Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 88100608 . G A CCDS47244.1:NM_001131005.2:c.65aCa>aTa_NP_001124477.1:p.22T>I Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5f28 1 Q8CFN5 97.8 5e-59 X-RAY
 2016-07-13 THR A:22 A:22 95.0 0.679 H -61.0 -32.0 95.0 0.679 0.0 HOH
 8.536
 O
 O
THR B:22 B:22 66.0 0.471 H -59.7 -36.5 66.0 0.471 0.0
THR C:22 C:22 71.0 0.507 H -62.2 -24.8 NA NA NA
THR D:22 D:22 95.0 0.679 H -61.9 -39.9 NA NA NA
3kov 1 Q02078 96.67 1e-57 X-RAY
 2010-02-16 THR A:21 A:22 71.0 0.507 H -59.9 -45.0 71.0 0.507 0.0 DA
DT
DA
DT
DC
DT
DA
 9.739
7.277
7.818
6.730
9.336
7.690
7.882
 O
O
N
CG2
CG2
O
C
 O3'
OP2
OP2
O5'
OP2
OP2
OP2
THR B:21 B:22 70.0 0.5 H -58.4 -44.9 70.0 0.5 0.0 DA
DT
DA
DT
DC
DA
DT
DA
 9.383
6.944
8.387
7.799
9.173
9.912
7.989
8.455
 O
O
N
CG2
CG2
O
O
C
 O3'
OP2
OP2
O5'
OP2
O3'
OP2
OP2
THR C:21 I:22 70.0 0.5 H -58.8 -43.4 NA NA NA
THR D:21 J:22 68.0 0.486 H -53.9 -44.4 NA NA NA
3p57 1 Q02078 96.67 1e-57 X-RAY
 2011-08-10 THR A:21 A:22 70.0 0.5 H -65.9 -46.9 70.0 0.5 0.0 DA
DT
DA
DT
DT
HOH
 9.860
7.384
8.529
6.936
6.358
3.506
 O
O
N
CG2
CG2
CB
 O3'
OP2
OP2
C3'
OP2
O
THR B:21 B:22 67.0 0.479 H -58.7 -47.9 67.0 0.479 0.0 DA
DA
DT
DA
HOH
 6.847
9.741
7.238
8.571
2.926
 CG2
O
O
N
O
 O5'
O3'
OP2
OP2
O
THR C:21 C:22 67.0 0.479 H -69.0 -41.6 67.0 0.479 0.0 DA
DA
DT
DA
HOH
 7.881
7.471
7.566
8.544
6.778
 CG2
CG2
O
N
O
 O3'
OP2
OP2
OP2
O
THR D:21 D:22 65.0 0.464 H -61.4 -42.6 65.0 0.464 0.0 DA
DT
DA
DT
DC
HOH
 9.658
7.174
8.021
7.315
9.704
3.387
 O
O
N
CG2
CG2
CB
 O3'
OP2
OP2
O5'
OP2
O
THR E:21 I:22 74.0 0.529 H -50.7 -45.6 74.0 0.529 0.0 DA
DA
DA
DT
DA
HOH
 3.830
7.625
9.768
7.271
8.096
2.872
 CG2
CG2
O
O
C
O
 O5'
N7
O3'
OP2
OP2
O
THR F:21 J:22 68.0 0.486 H -58.1 -46.3 68.0 0.486 0.0 DA
DT
DA
DT
DT
HOH
 9.711
7.220
7.668
9.687
7.963
2.731
 O
O
N
OG1
CG2
O
 O3'
OP2
OP2
O5'
OP2
O
6byy 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2018-01-31 THR A:22 A:22 73.0 0.521 H -60.0 -45.3 73.0 0.521 0.0 DA
DA
DT
DA
HOH
 9.396
9.949
7.468
8.442
2.873
 CG2
O
O
N
O
 OP2
O3'
OP2
OP2
O
THR B:22 B:22 85.0 0.607 H -57.4 -44.7 85.0 0.607 0.0 DA
DT
DA
DT
1PG
HOH
 9.893
7.380
8.132
8.971
3.491
2.570
 O
O
N
CG2
OG1
O
 O3'
OP2
OP2
C7
O4
O
THR C:22 C:22 66.0 0.471 H -63.3 -48.2 NA NA NA
THR D:22 D:22 84.0 0.6 H -63.8 -36.1 NA NA NA
6wc2 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2020-07-22 THR A:22 A:22 67.0 0.479 H -61.4 -48.7 67.0 0.479 0.0 DA
DT
DA
DC
HOH
 9.938
7.435
8.423
8.479
4.277
 O
O
N
CG2
OG1
 O3'
OP2
OP2
C6
O
THR B:22 B:22 71.0 0.507 H -60.7 -47.9 71.0 0.507 0.0 DT
DT
DT
DA
DA
HOH
 8.777
8.499
9.711
7.227
7.601
3.688
 OG1
CG2
O
O
N
CB
 OP2
OP2
O3'
OP2
OP2
O
THR C:22 C:22 73.0 0.521 H -60.1 -48.8 NA NA NA
THR D:22 D:22 59.0 0.421 H -62.6 -47.6 NA NA NA
THR I:22 I:22 65.0 0.464 H -61.3 -47.3 NA NA NA
THR J:22 J:22 68.0 0.486 H -59.5 -48.4 NA NA NA
1tqe 3 Q02080 86.02 8e-56 X-RAY
 2004-12-21 THR E:22 P:22 72.0 0.514 H -62.2 -48.1 72.0 0.514 0.0 DA
DT
DA
DT
DT
DG
 9.918
7.544
8.755
6.636
9.457
7.490
 O
O
N
OG1
CG2
CG2
 O3'
OP2
OP2
O5'
O3'
OP2
THR F:22 Q:22 71.0 0.507 H -63.0 -48.7 71.0 0.507 0.0 DA
DA
DA
DA
DT
DA
 6.526
5.389
7.793
9.856
7.391
8.410
 OG1
OG1
CG2
O
O
C
 C3'
OP2
OP2
O3'
OP2
OP2
THR H:22 R:22 72.0 0.514 H -62.3 -48.0 NA NA NA
THR I:22 S:22 71.0 0.507 H -63.1 -48.8 NA NA NA
6c9l 1 Q02080 86.02 8e-56 X-RAY
 2018-02-07 THR A:22 A:22 68.0 0.486 H -60.1 -48.3 68.0 0.486 0.0 HOH
 3.005
 OG1
 O
THR B:22 B:22 77.0 0.55 H -60.4 -46.8 77.0 0.55 0.0 HOH
 2.887
 OG1
 O
THR C:22 C:22 75.0 0.536 H -61.0 -46.0 NA NA NA
THR D:22 D:22 78.0 0.557 H -60.2 -48.0 NA NA NA
THR E:22 E:22 79.0 0.564 H -60.2 -47.7 NA NA NA
THR F:22 F:22 79.0 0.564 H -60.0 -48.1 NA NA NA
6bz1 1 Q02078,Q02080 88.42 9e-56 X-RAY
 2018-02-07 THR A:22 C:22 84.0 0.6 H -63.0 -45.8 84.0 0.6 0.0 DA
DT
DA
DT
 9.724
7.255
8.274
6.037
 O
O
N
CG2
 O3'
OP2
OP2
OP2
THR B:22 D:22 86.0 0.614 H -62.7 -46.1 86.0 0.614 0.0 DA
DA
DT
DA
 7.605
9.677
7.118
8.373
 CG2
O
O
N
 OP1
O3'
OP2
OP2
THR E:22 A:22 83.0 0.593 H -62.9 -45.8 NA NA NA
THR F:22 B:22 76.0 0.543 H -63.3 -45.5 NA NA NA
1n6j 3 Q02080 85.87 6e-55 X-RAY
 2003-11-11 THR C:21 A:22 71.0 0.507 H -59.8 -44.8 71.0 0.507 0.0 DA
DT
DA
HOH
 8.003
7.601
8.506
2.809
 CG2
O
N
OG1
 O5'
OP2
OP2
O
THR D:21 B:22 72.0 0.514 H -60.3 -43.0 72.0 0.514 0.0 DT
DA
DG
DC
HOH
 7.668
8.572
8.040
9.389
2.815
 O
N
CG2
CG2
O
 OP2
OP2
C5'
N4
O
6wc5 1 Q02080 86.67 8e-54 X-RAY
 2020-07-22 THR A:21 A:22 75.0 0.536 H -61.4 -41.8 75.0 0.536 0.0 DA
DT
DA
DT
DC
DA
 9.765
7.346
8.271
9.361
7.843
9.555
 O
O
N
OG1
OG1
OG1
 O3'
OP2
OP2
O4
C5
N6
THR B:21 B:22 63.0 0.45 H -61.3 -41.7 63.0 0.45 0.0 DT
DT
DT
DT
DA
DA
HOH
 8.757
8.738
9.863
9.579
7.160
7.525
7.971
 OG1
OG1
OG1
O
O
N
O
 OP2
OP2
C7
O3'
OP2
OP2
O
THR C:21 C:22 81.0 0.579 H -60.5 -43.3 NA NA NA
THR D:21 D:22 62.0 0.443 H -62.0 -41.8 NA NA NA
1egw 3 Q02078 98.7 9e-50 X-RAY
 2000-03-20 THR E:21 A:22 76.0 0.543 H -62.4 -46.2 76.0 0.543 0.0 DA
DT
DT
DA
DA
DG
DA
DT
DA
HOH
 8.630
9.710
7.187
8.980
8.606
9.606
9.859
7.375
8.631
2.684
 CG2
O
O
N
CG2
CG2
O
O
N
OG1
 OP2
O3'
OP2
OP2
OP2
N7
O3'
OP2
OP2
O
THR F:21 B:22 73.0 0.521 H -60.3 -46.9 73.0 0.521 0.0 DA
DG
DT
DT
DA
DA
DA
DT
DA
HOH
 8.538
9.514
9.811
7.302
8.857
8.532
9.594
7.037
8.133
2.728
 CG2
CG2
O
O
N
CG2
O
O
N
OG1
 OP2
N7
O3'
OP2
OP2
OP2
O3'
OP2
OP2
O
THR G:21 C:22 70.0 0.5 H -57.6 -48.2 NA NA NA
THR H:21 D:22 77.0 0.55 H -60.5 -44.8 NA NA NA
3mu6 1 Q02078 97.18 2e-43 X-RAY
 2011-11-02 THR A:21 A:22 71.0 0.507 H -69.5 -42.2 71.0 0.507 0.0 DT
DT
DA
DA
DG
 9.733
7.232
8.498
8.195
9.908
 O
O
N
CG2
CG2
 O3'
OP2
OP2
OP2
N7
THR B:21 B:22 72.0 0.514 H -69.2 -42.3 72.0 0.514 0.0 DA
DG
DA
DT
DA
 8.143
9.925
9.726
7.251
8.426
 CG2
CG2
O
O
N
 OP2
N7
O3'
OP2
OP2
THR E:21 C:22 73.0 0.521 H -68.9 -41.8 NA NA NA
THR F:21 D:22 72.0 0.514 H -68.0 -42.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q06413-f1 1 Q06413 100.0 0.0 THR A:22 A:22 71.0 0.507 H -54.8 -47.6