Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 88100479 . A C CCDS47244.1:NM_001131005.2:c.194gTg>gGg_NP_001124477.1:p.65V>G Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5f28 1 Q8CFN5 97.8 5e-59 X-RAY
 2016-07-13 VAL A:65 A:65 19.0 0.123 H -65.4 -45.9 0.0 0.0 0.123 B:Q8CFN5:0.123
 HOH
 8.145
 N
 O
VAL B:65 B:65 19.0 0.123 H -65.1 -39.5 0.0 0.0 0.123 A:Q8CFN5:0.123
 HOH
 8.370
 CA
 O
VAL C:65 C:65 26.0 0.168 H -66.7 -43.4 NA NA NA
VAL D:65 D:65 23.0 0.148 H -71.8 -36.9 NA NA NA
3kov 1 Q02078 96.67 1e-57 X-RAY
 2010-02-16 VAL A:64 A:65 22.0 0.142 H -69.8 -48.4 0.0 0.0 0.142 B:Q02078:0.142
VAL B:64 B:65 21.0 0.135 H -68.9 -47.7 0.0 0.0 0.135 A:Q02078:0.135
VAL C:64 I:65 23.0 0.148 H -67.9 -48.5 NA NA NA
VAL D:64 J:65 23.0 0.148 H -71.3 -46.6 NA NA NA
3p57 1 Q02078 96.67 1e-57 X-RAY
 2011-08-10 VAL A:64 A:65 24.0 0.155 H -59.8 -40.5 0.0 0.0 0.155 B:Q02078:0.155
 HOH
 7.311
 O
 O
VAL B:64 B:65 22.0 0.142 H -69.2 -41.6 1.0 0.006 0.136 A:Q02078:0.135
 HOH
 6.445
 O
 O
VAL C:64 C:65 21.0 0.135 H -64.3 -37.4 0.0 0.0 0.135 D:Q02078:0.135
 HOH
 7.026
 CG2
 O
VAL D:64 D:65 23.0 0.148 H -67.0 -38.6 0.0 0.0 0.148 C:Q02078:0.148
 HOH
 4.947
 N
 O
VAL E:64 I:65 24.0 0.155 H -68.8 -45.6 1.0 0.006 0.149 F:Q02078:0.148
 HOH
 6.011
 C
 O
VAL F:64 J:65 24.0 0.155 H -68.3 -47.8 0.0 0.0 0.155 E:Q02078:0.155
 HOH
 3.476
 CG2
 O
6byy 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2018-01-31 VAL A:65 A:65 33.0 0.213 H -66.2 -46.7 8.0 0.052 0.161 B:Q02078+Q02080:0.161
 1PG
HOH
 3.676
3.361
 CG2
CG2
 C1
O
VAL B:65 B:65 24.0 0.155 H -66.2 -40.8 0.0 0.0 0.155 A:Q02078+Q02080:0.155
 HOH
 3.710
 CG2
 O
VAL C:65 C:65 32.0 0.206 H -67.4 -46.0 NA NA NA
VAL D:65 D:65 22.0 0.142 H -71.4 -36.6 NA NA NA
6wc2 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2020-07-22 VAL A:65 A:65 23.0 0.148 H -67.3 -43.8 0.0 0.0 0.148 B:Q02078+Q02080:0.148
 HOH
 3.256
 CG2
 O
VAL B:65 B:65 25.0 0.161 H -63.8 -45.0 0.0 0.0 0.161 A:Q02078+Q02080:0.161
 HOH
 5.976
 C
 O
VAL C:65 C:65 26.0 0.168 H -66.2 -44.0 NA NA NA
VAL D:65 D:65 19.0 0.123 H -68.5 -43.4 NA NA NA
VAL I:65 I:65 24.0 0.155 H -65.1 -43.5 NA NA NA
VAL J:65 J:65 24.0 0.155 H -65.1 -43.6 NA NA NA
1tqe 3 Q02080 86.02 8e-56 X-RAY
 2004-12-21 VAL E:65 P:65 23.0 0.148 H -54.1 -60.3 0.0 0.0 0.148 F:Q02080:0.148
VAL F:65 Q:65 25.0 0.161 H -53.8 -44.1 0.0 0.0 0.161 E:Q02080:0.161
VAL H:65 R:65 25.0 0.161 H -60.6 -58.6 NA NA NA
VAL I:65 S:65 23.0 0.148 H -64.8 -56.9 NA NA NA
6c9l 1 Q02080 86.02 8e-56 X-RAY
 2018-02-07 VAL A:65 A:65 20.0 0.129 H -67.1 -43.0 0.0 0.0 0.129 B:Q02080:0.129
 HOH
 6.451
 CG2
 O
VAL B:65 B:65 21.0 0.135 H -67.2 -42.8 0.0 0.0 0.135 A:Q02080:0.135
 HOH
 4.944
 N
 O
VAL C:65 C:65 21.0 0.135 H -67.2 -42.7 NA NA NA
VAL D:65 D:65 19.0 0.123 H -67.6 -43.3 NA NA NA
VAL E:65 E:65 21.0 0.135 H -67.4 -42.8 NA NA NA
VAL F:65 F:65 21.0 0.135 H -67.4 -42.7 NA NA NA
6bz1 1 Q02078,Q02080 88.42 9e-56 X-RAY
 2018-02-07 VAL A:65 C:65 20.0 0.129 H -65.2 -44.5 0.0 0.0 0.129 B:Q02078+Q02080:0.129
VAL B:65 D:65 19.0 0.123 H -65.1 -44.4 0.0 0.0 0.123 A:Q02078+Q02080:0.123
VAL E:65 A:65 19.0 0.123 H -65.2 -44.5 NA NA NA
VAL F:65 B:65 19.0 0.123 H -66.0 -43.7 NA NA NA
1n6j 3 Q02080 85.87 6e-55 X-RAY
 2003-11-11 VAL C:64 A:65 20.0 0.129 H -63.6 -45.4 0.0 0.0 0.129 D:Q02080:0.129
 HOH
 5.530
 N
 O
VAL D:64 B:65 21.0 0.135 H -63.0 -46.0 0.0 0.0 0.135 C:Q02080:0.135
 HOH
 5.034
 N
 O
6wc5 1 Q02080 86.67 8e-54 X-RAY
 2020-07-22 VAL A:64 A:65 22.0 0.142 H -65.5 -47.9 1.0 0.006 0.136 B:Q02080:0.135
VAL B:64 B:65 21.0 0.135 H -65.3 -48.4 0.0 0.0 0.135 A:Q02080:0.135
VAL C:64 C:65 24.0 0.155 H -66.3 -47.2 NA NA NA
VAL D:64 D:65 22.0 0.142 H -65.7 -48.1 NA NA NA
1egw 3 Q02078 98.7 9e-50 X-RAY
 2000-03-20 VAL E:64 A:65 20.0 0.129 H -65.4 -46.2 0.0 0.0 0.129 F:Q02078:0.129
 HOH
 6.046
 C
 O
VAL F:64 B:65 18.0 0.116 H -59.0 -42.1 0.0 0.0 0.116 E:Q02078:0.116
 HOH
 7.010
 N
 O
VAL G:64 C:65 19.0 0.123 H -60.4 -41.9 NA NA NA
VAL H:64 D:65 18.0 0.116 H -68.4 -46.4 NA NA NA
3mu6 1 Q02078 97.18 2e-43 X-RAY
 2011-11-02 VAL A:64 A:65 21.0 0.135 H -56.1 -43.7 0.0 0.0 0.135 B:Q02078:0.135
 BXL
 6.490
 C
 C8
VAL B:64 B:65 20.0 0.129 H -58.5 -44.4 0.0 0.0 0.129 A:Q02078:0.129
 BXL
 6.593
 C
 C2
VAL E:64 C:65 21.0 0.135 H -56.9 -46.7 NA NA NA
VAL F:64 D:65 20.0 0.129 H -57.6 -45.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q06413-f1 1 Q06413 100.0 0.0 VAL A:65 A:65 19.0 0.123 H -70.4 -33.9