Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 142689695 . G A CCDS47298.1:NM_001020825.1:c.1435Cga>Tga_NP_001018661.1:p.479R>* Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7kw7 4 P04150 99.74 0.0 EM
 2021-12-08 ARG F:479 NA:NA DO NA DO DO DO NA NA NA
5emc 2 P04150 97.85 1e-62 X-RAY
 2016-06-29 ARG B:73 A:498 95.0 0.422 H -69.6 -44.3 95.0 0.422 0.0 ZN
HOH
 4.713
2.596
 NH1
NE
 ZN
O
ARG C:73 B:498 72.0 0.32 H -59.5 -42.5 72.0 0.32 0.0 ZN
HOH
 5.815
2.700
 NH2
NH2
 ZN
O
5emp 1 P04150 97.85 1e-62 X-RAY
 2016-06-29 ARG A:73 A:498 71.0 0.316 H -59.3 -46.2 71.0 0.316 0.0 ZN
HOH
 4.664
4.391
 NH2
NH2
 ZN
O
ARG B:73 B:498 80.0 0.356 H -60.8 -46.1 80.0 0.356 0.0 ZN
HOH
 5.749
2.928
 NH1
NH2
 ZN
O
5emq 3 P04150 97.85 1e-62 X-RAY
 2016-06-29 ARG C:73 A:498 100.0 0.444 H -58.6 -44.7 100.0 0.444 0.0 ZN
HOH
 7.101
3.026
 CD
NE
 ZN
O
ARG D:73 B:498 74.0 0.329 H -59.1 -47.6 74.0 0.329 0.0 ZN
HOH
 5.651
2.721
 NH1
NH2
 ZN
O
5e69 1 P04150 96.77 2e-62 X-RAY
 2017-02-08 ARG A:87 A:479 79.0 0.351 H -59.2 -41.6 79.0 0.351 0.0 ZN
HOH
 5.703
2.620
 NH2
NE
 ZN
O
ARG D:87 B:479 57.0 0.253 H -57.3 -43.5 57.0 0.253 0.0 ZN
HOH
 5.774
2.573
 NH2
NH2
 ZN
O
5e6a 1 P04150 96.77 2e-62 X-RAY
 2017-02-08 ARG A:87 A:479 69.0 0.307 H -61.1 -46.4 69.0 0.307 0.0 ZN
HOH
 5.702
2.693
 NH2
NE
 ZN
O
ARG D:87 B:479 57.0 0.253 H -61.6 -42.5 57.0 0.253 0.0 ZN
HOH
 5.601
2.161
 NH2
NH2
 ZN
O
5e6b 1 P04150 96.77 2e-62 X-RAY
 2017-02-08 ARG A:87 A:479 69.0 0.307 H -59.1 -45.2 69.0 0.307 0.0 ZN
HOH
 5.598
2.724
 NH2
NE
 ZN
O
ARG D:87 B:479 57.0 0.253 H -61.5 -40.9 57.0 0.253 0.0 ZN
HOH
 5.619
2.668
 NH2
NE
 ZN
O
5e6c 1 P04150 96.77 2e-62 X-RAY
 2017-02-08 ARG A:87 A:479 88.0 0.391 H -62.2 -43.2 88.0 0.391 0.0 ZN
HOH
 5.825
2.595
 NH2
NH2
 ZN
O
ARG B:87 B:479 70.0 0.311 H -57.7 -39.1 70.0 0.311 0.0 ZN
HOH
 5.951
2.346
 NH2
NH2
 ZN
O
5e6d 3 P04150 96.77 2e-62 X-RAY
 2017-02-08 ARG C:87 A:479 83.0 0.369 H -56.4 -46.8 83.0 0.369 0.0 ZN
HOH
 5.825
2.637
 NH2
NH2
 ZN
O
ARG D:87 B:479 86.0 0.382 H -51.5 -68.1 86.0 0.382 0.0 ZN
HOH
 5.772
2.205
 NH2
NH1
 ZN
O
4hn5 1 P04150 96.77 3e-62 X-RAY
 2012-12-12 ARG A:90 A:479 78.0 0.347 H -56.1 -46.4 78.0 0.347 0.0 ZN
HOH
 5.649
2.931
 NH2
NH2
 ZN
O
ARG D:90 B:479 53.0 0.236 H -54.4 -44.6 53.0 0.236 0.0 ZN
HOH
 5.680
2.708
 NH2
NH1
 ZN
O
5cc1 1 P04150 95.7 4e-62 X-RAY
 2015-12-23 ARG A:87 A:479 72.0 0.32 H -62.6 -42.0 72.0 0.32 0.0 ZN
HOH
 5.570
7.597
 NH2
O
 ZN
O
ARG B:87 B:479 58.0 0.258 H -51.7 -45.5 58.0 0.258 0.0 ZN
HOH
 5.592
3.889
 NH2
N
 ZN
O
ARG E:87 W:479 73.0 0.324 H -62.8 -40.8 NA NA NA
ARG F:87 X:479 57.0 0.253 H -52.2 -45.0 NA NA NA
6cfn 1 P04150 100.0 3e-61 X-RAY
 2018-09-26 ARG A:63 A:479 134.0 0.596 H -60.6 -28.1 134.0 0.596 0.0 ZN
 7.273
 CG
 ZN
ARG B:63 B:479 65.0 0.289 H -59.9 -40.3 NA NA NA
ARG C:63 C:479 131.0 0.582 H -55.9 -43.2 NA NA NA
ARG D:63 D:479 61.0 0.271 H -61.6 -38.7 NA NA NA
ARG E:63 E:479 98.0 0.436 H -72.8 -33.5 NA NA NA
ARG F:63 F:479 111.0 0.493 H -58.2 -38.3 NA NA NA
ARG G:63 G:479 65.0 0.289 H -62.1 -42.9 NA NA NA
ARG H:63 H:479 66.0 0.293 H -52.4 -46.3 NA NA NA
6bse 1 P79269 96.7 6e-60 X-RAY
 2018-12-05 ARG A:65 A:479 66.0 0.293 H -54.2 -43.6 66.0 0.293 0.0 ZN
HOH
 4.613
1.952
 HH21
HH12
 ZN
O
ARG B:65 B:479 77.0 0.342 H -48.4 -45.1 77.0 0.342 0.0 ZN
HOH
 4.435
1.970
 HH21
HE
 ZN
O
6bsf 1 P79269 96.7 6e-60 X-RAY
 2018-12-05 ARG A:65 B:479 114.0 0.507 H -66.8 -45.8 114.0 0.507 0.0 ZN
HOH
 6.222
2.464
 HD2
HE
 ZN
O
ARG D:65 A:479 79.0 0.351 H -61.8 -43.1 79.0 0.351 0.0 ZN
HOH
 4.899
6.501
 HH21
HH21
 ZN
O
3fyl 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 68.0 0.302 H -60.3 -41.1 68.0 0.302 0.0 ZN
EDO
HOH
 5.752
9.288
3.848
 NH2
NE
N
 ZN
C2
O
ARG B:63 B:498 70.0 0.311 H -48.4 -50.0 70.0 0.311 0.0 ZN
HOH
 5.770
2.585
 NH2
NH2
 ZN
O
3g6p 3 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG C:63 A:498 72.0 0.32 H -65.3 -43.0 72.0 0.32 0.0 ZN
ACT
HOH
 5.357
3.542
3.907
 NH2
CD
CA
 ZN
O
O
ARG D:63 B:498 78.0 0.347 H -58.2 -46.7 78.0 0.347 0.0 ZN
HOH
 5.592
2.765
 NH2
NH2
 ZN
O
3g6q 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 B:498 51.0 0.227 H -52.7 -46.3 51.0 0.227 0.0 ZN
HOH
 5.724
3.225
 NH2
NE
 ZN
O
ARG B:63 A:498 76.0 0.338 H -64.7 -43.5 76.0 0.338 0.0 ZN
HOH
 5.839
3.108
 NH2
NE
 ZN
O
3g6r 3 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG C:63 B:498 70.0 0.311 H -52.6 -38.1 70.0 0.311 0.0 ZN
HOH
 5.884
2.771
 NH2
NH2
 ZN
O
ARG D:63 A:498 136.0 0.604 H -67.1 -42.5 136.0 0.604 0.0 ZN
HOH
 7.379
3.208
 NE
NE
 ZN
O
3g6u 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 86.0 0.382 H -57.5 -43.2 86.0 0.382 0.0 ZN
HOH
 6.123
2.626
 NH2
NH2
 ZN
O
ARG B:63 B:498 64.0 0.284 H -53.6 -45.3 64.0 0.284 0.0 ZN
HOH
 5.924
2.554
 NH2
NH2
 ZN
O
3g8u 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 70.0 0.311 H -60.5 -41.4 70.0 0.311 0.0 ZN
HOH
 5.715
2.835
 NH2
NH2
 ZN
O
ARG B:63 B:498 65.0 0.289 H -56.6 -47.8 65.0 0.289 0.0 ZN
HOH
 5.914
2.679
 NH2
NH2
 ZN
O
3g8x 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 72.0 0.32 H -55.9 -45.2 72.0 0.32 0.0 ZN
EDO
HOH
 5.983
9.049
2.792
 NH2
NH2
NH2
 ZN
O1
O
ARG B:63 B:498 62.0 0.276 H -59.4 -45.9 62.0 0.276 0.0 EDO
ZN
HOH
 8.295
6.079
2.535
 NH2
NH2
NH2
 O1
ZN
O
3g97 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 B:498 62.0 0.276 H -62.3 -44.7 62.0 0.276 0.0 ZN
EDO
HOH
 5.813
9.847
3.239
 NH2
NH2
NE
 ZN
O2
O
ARG B:63 A:498 71.0 0.316 H -58.5 -44.3 71.0 0.316 0.0 ZN
EDO
HOH
 5.598
9.210
2.519
 NH2
NH2
NH2
 ZN
C1
O
3g99 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 63.0 0.28 H -67.9 -36.0 63.0 0.28 0.0 ZN
HOH
 5.500
2.733
 NH2
NH2
 ZN
O
ARG B:63 B:498 57.0 0.253 H -52.6 -50.8 57.0 0.253 0.0 ZN
HOH
 5.709
2.808
 NH2
NH2
 ZN
O
3g9i 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 68.0 0.302 H -53.9 -51.2 68.0 0.302 0.0 ZN
EDO
HOH
 5.839
3.840
2.625
 NH2
CB
NH2
 ZN
C2
O
ARG B:63 B:498 66.0 0.293 H -58.6 -44.4 66.0 0.293 0.0 ZN
HOH
 5.712
2.759
 NH2
NH2
 ZN
O
3g9j 3 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG C:63 A:498 70.0 0.311 H -56.4 -44.2 70.0 0.311 0.0 ZN
EDO
HOH
 5.619
8.931
2.884
 NH2
N
NH2
 ZN
O2
O
ARG D:63 B:498 87.0 0.387 H -61.8 -47.0 87.0 0.387 0.0 ZN
EDO
HOH
 6.169
5.718
2.910
 NH2
NH2
NH1
 ZN
O2
O
3g9m 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 A:498 89.0 0.396 H -60.1 -45.0 89.0 0.396 0.0 ZN
EDO
HOH
 5.738
9.391
2.700
 NH2
NH2
NH2
 ZN
O1
O
ARG B:63 B:498 56.0 0.249 H -60.9 -42.4 56.0 0.249 0.0 EDO
ZN
HOH
 9.751
5.757
2.905
 NH2
NH2
NH1
 O2
ZN
O
3g9o 1 P06536 97.7 2e-59 X-RAY
 2009-04-21 ARG A:63 B:498 64.0 0.284 H -55.4 -42.1 64.0 0.284 0.0 ZN
HOH
 5.714
2.833
 NH2
NH1
 ZN
O
ARG B:63 A:498 81.0 0.36 H -61.1 -41.0 81.0 0.36 0.0 ZN
HOH
 5.664
2.301
 NH2
NH2
 ZN
O
3g9p 1 P06536 97.7 2e-59 X-RAY
 2009-04-14 ARG A:63 B:498 64.0 0.284 H -55.4 -42.1 64.0 0.284 0.0 ZN
HOH
 5.714
2.833
 NH2
NH1
 ZN
O
ARG B:63 A:498 81.0 0.36 H -61.1 -41.0 81.0 0.36 0.0 ZN
HOH
 5.664
2.301
 NH2
NH2
 ZN
O
1r4o 2 P06536 95.56 3e-59 X-RAY
 2003-10-21 ARG C:65 A:498 89.0 0.396 H -36.8 -32.3 89.0 0.396 0.0 ZN
HOH
 6.617
2.275
 NH2
NH2
 ZN
O
ARG D:65 B:498 123.0 0.547 H -67.4 -33.1 123.0 0.547 0.0 ZN
HOH
 6.609
3.073
 NH2
CB
 ZN
O
1r4r 3 P06536 95.56 3e-59 X-RAY
 2003-10-28 ARG C:65 A:498 106.0 0.471 H -61.0 -22.0 106.0 0.471 0.0 DT
ZN
 9.626
6.658
 HH21
HE
 OP1
ZN
ARG D:65 B:498 70.0 0.311 H -57.8 -40.1 70.0 0.311 0.0 ZN
 5.671
 HH12
 ZN
4hn6 1 P04150 94.62 3e-59 X-RAY
 2012-12-12 ARG A:87 A:479 69.0 0.307 H -55.7 -42.8 69.0 0.307 0.0 ZN
HOH
 6.213
3.180
 NH2
NE
 ZN
O
ARG D:87 B:479 75.0 0.333 H -61.1 -47.0 75.0 0.333 0.0 ZN
HOH
 5.600
2.716
 NH2
NH2
 ZN
O
3g6t 1 P06536 96.59 1e-57 X-RAY
 2009-04-21 ARG A:64 A:499 66.0 0.293 H -63.4 -38.1 66.0 0.293 0.0 ZN
HOH
 5.793
2.694
 NH2
NH2
 ZN
O
ARG B:64 B:499 65.0 0.289 H -62.0 -40.5 65.0 0.289 0.0 ZN
HOH
 5.624
2.711
 NH2
NH2
 ZN
O
5cby 1 ? 94.05 5e-55 X-RAY
 2015-12-23 ARG A:89 A:479 65.0 0.289 H -55.2 -45.7 65.0 0.289 0.0 ZN
HOH
 5.802
2.572
 NH2
NH2
 ZN
O
ARG B:89 B:479 60.0 0.267 H -54.1 -46.9 60.0 0.267 0.0 ZN
HOH
 5.747
2.603
 NH2
NH2
 ZN
O
5cbx 1 ? 92.86 1e-54 X-RAY
 2015-12-23 ARG A:89 A:479 71.0 0.316 H -58.8 -43.3 71.0 0.316 0.0 ZN
HOH
 5.945
3.946
 NH2
N
 ZN
O
ARG B:89 B:479 57.0 0.253 H -57.9 -46.7 57.0 0.253 0.0 ZN
HOH
 5.653
2.767
 NH2
NE
 ZN
O
ARG E:89 E:479 70.0 0.311 H -62.9 -41.5 NA NA NA
ARG F:89 F:479 59.0 0.262 H -60.0 -44.4 NA NA NA
6x6e 1 P04150 100.0 1e-52 X-RAY
 2021-06-02 ARG A:63 A:479 69.0 0.307 H -60.3 -43.4 69.0 0.307 0.0 ZN
HOH
 5.653
2.767
 NH2
NH2
 ZN
O
ARG B:63 B:479 62.0 0.276 H -56.1 -45.7 62.0 0.276 0.0 ZN
HOH
 5.829
3.989
 NH2
N
 ZN
O
1glu 2 P06536 96.2 3e-52 X-RAY
 1994-01-31 ARG C:65 A:498 68.0 0.302 H -57.7 -54.2 68.0 0.302 0.0 ZN
 6.297
 NE
 ZN
ARG D:65 B:498 114.0 0.507 H -77.3 -23.9 114.0 0.507 0.0 ZN
HOH
 6.627
2.982
 NH1
NH2
 ZN
O
6x6d 1 P04150 100.0 1e-51 X-RAY
 2021-06-02 ARG A:63 A:479 70.0 0.311 H -51.5 -45.3 70.0 0.311 0.0 ZN
HOH
 4.966
9.310
 HH21
HH21
 ZN
O
ARG B:63 B:479 68.0 0.302 H -53.1 -39.1 68.0 0.302 0.0 ZN
HOH
 4.857
2.191
 HH21
HE
 ZN
O
5cbz 1 ? 88.1 5e-50 X-RAY
 2015-12-23 ARG A:89 A:479 77.0 0.342 H -58.4 -40.1 77.0 0.342 0.0 ZN
HOH
 3.972
3.783
 NH2
NH1
 ZN
O
ARG B:89 B:479 60.0 0.267 H -55.3 -49.3 60.0 0.267 0.0 ZN
HOH
 5.594
2.767
 NH2
NH2
 ZN
O
ARG E:89 E:479 60.0 0.267 H -55.0 -46.5 NA NA NA
ARG F:89 F:479 71.0 0.316 H -57.4 -39.8 NA NA NA
5va0 1 P04150 100.0 7e-50 X-RAY
 2017-08-09 ARG A:61 A:479 66.0 0.293 H -54.5 -45.5 66.0 0.293 0.0 ZN
HOH
 5.764
2.980
 NH2
NE
 ZN
O
ARG D:61 B:479 54.0 0.24 H -49.0 -42.9 54.0 0.24 0.0 ZN
HOH
 5.676
2.591
 NH2
NH2
 ZN
O
4oor 1 ? 90.0 9e-50 X-RAY
 2014-10-29 ARG A:65 A:65 68.0 0.302 H -60.2 -44.7 68.0 0.302 0.0 ZN
HOH
 5.787
2.592
 NH2
NH2
 ZN
O
ARG B:65 B:65 65.0 0.289 H -59.5 -45.7 65.0 0.289 0.0 ZN
HOH
 6.018
2.915
 NH2
NH2
 ZN
O
ARG C:65 E:65 117.0 0.52 H -61.3 -44.8 NA NA NA
ARG D:65 F:65 53.0 0.236 H -60.6 -44.1 NA NA NA
4ov7 1 ? 90.0 9e-50 X-RAY
 2014-10-29 ARG A:65 A:65 68.0 0.302 H -60.2 -44.7 68.0 0.302 0.0 ZN
HOH
 5.787
2.592
 NH2
NH2
 ZN
O
ARG B:65 B:65 65.0 0.289 H -59.5 -45.7 65.0 0.289 0.0 ZN
HOH
 6.018
2.915
 NH2
NH2
 ZN
O
ARG C:65 E:65 117.0 0.52 H -61.3 -44.8 NA NA NA
ARG D:65 F:65 53.0 0.236 H -60.6 -44.1 NA NA NA
5cc0 1 ? 85.71 2e-49 X-RAY
 2015-12-23 ARG A:68 A:479 65.0 0.289 H -63.9 -38.6 65.0 0.289 0.0 ZN
HOH
 6.121
8.762
 NH2
N
 ZN
O
ARG D:68 B:479 59.0 0.262 H -56.1 -45.9 59.0 0.262 0.0 ZN
 6.038
 NH2
 ZN
6bqu 1 P04150 98.59 6e-49 X-RAY
 2018-12-05 ARG A:61 B:479 122.0 0.542 H -61.3 -49.6 122.0 0.542 0.0 ZN
HOH
 6.808
2.991
 HD2
HH12
 ZN
O
ARG D:61 A:479 75.0 0.333 H -65.0 -45.3 75.0 0.333 0.0 ZN
HOH
 5.167
9.658
 HH21
HH21
 ZN
O
5va7 1 P04150 100.0 1e-48 X-RAY
 2017-08-09 ARG A:61 A:479 66.0 0.293 H -61.4 -44.7 66.0 0.293 0.0 ZN
HOH
 5.823
2.856
 NH2
NE
 ZN
O
ARG D:61 B:479 58.0 0.258 H -59.5 -46.7 58.0 0.258 0.0 ZN
HOH
 5.814
2.809
 NH2
NH2
 ZN
O
4ond 1 ? 86.25 2e-47 X-RAY
 2014-10-29 ARG A:65 A:65 61.0 0.271 H -54.0 -45.0 61.0 0.271 0.0 ZN
HOH
 5.766
2.707
 NH2
NH2
 ZN
O
ARG B:65 B:65 67.0 0.298 H -54.7 -45.4 67.0 0.298 0.0 ZN
HOH
 5.857
3.554
 NH2
NH1
 ZN
O
ARG C:65 E:65 81.0 0.36 H -57.7 -40.3 NA NA NA
ARG D:65 F:65 63.0 0.28 H -54.6 -47.4 NA NA NA
2c7a 1 P06401 84.62 7e-46 X-RAY
 2006-08-30 ARG A:63 A:625 71.0 0.316 H -50.9 -49.0 71.0 0.316 0.0 ZN
HOH
 5.249
2.854
 NH1
NH2
 ZN
O
ARG B:63 B:625 122.0 0.542 H -59.2 -49.1 122.0 0.542 0.0 ZN
HOH
 6.943
2.566
 NH1
NH2
 ZN
O
1lat 2 P06536 86.25 1e-45 X-RAY
 1996-04-03 ARG C:65 A:498 74.0 0.329 H -58.6 -42.7 74.0 0.329 0.0 ZN
HOH
 4.846
2.828
 NH2
NH1
 ZN
O
ARG D:65 B:498 74.0 0.329 H -60.6 -42.4 74.0 0.329 0.0 ZN
HOH
 6.077
3.448
 NH2
NE
 ZN
O
4tnt 1 P08235 86.42 2e-45 X-RAY
 2014-09-17 GLN A:93 A:661 96.0 0.533 H -65.1 -41.0 96.0 0.533 0.0 ZN
HOH
 7.597
4.262
 OE1
CB
 ZN
O
GLN B:93 B:661 96.0 0.533 H -62.4 -41.4 96.0 0.533 0.0 ZN
HOH
 6.500
8.214
 NE2
NE2
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04150-f1 1 P04150 100.0 0.0 ARG A:479 A:479 75.0 0.333 H -53.0 -44.0