Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 88119563 . G A CCDS47244.1:NM_001131005.2:c.43Cgt>Tgt_NP_001124477.1:p.15R>C Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5f28 1 Q8CFN5 97.8 5e-59 X-RAY
 2016-07-13 ARG A:15 NA:NA DO NA DO DO DO NA NA NA
ARG B:15 NA:NA DO NA DO DO DO NA NA NA
ARG C:15 NA:NA DO NA DO DO DO NA NA NA
ARG D:15 NA:NA DO NA DO DO DO NA NA NA
3kov 1 Q02078 96.67 1e-57 X-RAY
 2010-02-16 ARG A:14 A:15 194.0 0.862 H -93.8 -54.1 194.0 0.862 0.0 DA
DA
DT
 8.386
8.593
8.080
 O
C
O
 OP2
N7
N3
ARG B:14 B:15 195.0 0.867 H -90.4 -53.8 195.0 0.867 0.0 DA
DA
DG
DT
DT
 9.112
9.331
9.585
6.840
9.985
 O
O
O
O
O
 OP2
N7
O6
C7
C7
ARG C:14 I:15 200.0 0.889 H -92.1 -54.5 NA NA NA
ARG D:14 J:15 198.0 0.88 H -84.5 -55.2 NA NA NA
3p57 1 Q02078 96.67 1e-57 X-RAY
 2011-08-10 ARG A:14 A:15 194.0 0.862 H -60.3 -51.9 194.0 0.862 0.0 DA
DG
DA
DT
DT
HOH
 9.762
8.202
7.307
4.048
7.835
6.790
 CD
CD
CD
NH1
CD
CD
 C8
N7
N6
C7
O4
O
ARG B:14 B:15 200.0 0.889 H -59.8 -51.5 200.0 0.889 0.0 DA
DA
DA
DG
DT
DT
HOH
 7.128
9.658
9.931
9.315
7.657
7.573
2.912
 CD
CD
O
O
CD
CD
NE
 N6
N6
OP2
N7
C7
O4
O
ARG C:14 C:15 194.0 0.862 H -70.8 -40.5 194.0 0.862 0.0 DA
DA
DA
DG
DT
DT
HOH
 6.642
8.662
9.843
9.620
7.293
8.432
3.715
 NH1
CD
O
C
CD
CD
CD
 N7
N6
OP2
OP2
C7
O4
O
ARG D:14 D:15 197.0 0.876 H -63.4 -48.1 197.0 0.876 0.0 DG
DA
DT
DC
HOH
 8.122
5.850
4.047
9.384
4.229
 NH1
NH1
NH1
NH1
CG
 O6
N6
C7
N4
O
ARG E:14 I:15 200.0 0.889 H -62.5 -48.1 200.0 0.889 0.0 DA
DA
DA
DT
DT
HOH
 8.385
9.968
9.943
8.347
7.624
5.141
 NH1
O
O
CD
CD
N
 N6
N6
OP2
C7
C7
O
ARG F:14 J:15 192.0 0.853 H -61.1 -49.3 192.0 0.853 0.0 DA
DA
DG
DA
DT
DT
HOH
 9.327
9.883
9.396
9.959
4.991
8.161
7.825
 O
C
CD
CD
NH1
NH1
O
 OP2
OP2
O6
N6
C7
C7
O
6byy 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2018-01-31 ARG A:15 A:15 206.0 0.916 H -72.1 -41.0 206.0 0.916 0.0 DA
DG
DT
DT
HOH
 8.569
9.986
9.877
8.890
2.701
 NH2
C
NH2
NH2
O
 N6
OP2
C7
O4
O
ARG B:15 B:15 194.0 0.862 H -66.2 -40.8 194.0 0.862 0.0 DA
DA
DG
DA
DT
HOH
 9.620
9.791
9.906
9.623
8.590
3.018
 O
C
CD
CD
CD
N
 OP2
OP2
O6
N6
O4
O
ARG C:15 C:15 211.0 0.938 H -104.0 -46.1 NA NA NA
ARG D:15 D:15 160.0 0.711 H -44.7 -57.2 NA NA NA
6wc2 1 Q02078,Q02080 89.47 3e-57 X-RAY
 2020-07-22 ARG A:15 A:15 177.0 0.787 H -66.0 -48.2 177.0 0.787 0.0 DG
DT
DG
DC
DA
HOH
 9.680
7.348
7.159
5.522
8.189
3.273
 C
NH2
NH2
NH2
NH2
NH1
 OP2
O4
O6
N4
N6
O
ARG B:15 B:15 194.0 0.862 H -66.2 -48.9 112.0 0.498 0.364 O:P52952:0.364
 DC
DA
DC
DT
DT
DA
HOH
 7.230
3.934
3.373
7.263
9.597
9.101
2.492
 NH1
NH1
CD
O
O
O
O
 O3'
C2'
O5'
OP2
C7
OP2
O
ARG C:15 C:15 200.0 0.889 H -67.1 -46.3 NA NA NA
ARG D:15 D:15 190.0 0.844 H -64.1 -49.3 NA NA NA
ARG I:15 I:15 202.0 0.898 H -60.8 -49.3 NA NA NA
ARG J:15 J:15 205.0 0.911 H -66.6 -46.9 NA NA NA
1tqe 3 Q02080 86.02 8e-56 X-RAY
 2004-12-21 ARG E:15 P:15 183.0 0.813 T -70.6 -57.0 183.0 0.813 0.0 DT
DT
DG
 3.416
7.759
9.867
 CB
CB
O
 C7
C7
O6
ARG F:15 Q:15 184.0 0.818 T -71.3 -56.4 184.0 0.818 0.0 DA
DA
DG
 6.227
8.502
9.671
 O
O
C
 C5'
C2
OP2
ARG H:15 R:15 181.0 0.804 T -70.4 -57.5 NA NA NA
ARG I:15 S:15 184.0 0.818 T -71.1 -56.9 NA NA NA
6c9l 1 Q02080 86.02 8e-56 X-RAY
 2018-02-07 ARG A:15 A:15 201.0 0.893 H -72.4 -42.0 201.0 0.893 0.0 HOH
 3.053
 N
 O
ARG B:15 B:15 216.0 0.96 G -49.6 -44.1 216.0 0.96 0.0 HOH
 3.018
 NE
 O
ARG C:15 C:15 212.0 0.942 G -49.5 -43.9 NA NA NA
ARG D:15 D:15 198.0 0.88 H -72.3 -41.8 NA NA NA
ARG E:15 E:15 192.0 0.853 H -72.4 -41.5 NA NA NA
ARG F:15 F:15 200.0 0.889 H -72.3 -41.5 NA NA NA
6bz1 1 Q02078,Q02080 88.42 9e-56 X-RAY
 2018-02-07 ARG A:15 C:15 179.0 0.796 H -71.1 -35.5 179.0 0.796 0.0 DA
DA
DT
DC
 9.804
9.689
7.356
9.911
 O
O
O
O
 N7
N6
C7
N4
ARG B:15 D:15 196.0 0.871 H -69.9 -37.1 196.0 0.871 0.0 DA
DG
DT
 8.965
9.768
8.724
 CD
O
O
 OP2
N7
C7
ARG E:15 A:15 191.0 0.849 H -69.8 -37.2 NA NA NA
ARG F:15 B:15 191.0 0.849 H -71.4 -35.5 NA NA NA
1n6j 3 Q02080 85.87 6e-55 X-RAY
 2003-11-11 ARG C:14 A:15 195.0 0.867 H -65.8 -46.5 195.0 0.867 0.0 DA
DA
DG
DC
DT
HOH
 8.246
9.745
9.791
9.322
8.968
4.864
 O
O
C
O
O
N
 N6
OP2
OP2
N4
O4
O
ARG D:14 B:15 195.0 0.867 H -65.5 -46.1 195.0 0.867 0.0 DA
DA
DG
DC
DG
HOH
 9.988
9.620
9.086
9.351
8.684
2.798
 O
O
O
CB
CB
CG
 OP2
N7
O6
N4
O6
O
6wc5 1 Q02080 86.67 8e-54 X-RAY
 2020-07-22 ARG A:14 A:15 168.0 0.747 H -70.5 -47.2 168.0 0.747 0.0 DA
DG
DT
DG
DC
DA
 9.960
9.667
7.715
7.615
7.013
9.627
 O
C
O
NH2
NH2
NH2
 OP2
OP2
C7
O6
N4
N6
ARG B:14 B:15 175.0 0.778 H -71.4 -46.2 93.0 0.413 0.365 I:P52952:0.364
 DC
DA
DC
DT
DT
DA
 7.325
4.787
3.029
6.452
9.080
8.968
 NH1
NH1
CD
CB
O
O
 O3'
O3'
OP2
OP2
C7
OP2
ARG C:14 C:15 170.0 0.756 H -60.8 -43.0 NA NA NA
ARG D:14 D:15 172.0 0.764 H -71.2 -46.1 NA NA NA
1egw 3 Q02078 98.7 9e-50 X-RAY
 2000-03-20 ARG E:14 A:15 194.0 0.862 H -61.5 -50.3 194.0 0.862 0.0 DA
DA
DA
DG
DC
DT
DT
DT
DA
DA
DG
DC
DT
DT
HOH
 3.567
2.528
5.993
8.914
7.940
8.075
9.159
3.841
3.299
6.493
8.275
8.659
7.118
7.820
2.666
 NH2
NH1
NH2
NH2
NE
NH2
NH2
NH2
NH1
NH2
NH2
NE
NH2
NH2
NH2
 C2'
OP2
N6
O6
N4
O4
O4
C2'
OP2
N7
O6
N4
O4
O4
O
ARG F:14 B:15 194.0 0.862 H -64.4 -47.7 194.0 0.862 0.0 DG
DA
DG
HOH
 9.552
9.543
9.524
2.830
 C
O
O
O
 OP2
OP2
N7
O
ARG G:14 C:15 191.0 0.849 H -62.5 -51.3 NA NA NA
ARG H:14 D:15 195.0 0.867 H -60.9 -49.9 NA NA NA
3mu6 1 Q02078 97.18 2e-43 X-RAY
 2011-11-02 ARG A:14 A:15 186.0 0.827 H -69.4 -58.8 186.0 0.827 0.0 DC
DT
DT
DA
DA
 9.165
9.485
5.409
3.465
9.383
 CG
CD
NH2
NH2
NE
 N4
O4
O3'
OP2
N7
ARG B:14 B:15 187.0 0.831 H -70.7 -59.5 187.0 0.831 0.0 DA
DA
DA
DC
DT
 5.439
3.542
9.324
9.254
9.641
 NH2
NH2
CD
CG
CD
 C3'
OP2
N6
N4
O4
ARG E:14 C:15 187.0 0.831 H -70.3 -59.2 NA NA NA
ARG F:14 D:15 187.0 0.831 H -70.7 -59.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q06413-f1 1 Q06413 100.0 0.0 ARG A:15 A:15 202.0 0.898 H -65.7 -49.5