Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 82499418 . A C CCDS4058.1:NM_003401.3:c.530tAt>tCt_NP_003392.1:p.177Y>S Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7lsy 5 Q13426 99.11 0.0 EM
 2021-04-14 TYR E:177 F:177 131.0 0.57 H -75.3 -33.1 7.0 0.03 0.54 P:P49917:0.361
F:Q13426:0.204
TYR F:177 G:177 142.0 0.617 S -109.1 -66.8 39.0 0.17 0.447 P:P49917:0.174
E:Q13426:0.274
TYR M:177 O:177 141.0 0.613 S -109.2 -66.6 38.0 0.165 0.448 Q:P49917:0.174
N:Q13426:0.278
TYR N:177 P:177 128.0 0.557 H -75.2 -33.2 7.0 0.03 0.527 M:Q13426:0.204
Q:P49917:0.343
7lt3 7 Q13426 99.11 0.0 EM
 2021-04-14 TYR G:177 F:177 132.0 0.574 H -57.8 -43.6 8.0 0.035 0.539 S:P49917:0.478
H:Q13426:0.117
TYR H:177 G:177 145.0 0.63 H -63.7 -43.4 1.0 0.004 0.626 S:P49917:0.483
G:Q13426:0.17
TYR Q:177 O:177 146.0 0.635 H -63.7 -43.4 1.0 0.004 0.631 T:P49917:0.478
R:Q13426:0.183
TYR R:177 P:177 135.0 0.587 H -57.6 -43.6 8.0 0.035 0.552 T:P49917:0.487
Q:Q13426:0.126
7nfc 4 Q13426 99.11 0.0 EM
 2021-08-18 TYR G:177 K:177 157.0 0.683 H -62.6 -41.1 26.0 0.113 0.57 H:Q13426:0.2
I:P49917:0.409
TYR H:177 L:177 134.0 0.583 H -62.6 -40.5 14.0 0.061 0.522 G:Q13426:0.191
I:P49917:0.335
TYR J:177 N:177 125.0 0.543 H -59.1 -49.2 29.0 0.126 0.417 K:Q13426:0.165
L:P49917:0.261
TYR K:177 O:177 138.0 0.6 H -61.7 -43.2 16.0 0.07 0.53 J:Q13426:0.183
L:P49917:0.378
7nfe 5 Q13426 99.11 0.0 EM
 2021-08-18 TYR F:177 H:177 126.0 0.548 H -58.8 -45.1 13.0 0.057 0.491 H:P49917:0.417
G:Q13426:0.126
TYR G:177 I:177 135.0 0.587 H -63.9 -38.4 0.0 0.0 0.587 F:Q13426:0.261
H:P49917:0.43
6abo 1 Q13426 100.0 8e-160 X-RAY
 2019-07-31 TYR A:191 A:177 152.0 0.661 H -73.3 -33.9 125.0 0.543 0.118 B:Q0D2I5:0.117
 HOH
 3.989
 CB
 O
1ik9 1 Q13426 98.12 9e-156 X-RAY
 2001-11-21 TYR A:177 A:177 139.0 0.604 H -50.8 -42.7 8.0 0.035 0.569 C:P49917:0.5
B:Q13426:0.122
 HOH
 2.793
 OH
 O
TYR B:177 B:177 144.0 0.626 H -67.7 -33.7 127.0 0.552 0.074 A:Q13426:0.074
 HOH
 8.451
 CD1
 O
1fu1 1 Q13426 99.51 3e-151 X-RAY
 2000-12-11 TYR A:177 A:177 190.0 0.826 -102.9 70.4 190.0 0.826 0.0
TYR B:177 B:577 143.0 0.622 H -82.1 -47.1 143.0 0.622 0.0
3ii6 1 Q13426 99.01 2e-150 X-RAY
 2009-08-11 TYR A:177 A:177 136.0 0.591 H -36.7 -50.9 11.0 0.048 0.543 E:P49917:0.491
B:Q13426:0.1
 HOH
 3.778
 OH
 O
TYR B:177 B:177 140.0 0.609 H -66.3 -29.7 0.0 0.0 0.609 A:Q13426:0.243
E:P49917:0.452
 HOH
 5.210
 O
 O
TYR C:177 C:177 139.0 0.604 H -38.7 -51.6 NA NA NA
TYR D:177 D:177 140.0 0.609 H -54.1 -40.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13426-f1 1 Q13426 99.11 0.0 TYR A:177 A:177 158.0 0.687 H -61.0 -43.7