Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 35871255 . T A CCDS3911.1:NM_002185.3:c.477taT>taA_NP_002176.2:p.159Y>* Homo sapiens interleukin 7 receptor (IL7R), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5j11 2 D6RGV2 100.0 7e-163 X-RAY
 2017-04-05 TYR B:160 B:159 122.0 0.53 S -82.7 -75.2 24.0 0.104 0.426 A:Q969D9:0.426
 HOH
 6.608
 HB3
 O
3di2 2 P16871 99.54 2e-162 X-RAY
 2009-01-27 TYR B:143 B:139 114.0 0.496 S -96.9 -78.6 18.0 0.078 0.418 A:P13232:0.417
 HOH
 2.597
 OH
 O
TYR D:143 D:139 114.0 0.496 S -94.6 -81.3 NA NA NA
3di3 2 P16871 99.54 2e-162 X-RAY
 2009-01-27 TYR B:143 B:139 102.0 0.443 S -101.1 -82.5 16.0 0.07 0.373 A:P13232:0.374
3up1 1 P16871 99.54 2e-162 X-RAY
 2012-02-08 TYR A:143 A:139 96.0 0.417 S -99.3 -75.4 47.0 0.204 0.213 B:P16871:0.213
 GOL
HOH
 7.373
3.281
 O
CB
 C3
O
TYR B:143 B:139 69.0 0.3 S -77.7 109.6 28.0 0.122 0.178 A:P16871:0.178
 NGA
HOH
 3.191
5.170
 CD2
OH
 O7
O
6p50 1 P16871 99.54 2e-162 X-RAY
 2019-09-04 TYR A:143 NA:NA DO NA DO DO DO NA NA NA
6p67 3 P16871 99.54 2e-162 X-RAY
 2019-09-04 TYR G:143 G:139 83.0 0.361 S -82.2 -69.5 NA NA NA
TYR I:143 I:139 86.0 0.374 S -82.2 -68.4 NA NA NA
TYR J:143 J:139 143.0 0.622 S -81.7 -66.9 NA NA NA
TYR K:143 K:139 129.0 0.561 S -80.8 -68.3 129.0 0.561 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16871-f1 1 P16871 100.0 0.0 TYR A:159 A:159 76.0 0.33 S -103.5 165.7