Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 88100584 . T A CCDS47244.1:NM_001131005.2:c.89aAg>aTg_NP_001124477.1:p.30K>M Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5f28 1 Q8CFN5 97.8 5e-59 X-RAY
 2016-07-13 LYS A:30 A:30 96.0 0.48 H -58.1 -37.6 67.0 0.335 0.145 B:Q8CFN5:0.145
 HOH
 7.990
 CD
 O
LYS B:30 B:30 112.0 0.56 H -66.3 -46.8 82.0 0.41 0.15 A:Q8CFN5:0.15
 HOH
 7.483
 CG
 O
LYS C:30 C:30 108.0 0.54 H -60.8 -42.5 NA NA NA
LYS D:30 D:30 105.0 0.525 H -66.2 -46.9 NA NA NA
3kov 1 Q02078 96.67 1e-57 X-RAY
 2010-02-16 LYS A:29 A:30 106.0 0.53 H -57.8 -58.7 80.0 0.4 0.13 B:Q02078:0.13
 DT
DT
DA
DT
DA
DA
DA
DT
 8.680
5.126
3.971
8.111
8.531
4.277
2.226
7.032
 NZ
NZ
NZ
O
NZ
NZ
NZ
CD
 O3'
O3'
OP2
OP1
O3'
O3'
OP2
OP2
LYS B:29 B:30 106.0 0.53 H -60.9 -52.8 77.0 0.385 0.145 A:Q02078:0.145
 DT
DT
DA
DT
DA
DA
DA
DT
 8.723
5.116
3.591
8.307
9.174
4.514
2.334
6.144
 NZ
NZ
NZ
CB
NZ
NZ
NZ
NZ
 O3'
O3'
OP2
OP2
O3'
O3'
OP2
C7
LYS C:29 I:30 107.0 0.535 H -60.9 -52.6 NA NA NA
LYS D:29 J:30 109.0 0.545 H -62.5 -47.9 NA NA NA
3p57 1 Q02078 96.67 1e-57 X-RAY
 2011-08-10 LYS A:29 A:30 109.0 0.545 H -64.8 -48.5 76.0 0.38 0.165 B:Q02078:0.165
 DT
DT
DA
DT
DA
DT
HOH
 9.162
4.704
2.756
7.363
9.843
8.236
3.130
 NZ
NZ
NZ
CB
C
C
NZ
 O3'
O3'
OP2
OP2
O3'
OP1
O
LYS B:29 B:30 112.0 0.56 H -61.1 -49.8 77.0 0.385 0.175 A:Q02078:0.175
 DA
DT
DA
DA
DA
DT
HOH
 9.934
8.434
9.025
4.890
2.962
7.161
2.669
 C
C
NZ
NZ
NZ
CB
NZ
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS C:29 C:30 111.0 0.555 H -55.0 -55.2 82.0 0.41 0.145 D:Q02078:0.145
 DA
DT
DA
DA
DA
DT
HOH
 9.871
8.336
8.906
4.454
2.539
7.208
3.716
 C
C
NZ
NZ
NZ
CB
CD
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS D:29 D:30 112.0 0.56 H -62.5 -46.9 73.0 0.365 0.195 C:Q02078:0.195
 DT
DT
DA
DT
DA
DT
HOH
 8.859
4.684
2.806
7.223
9.770
8.234
3.713
 NZ
NZ
NZ
CB
C
C
CD
 O3'
O3'
OP2
OP2
O3'
OP1
O
LYS E:29 I:30 111.0 0.555 H -70.5 -42.6 80.0 0.4 0.155 F:Q02078:0.155
 DA
DT
DA
DA
DA
DT
HOH
 9.809
8.211
8.796
4.590
2.771
7.258
3.967
 C
O
NZ
CE
NZ
CB
CD
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS F:29 J:30 108.0 0.54 H -59.0 -47.1 77.0 0.385 0.155 E:Q02078:0.155
 DT
DT
DA
DT
DA
DT
HOH
 8.953
4.707
2.648
7.129
9.861
8.340
3.779
 NZ
NZ
NZ
CB
C
C
CB
 O3'
O3'
OP2
OP2
O3'
OP1
O
6byy 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2018-01-31 LYS A:30 A:30 101.0 0.505 H -61.5 -45.7 46.0 0.23 0.275 B:Q02078+Q02080:0.275
 DA
DT
DA
DA
DA
DT
HOH
 9.746
8.282
8.260
4.076
3.057
7.295
2.887
 C
O
NZ
NZ
NZ
CB
NZ
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS B:30 B:30 106.0 0.53 H -65.0 -43.7 77.0 0.385 0.145 A:Q02078+Q02080:0.145
 DT
DT
DA
DT
DA
DT
HOH
 8.893
4.627
2.965
7.217
9.860
8.306
2.895
 NZ
CE
NZ
CB
C
C
NZ
 O3'
O3'
OP2
OP2
O3'
OP1
O
LYS C:30 C:30 103.0 0.515 H -44.0 -57.3 NA NA NA
LYS D:30 D:30 98.0 0.49 H -47.9 -59.6 NA NA NA
6wc2 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2020-07-22 LYS A:30 A:30 105.0 0.525 H -64.8 -42.0 70.0 0.35 0.175 B:Q02078+Q02080:0.175
 DA
DA
DA
DT
DT
DA
HOH
 9.172
4.862
2.976
7.260
9.930
8.248
3.062
 NZ
NZ
NZ
CB
C
C
NZ
 O3'
O3'
OP2
OP2
O3'
OP1
O
LYS B:30 B:30 105.0 0.525 H -63.9 -44.2 73.0 0.365 0.16 A:Q02078+Q02080:0.16
 DA
DT
DT
DT
DT
DA
HOH
 9.872
8.324
8.726
4.394
2.748
7.089
3.856
 C
C
NZ
NZ
NZ
CB
NZ
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS C:30 C:30 104.0 0.52 H -65.8 -42.8 NA NA NA
LYS D:30 D:30 105.0 0.525 H -66.2 -42.9 NA NA NA
LYS I:30 I:30 104.0 0.52 H -65.2 -43.9 NA NA NA
LYS J:30 J:30 106.0 0.53 H -64.1 -44.5 NA NA NA
1tqe 3 Q02080 86.02 8e-56 X-RAY
 2004-12-21 LYS E:30 P:30 108.0 0.54 H -60.7 -52.8 81.0 0.405 0.135 F:Q02080:0.135
 DT
DT
DA
DT
DA
DT
 8.723
4.236
2.526
7.146
9.836
8.201
 NZ
NZ
NZ
CD
C
C
 O3'
O3'
OP2
OP2
O3'
OP1
LYS F:30 Q:30 111.0 0.555 H -61.1 -54.4 80.0 0.4 0.155 E:Q02080:0.155
 DA
DT
DA
DA
DA
DT
 9.923
8.453
8.944
4.453
2.566
6.967
 C
C
NZ
NZ
NZ
NZ
 O3'
OP1
O3'
O3'
OP2
C7
LYS H:30 R:30 109.0 0.545 H -60.8 -52.3 NA NA NA
LYS I:30 S:30 109.0 0.545 H -60.3 -55.1 NA NA NA
6c9l 1 Q02080 86.02 8e-56 X-RAY
 2018-02-07 LYS A:30 A:30 106.0 0.53 H -60.2 -46.3 78.0 0.39 0.14 B:Q02080:0.14
 HOH
 5.697
 O
 O
LYS B:30 B:30 93.0 0.465 H -60.5 -45.7 66.0 0.33 0.135 A:Q02080:0.135
 HOH
 5.415
 O
 O
LYS C:30 C:30 93.0 0.465 H -60.3 -45.6 NA NA NA
LYS D:30 D:30 94.0 0.47 H -60.7 -45.6 NA NA NA
LYS E:30 E:30 104.0 0.52 H -60.0 -45.3 NA NA NA
LYS F:30 F:30 100.0 0.5 H -60.4 -45.2 NA NA NA
6bz1 1 Q02078,Q02080 88.42 9e-56 X-RAY
 2018-02-07 LYS A:30 C:30 102.0 0.51 H -59.0 -49.1 102.0 0.51 0.0 DT
DT
DA
DT
DT
 9.298
4.888
3.039
7.315
8.342
 NZ
NZ
NZ
CB
C
 O3'
O3'
OP2
OP2
OP1
LYS B:30 D:30 103.0 0.515 H -58.6 -49.2 102.0 0.51 0.005 A:Q02078+Q02080:0.005
 DA
DT
DA
DA
DA
DT
 9.726
8.358
9.274
5.028
3.048
7.412
 C
C
NZ
NZ
NZ
CB
 O3'
OP1
O3'
O3'
OP2
OP2
LYS E:30 A:30 99.0 0.495 H -58.8 -49.3 NA NA NA
LYS F:30 B:30 101.0 0.505 H -59.1 -49.4 NA NA NA
1n6j 3 Q02080 85.87 6e-55 X-RAY
 2003-11-11 LYS C:29 A:30 105.0 0.525 H -56.0 -46.2 73.0 0.365 0.16 D:Q02080:0.16
 DA
DT
DA
DA
DA
DT
HOH
 9.840
8.136
8.668
4.450
2.913
7.434
2.994
 C
C
NZ
NZ
NZ
CB
NZ
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS D:29 B:30 105.0 0.525 H -56.4 -45.7 75.0 0.375 0.15 C:Q02080:0.15
 DT
DT
DA
DT
DA
DT
HOH
 8.483
4.386
2.845
7.246
9.905
8.541
3.038
 NZ
NZ
NZ
CB
C
C
NZ
 O3'
O3'
OP2
OP2
O3'
OP1
O
6wc5 1 Q02080 86.67 8e-54 X-RAY
 2020-07-22 LYS A:29 A:30 96.0 0.48 H -60.8 -49.1 62.0 0.31 0.17 B:Q02080:0.17
 DA
DA
DA
DT
DA
HOH
 9.357
4.700
3.236
7.244
8.390
7.025
 NZ
CE
CE
CB
C
C
 O3'
O3'
OP1
OP2
OP1
O
LYS B:29 B:30 108.0 0.54 H -61.2 -48.8 78.0 0.39 0.15 A:Q02080:0.15
 DA
DT
DT
DT
DT
DA
HOH
 9.807
8.410
8.926
4.662
2.680
6.934
8.090
 C
C
NZ
NZ
NZ
CB
N
 O3'
OP1
O3'
O3'
OP2
OP2
O
LYS C:29 C:30 109.0 0.545 H -60.9 -48.5 NA NA NA
LYS D:29 D:30 109.0 0.545 H -61.1 -48.4 NA NA NA
1egw 3 Q02078 98.7 9e-50 X-RAY
 2000-03-20 LYS E:29 A:30 114.0 0.57 H -63.9 -45.4 114.0 0.57 0.0 HOH
 6.691
 N
 O
LYS F:29 B:30 105.0 0.525 H -64.3 -45.5 105.0 0.525 0.0 HOH
 6.740
 N
 O
LYS G:29 C:30 113.0 0.565 H -63.2 -48.6 NA NA NA
LYS H:29 D:30 113.0 0.565 H -62.3 -47.4 NA NA NA
3mu6 1 Q02078 97.18 2e-43 X-RAY
 2011-11-02 LYS A:29 A:30 114.0 0.57 H -57.3 -49.3 114.0 0.57 0.0 DT
DA
DT
DT
DA
DT
 8.679
4.309
2.449
7.345
9.939
8.256
 NZ
NZ
NZ
CB
C
C
 O3'
O3'
OP2
OP2
O3'
OP1
LYS B:29 B:30 115.0 0.575 H -58.0 -48.3 115.0 0.575 0.0 DT
DT
DT
DA
DA
DT
 9.900
8.368
8.675
4.368
2.460
7.239
 C
C
NZ
NZ
NZ
CB
 O3'
OP1
O3'
O3'
OP2
OP2
LYS E:29 C:30 114.0 0.57 H -58.2 -48.0 NA NA NA
LYS F:29 D:30 116.0 0.58 H -58.0 -48.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q06413-f1 1 Q06413 100.0 0.0 LYS A:30 A:30 111.0 0.555 H -62.4 -38.2