Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 88100593 . C A CCDS47244.1:NM_001131005.2:c.80gGg>gTg_NP_001124477.1:p.27G>V Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5f28 1 Q8CFN5 97.8 5e-59 X-RAY
 2016-07-13 GLY A:27 A:27 35.0 0.467 H -62.8 -36.2 21.0 0.28 0.187 B:Q8CFN5:0.187
 HOH
 4.561
 CA
 O
GLY B:27 B:27 37.0 0.493 H -62.1 -29.9 33.0 0.44 0.053 A:Q8CFN5:0.053
 HOH
 8.862
 O
 O
GLY C:27 C:27 31.0 0.413 H -61.7 -31.5 NA NA NA
GLY D:27 D:27 33.0 0.44 H -58.4 -33.3 NA NA NA
3kov 1 Q02078 96.67 1e-57 X-RAY
 2010-02-16 GLY A:26 A:27 33.0 0.44 H -56.4 -48.7 33.0 0.44 0.0 DT
DA
DT
DA
DA
DT
DA
 7.734
5.366
4.558
7.986
4.784
3.697
9.066
 CA
O
CA
O
CA
CA
N
 O3'
OP1
OP2
O3'
O3'
OP2
OP2
GLY B:26 B:27 32.0 0.427 H -58.3 -49.5 32.0 0.427 0.0 DT
DA
DT
DA
DA
DT
DA
 7.946
5.163
4.304
8.126
4.307
4.278
9.031
 CA
CA
CA
O
CA
CA
CA
 O3'
C3'
OP2
O3'
C3'
OP1
OP2
GLY C:26 I:27 30.0 0.4 H -57.4 -49.4 NA NA NA
GLY D:26 J:27 30.0 0.4 H -59.1 -46.2 NA NA NA
3p57 1 Q02078 96.67 1e-57 X-RAY
 2011-08-10 GLY A:26 A:27 34.0 0.453 H -60.9 -39.8 34.0 0.453 0.0 DT
DA
DT
DA
DA
DT
HOH
 7.549
5.235
3.643
9.961
8.836
8.118
2.993
 O
O
CA
N
O
O
O
 O3'
OP1
OP2
OP2
O3'
OP1
O
GLY B:26 B:27 33.0 0.44 H -55.4 -38.9 32.0 0.427 0.013 A:Q02078:0.013
 DA
DT
DA
DA
DT
HOH
 8.824
8.183
7.379
4.995
3.501
2.964
 O
O
O
CA
CA
O
 O3'
OP1
O3'
C3'
OP2
O
GLY C:26 C:27 34.0 0.453 H -56.2 -38.5 31.0 0.413 0.04 D:Q02078:0.04
 DA
DT
DA
DA
DT
DA
HOH
 8.778
8.143
7.555
5.212
3.552
9.959
3.049
 O
O
O
CA
CA
N
O
 O3'
OP1
O3'
C3'
OP2
OP2
O
GLY D:26 D:27 31.0 0.413 H -66.3 -35.8 31.0 0.413 0.0 DT
DA
DT
DA
DA
DT
HOH
 7.495
5.079
3.384
9.774
8.738
8.112
2.945
 O
CA
CA
N
O
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
O
GLY E:26 I:27 35.0 0.467 H -52.7 -40.7 35.0 0.467 0.0 DA
DA
DT
DA
DA
DT
DA
HOH
 8.954
8.752
8.052
7.441
5.003
3.340
9.796
3.047
 N
O
O
O
CA
CA
N
O
 O5'
O3'
OP1
O3'
O3'
OP2
OP2
O
GLY F:26 J:27 30.0 0.4 H -60.5 -40.7 29.0 0.387 0.013 E:Q02078:0.013
 DT
DA
DT
DA
DA
DT
HOH
 7.574
4.899
3.360
9.647
8.777
8.070
3.094
 O
CA
CA
N
O
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
O
6byy 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2018-01-31 GLY A:27 A:27 33.0 0.44 H -56.8 -38.7 28.0 0.373 0.067 B:Q02078+Q02080:0.067
 DA
DT
DA
DA
DT
DA
HOH
 8.771
8.199
7.424
5.138
3.576
9.861
2.950
 O
O
O
CA
CA
N
O
 O3'
OP1
O3'
C3'
OP2
OP2
O
GLY B:27 B:27 31.0 0.413 H -63.3 -35.5 26.0 0.347 0.066 A:Q02078+Q02080:0.067
 DT
DA
DT
DA
DA
DT
HOH
 7.403
5.152
3.476
9.750
8.830
8.083
2.999
 O
CA
CA
N
O
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
O
GLY C:27 C:27 32.0 0.427 H -62.2 -37.2 NA NA NA
GLY D:27 D:27 35.0 0.467 H -59.0 -41.6 NA NA NA
6wc2 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2020-07-22 GLY A:27 A:27 36.0 0.48 H -56.8 -39.5 31.0 0.413 0.067 B:Q02078+Q02080:0.067
 DA
DA
DT
DA
DT
DA
HOH
 7.522
5.172
3.468
9.846
8.951
8.019
2.816
 O
CA
CA
CA
O
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
O
GLY B:27 B:27 35.0 0.467 H -57.9 -39.6 30.0 0.4 0.067 A:Q02078+Q02080:0.067
 DA
DT
DT
DT
DA
HOH
 8.726
8.064
7.440
5.171
3.306
2.799
 O
O
O
O
CA
O
 O3'
OP1
O3'
OP1
OP2
O
GLY C:27 C:27 33.0 0.44 H -61.5 -36.6 NA NA NA
GLY D:27 D:27 35.0 0.467 H -58.4 -38.8 NA NA NA
GLY I:27 I:27 34.0 0.453 H -58.1 -37.2 NA NA NA
GLY J:27 J:27 35.0 0.467 H -58.3 -39.6 NA NA NA
1tqe 3 Q02080 86.02 8e-56 X-RAY
 2004-12-21 GLY E:27 P:27 30.0 0.4 H -54.5 -42.2 26.0 0.347 0.053 F:Q02080:0.053
 DT
DA
DT
DA
DA
DT
 7.792
5.269
4.111
9.762
9.019
8.051
 O
CA
CA
CA
O
O
 O3'
C3'
OP2
OP1
O3'
OP1
GLY F:27 Q:27 29.0 0.387 H -54.0 -40.9 25.0 0.333 0.054 E:Q02080:0.053
 DA
DT
DA
DA
DT
DA
 9.070
8.292
7.935
5.243
3.899
9.875
 O
O
O
CA
CA
N
 O3'
OP1
O3'
C3'
OP2
OP2
GLY H:27 R:27 29.0 0.387 H -54.3 -42.7 NA NA NA
GLY I:27 S:27 30.0 0.4 H -54.0 -41.5 NA NA NA
6c9l 1 Q02080 86.02 8e-56 X-RAY
 2018-02-07 GLY A:27 A:27 30.0 0.4 H -53.4 -44.7 30.0 0.4 0.0 HOH
 3.908
 CA
 O
GLY B:27 B:27 29.0 0.387 H -53.0 -45.3 29.0 0.387 0.0 HOH
 3.678
 N
 O
GLY C:27 C:27 30.0 0.4 H -52.4 -45.6 NA NA NA
GLY D:27 D:27 29.0 0.387 H -54.0 -44.1 NA NA NA
GLY E:27 E:27 32.0 0.427 H -53.7 -44.1 NA NA NA
GLY F:27 F:27 30.0 0.4 H -53.5 -43.9 NA NA NA
6bz1 1 Q02078,Q02080 88.42 9e-56 X-RAY
 2018-02-07 GLY A:27 C:27 29.0 0.387 H -61.6 -34.4 26.0 0.347 0.04 B:Q02078+Q02080:0.04
 DT
DA
DT
DA
DA
DT
 7.387
4.963
3.587
9.778
8.994
8.011
 O
CA
CA
N
O
O
 O3'
O3'
OP2
OP2
O3'
OP1
GLY B:27 D:27 30.0 0.4 H -61.5 -34.8 27.0 0.36 0.04 A:Q02078+Q02080:0.04
 DA
DT
DA
DA
DT
DA
 8.599
8.165
7.387
4.929
3.689
9.896
 O
O
O
CA
CA
N
 O3'
OP1
O3'
C3'
OP2
OP2
GLY E:27 A:27 31.0 0.413 H -61.4 -34.9 NA NA NA
GLY F:27 B:27 32.0 0.427 H -60.0 -35.7 NA NA NA
1n6j 3 Q02080 85.87 6e-55 X-RAY
 2003-11-11 GLY C:26 A:27 32.0 0.427 H -57.6 -37.4 29.0 0.387 0.04 D:Q02080:0.04
 DA
DT
DA
DA
DT
HOH
 8.709
7.730
7.611
5.256
3.756
2.866
 O
O
O
CA
CA
O
 O3'
OP1
O3'
C3'
OP2
O
GLY D:26 B:27 33.0 0.44 H -56.6 -39.4 28.0 0.373 0.067 C:Q02080:0.067
 DT
DA
DT
DA
DA
DT
HOH
 7.587
5.209
3.505
9.970
8.771
8.266
2.890
 O
CA
CA
CA
O
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
O
6wc5 1 Q02080 86.67 8e-54 X-RAY
 2020-07-22 GLY A:26 A:27 33.0 0.44 H -52.2 -44.6 33.0 0.44 0.0 DA
DA
DT
DA
DT
DA
HOH
 7.346
5.036
3.558
9.866
8.967
8.003
7.221
 O
O
CA
N
O
O
O
 O3'
OP1
OP2
OP2
O3'
OP1
O
GLY B:26 B:27 31.0 0.413 H -53.0 -44.4 26.0 0.347 0.066 A:Q02080:0.067
 DA
DT
DT
DT
DA
DA
HOH
 8.733
8.143
7.370
4.917
3.190
9.901
4.485
 O
O
O
CA
CA
CA
C
 O3'
OP1
O3'
C3'
OP2
OP1
O
GLY C:26 C:27 34.0 0.453 H -51.2 -44.6 NA NA NA
GLY D:26 D:27 31.0 0.413 H -52.1 -44.1 NA NA NA
1egw 3 Q02078 98.7 9e-50 X-RAY
 2000-03-20 GLY E:26 A:27 32.0 0.427 H -62.5 -35.2 26.0 0.347 0.08 F:Q02078:0.08
 DA
DT
DT
DA
DA
DT
DA
HOH
 7.435
5.098
3.565
7.426
5.080
3.671
9.899
2.913
 O
CA
CA
O
O
CA
N
O
 O3'
C3'
OP2
O3'
OP1
OP2
OP2
O
GLY F:26 B:27 32.0 0.427 H -62.3 -39.7 27.0 0.36 0.067 E:Q02078:0.067
 DA
DT
DT
DA
DA
DT
DA
HOH
 7.498
5.162
3.679
7.452
5.035
3.427
9.930
2.964
 O
O
CA
O
CA
CA
N
O
 O3'
OP1
OP2
O3'
C3'
OP2
OP2
O
GLY G:26 C:27 30.0 0.4 H -61.4 -39.0 NA NA NA
GLY H:26 D:27 30.0 0.4 H -61.7 -36.2 NA NA NA
3mu6 1 Q02078 97.18 2e-43 X-RAY
 2011-11-02 GLY A:26 A:27 34.0 0.453 H -53.9 -36.9 29.0 0.387 0.066 B:Q02078:0.067
 DA
DT
DT
DA
DA
DT
 7.563
5.199
3.536
9.974
8.870
8.067
 O
CA
CA
N
O
O
 O3'
C3'
OP2
OP2
O3'
OP1
GLY B:26 B:27 33.0 0.44 H -53.3 -37.5 28.0 0.373 0.067 A:Q02078:0.067
 DT
DT
DA
DA
DT
DA
 8.838
8.222
7.605
5.096
3.421
9.971
 O
O
O
CA
CA
N
 O3'
OP1
O3'
C3'
OP2
OP2
GLY E:26 C:27 33.0 0.44 H -51.6 -37.2 NA NA NA
GLY F:26 D:27 33.0 0.44 H -52.6 -37.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q06413-f1 1 Q06413 100.0 0.0 GLY A:27 A:27 34.0 0.453 H -60.5 -40.6