Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 32601136 . G A CCDS3897.1:NM_006713.3:c.330tgG>tgA_NP_006704.3:p.110W>* Homo sapiens SUB1 homolog, transcriptional regulator (SUB1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ycs 1 Q6IBA2 95.77 7e-46 X-RAY
 2020-04-29 TRP A:55 A:110 81.0 0.318 H -61.0 -25.2 7.0 0.027 0.291 B:Q6IBA2:0.29
 OKT
 9.736
 N
 O5'
TRP B:55 B:110 87.0 0.341 H -64.5 -39.4 5.0 0.02 0.321 A:Q6IBA2:0.322
 HOH
 6.206
 CD1
 O
TRP C:55 C:110 89.0 0.349 H -68.1 -35.5 6.0 0.024 0.325 D:Q6IBA2:0.325
 HOH
 9.306
 NE1
 O
TRP D:55 D:110 86.0 0.337 H -64.8 -39.1 6.0 0.024 0.313 C:Q6IBA2:0.314
1pcf 1 P53999 100.0 1e-43 X-RAY
 1998-03-18 TRP A:49 A:110 82.0 0.322 H -62.6 -40.8 4.0 0.016 0.306 B:P53999:0.306
 HOH
 3.571
 CD1
 O
TRP B:49 B:110 88.0 0.345 H -60.2 -39.5 7.0 0.027 0.318 A:P53999:0.318
 HOH
 3.577
 CD1
 O
TRP C:49 C:110 90.0 0.353 H -58.9 -40.9 NA NA NA
TRP D:49 D:110 87.0 0.341 H -58.7 -38.5 NA NA NA
TRP E:49 E:110 87.0 0.341 H -65.0 -34.1 NA NA NA
TRP F:49 F:110 86.0 0.337 H -63.1 -34.5 NA NA NA
TRP G:49 G:110 85.0 0.333 H -60.0 -43.5 NA NA NA
TRP H:49 H:110 85.0 0.333 H -60.9 -38.1 NA NA NA
2c62 1 P53999 100.0 1e-43 X-RAY
 2006-01-11 TRP A:49 A:110 82.0 0.322 H -59.8 -41.4 6.0 0.024 0.298 B:P53999:0.298
 DT
DT
HOH
 9.126
9.542
3.438
 N
N
CD1
 O3'
OP1
O
TRP B:49 B:110 72.0 0.282 H -62.9 -42.3 8.0 0.031 0.251 A:P53999:0.251
 DG
HOH
 8.853
3.859
 N
CD1
 C4'
O
7e4w 1 P53999 100.0 1e-43 X-RAY
 2021-09-22 TRP A:49 A:110 80.0 0.314 H -58.7 -45.7 5.0 0.02 0.294 B:P53999:0.294
 HOH
 7.831
 NE1
 O
TRP B:49 B:110 87.0 0.341 H -60.3 -45.0 6.0 0.024 0.317 A:P53999:0.318
 HOH
 7.889
 N
 O
TRP C:49 C:110 82.0 0.322 H -56.4 -46.6 NA NA NA
TRP D:49 D:110 92.0 0.361 H -57.5 -47.9 NA NA NA
TRP E:49 E:110 80.0 0.314 H -58.8 -47.5 NA NA NA
TRP F:49 F:110 86.0 0.337 H -63.2 -44.1 NA NA NA
TRP G:49 G:110 82.0 0.322 H -59.4 -45.7 NA NA NA
TRP H:49 H:110 83.0 0.325 H -60.3 -46.2 NA NA NA
TRP I:49 I:110 83.0 0.325 H -57.1 -46.7 NA NA NA
TRP J:49 J:110 84.0 0.329 H -59.1 -45.4 NA NA NA
TRP K:49 K:110 85.0 0.333 H -61.9 -44.0 NA NA NA
TRP L:49 L:110 82.0 0.322 H -58.4 -45.8 NA NA NA
TRP M:49 M:110 82.0 0.322 H -59.3 -46.5 NA NA NA
TRP N:49 N:110 87.0 0.341 H -58.9 -46.3 NA NA NA
TRP O:49 O:110 84.0 0.329 H -57.2 -46.8 NA NA NA
TRP P:49 P:110 77.0 0.302 H -59.6 -44.6 NA NA NA
4usg 1 P53999 98.46 1e-42 X-RAY
 2015-03-18 TRP A:49 A:110 78.0 0.306 H -63.7 -41.0 4.0 0.016 0.29 B:P53999:0.29
 DT
DT
HOH
 9.384
9.282
3.562
 N
N
CD1
 O3'
O3'
O
TRP B:49 B:110 76.0 0.298 H -65.5 -40.0 5.0 0.02 0.278 A:P53999:0.278
 DT
DT
DT
HOH
 8.960
9.545
7.511
3.503
 N
N
N
CD1
 O4'
OP1
OP1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p53999-f1 1 P53999 100.0 2e-87 TRP A:110 A:110 83.0 0.325 H -64.2 -38.6