Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158745850 | . | C | A | CCDS4346.1:NM_002187.2:c.749cGg>cTg_NP_002178.2:p.250R>L | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | ARG | B:250 | B:228 | 148.0 | 0.658 | T | 74.5 | 2.9 | 148.0 | 0.658 | 0.0 |
HOH |
5.958 |
N |
O |
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| ARG | D:250 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ARG | B:250 | A:250 | 63.0 | NA | 64.8 | 29.6 | 63.0 | NA | NA | |||||||
| 5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:250 | A:250 | 186.0 | 0.827 | S | -76.3 | 72.0 | 186.0 | 0.827 | 0.0 | ||||||
| 5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:250 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | C:250 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | E:250 | E:250 | 100.0 | NA | 360.0 | -49.6 | NA | NA | NA | ||||||||||||||
| ARG | G:250 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | I:250 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | K:250 | K:250 | 121.0 | NA | 360.0 | 71.3 | NA | NA | NA | ||||||||||||||
| 6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ARG | A:230 | A:250 | 140.0 | 0.622 | T | 55.2 | 38.8 | 140.0 | 0.622 | 0.0 | ||||||
| 3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | ARG | A:230 | A:228 | 140.0 | 0.622 | S | -94.2 | -8.7 | 140.0 | 0.622 | 0.0 | ||||||
| ARG | B:230 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | ARG | A:228 | A:228 | 195.0 | 0.867 | S | -90.9 | -19.4 | 195.0 | 0.867 | 0.0 |
HOH |
4.743 |
N |
O |
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| 1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | ARG | A:228 | A:228 | 184.0 | 0.818 | S | -101.4 | -1.1 | 184.0 | 0.818 | 0.0 | ||||||
| 3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | ARG | A:228 | A:228 | 122.0 | 0.542 | -101.2 | 72.3 | 122.0 | 0.542 | 0.0 | |||||||
| 3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ARG | A:228 | A:228 | 186.0 | 0.827 | -124.2 | 47.4 | 186.0 | 0.827 | 0.0 | |||||||
| 5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:228 | A:250 | 158.0 | 0.702 | S | -90.0 | 2.0 | 158.0 | 0.702 | 0.0 |
NA HOH |
3.759 3.022 |
HA HA |
NA O |
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| 5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:228 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | ARG | B:232 | B:228 | 194.0 | 0.862 | S | -90.3 | -16.9 | 194.0 | 0.862 | 0.0 | ||||||
| 3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | D:228 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | B:228 | B:228 | 68.0 | NA | S | -85.4 | 43.5 | 68.0 | NA | NA | ||||||
| ARG | D:228 | D:228 | 56.0 | NA | S | -100.5 | 43.1 | 56.0 | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | ARG | A:250 | A:250 | 189.0 | 0.84 | S | -79.9 | 0.0 | |