.8 46.0 0.307 0.0 HOH
 2.706
 OD2
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 ASP A:604 A:604 45.0 0.3 -101.0 -25.5 45.0 0.3 0.0
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 48.0 0.32 -98.7 -33.3 48.0 0.32 0.0
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 48.0 0.32 -104.5 -23.9 48.0 0.32 0.0
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 47.0 0.313 -101.4 -33.6 47.0 0.313 0.0
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 51.0 0.34 -105.2 -37.9 51.0 0.34 0.0
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 44.0 0.293 -93.3 -34.6 44.0 0.293 0.0
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 46.0 0.307 -105.5 -16.6 46.0 0.307 0.0
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 59.0 0.393 -103.0 -35.6 59.0 0.393 0.0
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 50.0 0.333 -102.1 -32.8 50.0 0.333 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 51.0 0.34 -102.4 -32.7 51.0 0.34 0.0
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 57.0 0.38 -92.9 -35.6 57.0 0.38 0.0
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 51.0 0.34 -102.4 -31.1 51.0 0.34 0.0
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 43.0 0.287 -91.8 -40.1 43.0 0.287 0.0
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 52.0 0.347 -99.6 -37.2 52.0 0.347 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 52.0 0.347 -101.9 -40.1 52.0 0.347 0.0
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 45.0 0.3 -107.3 -32.4 45.0 0.3 0.0
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 53.0 0.353 -95.5 -39.9 53.0 0.353 0.0
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 ASP A:604 A:604 48.0 0.32 -95.4 -26.3 48.0 0.32 0.0
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ASP A:604 A:604 46.0 0.307 -106.1 -29.7 46.0 0.307 0.0
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 ASP A:604 A:604 43.0 0.287 -115.0 -31.6 43.0 0.287 0.0
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 ASP A:603 A:603 47.0 0.313 -94.3 -21.1 47.0 0.313 0.0 UNL
UNL
HOH
 3.280
8.768
2.724
 N
O
OD1
 O1
O1
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 ASP A:603 A:603 40.0 0.267 -92.9 -17.0 40.0 0.267 0.0 HOH
 4.441
 OD2
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 ASP A:603 A:603 47.0 0.313 -92.2 -18.9 47.0 0.313 0.0 UNL
HOH
 5.133
2.734
 OD2
OD2
 C1
O
ASP E:603 N:603 47.0 0.313 -93.7 -19.6 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ASP A:603 A:603 49.0 0.327 -90.9 -19.9 49.0 0.327 0.0 HOH
 2.905
 OD2
 O
ASP E:603 N:603 49.0 0.327 -90.5 -21.3 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 ASP A:603 A:603 41.0 0.273 -104.0 -12.3 41.0 0.273 0.0 UNL
UNL
UNL
HOH
 3.217
8.809
9.420
4.728
 N
O
O
O
 O1
O1
O1
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 ASP A:603 A:603 47.0 0.313 -95.4 -22.8 47.0 0.313 0.0 UNL
HOH
 9.310
2.764
 OD2
OD1
 C2
O
ASP E:603 N:603 45.0 0.3 -95.2 -22.7 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 42.0 0.28 -101.4 -16.5 42.0 0.28 0.0 UNL
HOH
 4.768
2.598
 OD2
OD1
 S2
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 55.0 0.367 -99.5 -14.0 55.0 0.367 0.0 UNL
UNL
UNL
HOH
 4.203
8.425
8.140
2.324
 OD2
N
C
OD2
 C2
N3
C1
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 49.0 0.327 -99.1 -21.1 49.0 0.327 0.0 UNL
UNL
UNL
HOH
 4.287
8.188
6.971
2.841
 OD2
OD2
O
OD1
 C2
O
O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 ASP A:603 A:603 45.0 0.3 -95.4 -18.5 45.0 0.3 0.0 UNL
UNL
HOH
 4.733
3.072
2.833
 OD2
N
OD1
 C2
O
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 45.0 0.3 -90.3 -13.4 45.0 0.3 0.0 UNL
HOH
 4.771
4.995
 OD2
O
 S2
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 51.0 0.34 -95.4 -19.2 51.0 0.34 0.0 UNL
HOH
 3.879
3.317
 OD2
OD1
 C2
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 ASP A:603 A:603 43.0 0.287 -103.2 -19.0 43.0 0.287 0.0 UNL
UNL
UNL
UNL
HOH
 4.903
8.493
6.773
2.801
2.731
 OD2
OD2
O
N
OD1
 C2
O
O
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 ASP A:646 A:646 42.0 0.28 -77.1 -26.9