Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 170881294 . A C CCDS5315.1:NM_003194.4:c.961Att>Ctt_NP_003185.1:p.321I>L Homo sapiens TATA-box binding protein (TBP), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 100.0 0.0 EM
 2016-04-06 ILE A:321 A:321 0.0 0.0 H -65.2 -47.8 0.0 0.0 0.0 DA
DA
 9.383
9.991
 CD1
CD1
 N3
N3
5iy6 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 0.0 0.0 H -65.1 -48.4 0.0 0.0 0.0
5iy7 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 2.0 0.011 H -65.7 -48.4 2.0 0.011 0.0 DA
 9.918
 CD1
 O4'
5iy8 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 3.0 0.017 H -63.5 -47.7 3.0 0.017 0.0
5iy9 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 6.0 0.034 H -62.7 -49.7 6.0 0.034 0.0 DA
 9.740
 CD1
 O4'
5iya 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 0.0 0.0 H -65.1 -48.3 0.0 0.0 0.0 DA
 9.938
 CD1
 O4'
5iyb 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 5.0 0.029 H -65.7 -48.3 5.0 0.029 0.0 DA
 9.917
 CD1
 O4'
5iyc 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 3.0 0.017 H -63.4 -47.8 3.0 0.017 0.0
5iyd 16 P20226 100.0 0.0 EM
 2016-05-18 ILE P:321 P:321 6.0 0.034 H -62.7 -49.7 6.0 0.034 0.0 DA
 9.740
 CD1
 O4'
6mzd 11 P20226 100.0 0.0 EM
 2018-11-28 ILE K:321 T:321 0.0 0.0 H -64.6 -47.4 0.0 0.0 0.0
6mzl 15 P20226 100.0 0.0 EM
 2018-11-28 ILE T:321 T:321 0.0 0.0 H -64.6 -47.4 0.0 0.0 0.0
6mzm 12 P20226 100.0 0.0 EM
 2018-11-28 ILE L:321 T:321 0.0 0.0 H -64.3 -47.4 0.0 0.0 0.0 DA
 8.921
 CD1
 O4'
6o9l 16 P20226 100.0 0.0 EM
 2019-05-29 ILE P:321 P:321 0.0 0.0 H -73.2 -43.5 0.0 0.0 0.0
7edx 12 P20226 100.0 0.0 EM
 2021-05-05 ILE L:321 P:321 0.0 0.0 H -60.0 -46.7 0.0 0.0 0.0 DT
DA
 9.775
9.268
 CD1
CD1
 O2
N3
7eg7 12 P20226 100.0 0.0 EM
 2021-05-05 ILE L:321 P:321 0.0 0.0 H -60.0 -46.6 0.0 0.0 0.0
7eg8 12 P20226 100.0 0.0 EM
 2021-05-05 ILE L:321 P:321 0.0 0.0 H -60.0 -46.7 0.0 0.0 0.0 DG
DT
 9.412
8.599
 CD1
CD1
 N2
O2
7eg9 12 P20226 100.0 0.0 EM
 2021-05-05 ILE L:321 P:321 0.0 0.0 H -60.0 -46.7 0.0 0.0 0.0 DA
DT
 9.687
9.138
 CD1
CD1
 N3
O2
7ega 12 P20226 100.0 0.0 EM
 2021-05-05 ILE L:321 P:321 0.0 0.0 H -60.1 -46.6 0.0 0.0 0.0 DG
DT
 9.424
8.556
 CD1
CD1
 N2
O2
7egb 22 P20226 100.0 0.0 EM
 2021-05-05 ILE V:321 P:321 1.0 0.006 H -64.9 -40.5 1.0 0.006 0.0 DA
 9.883
 CD1
 N3
7egc 22 P20226 100.0 0.0 EM
 2021-05-12 ILE V:321 P:321 6.0 0.034 H -57.1 -45.5 6.0 0.034 0.0 DT
 9.658
 CD1
 O2
7egd 12 P20226 100.0 0.0 EM
 2021-05-12 ILE L:321 P:321 2.0 0.011 H -64.9 -40.4 2.0 0.011 0.0 DA
DT
 9.277
9.517
 CD1
CD1
 OP1
OP1
7ege 11 P20226 100.0 0.0 EM
 2021-05-12 ILE K:321 P:321 2.0 0.011 H -65.0 -40.4 2.0 0.011 0.0
7egf 1 P20226 100.0 0.0 EM
 2021-05-05 ILE A:321 P:321 2.0 0.011 H -65.0 -40.4 2.0 0.011 0.0
7egi 12 P20226 100.0 0.0 EM
 2021-05-12 ILE L:321 P:321 1.0 0.006 H -64.9 -40.4 1.0 0.006 0.0
7egj 12 P20226 100.0 0.0 EM
 2021-05-12 ILE L:321 P:321 1.0 0.006 H -65.0 -40.5 1.0 0.006 0.0 DA
 9.426
 CD1
 OP1
7ena 5 P20226 100.0 0.0 EM
 2021-05-26 ILE E:321 DP:321 0.0 0.0 H -59.9 -46.7 0.0 0.0 0.0 DA
DA
 8.623
9.072
 CD1
CD1
 N3
C5'
7enc 49 P20226 100.0 0.0 EM
 2021-05-26 ILE CB:321 DP:321 0.0 0.0 H -61.6 -46.4 0.0 0.0 0.0 DA
DA
 8.525
9.740
 CD1
CD1
 O4'
C5'
7lbm 20 P20226 100.0 0.0 EM
 2021-03-24 ILE T:321 P:321 2.0 0.011 H -66.6 -33.1 2.0 0.011 0.0 DA
DA
 9.746
9.973
 CD1
CD1
 O4'
O4'
7nvr 25 P20226 100.0 0.0 EM
 2021-05-05 ILE Y:321 O:321 0.0 0.0 H -59.8 -50.2 0.0 0.0 0.0 DA
 9.164
 CD1
 N3
7nvs 15 P20226 100.0 0.0 EM
 2021-05-05 ILE O:321 O:321 0.0 0.0 H -61.0 -49.2 0.0 0.0 0.0 DA
DT
 9.108
9.981
 CD1
CD1
 N3
O2
7nvt 15 P20226 100.0 0.0 EM
 2021-05-05 ILE O:321 O:321 0.0 0.0 H -60.9 -48.9 0.0 0.0 0.0 DA
 9.021
 CD1
 O4'
7nvu 15 P20226 100.0 0.0 EM
 2021-05-05 ILE O:321 O:321 0.0 0.0 H -59.4 -47.5 0.0 0.0 0.0 DA
 9.339
 CD1
 C1'
7nvy 23 P20226 100.0 0.0 EM
 2021-05-05 ILE W:321 O:321 0.0 0.0 H -60.3 -48.7 0.0 0.0 0.0 DA
DT
 9.033
9.963
 CD1
CD1
 N3
O2
7nvz 23 P20226 100.0 0.0 EM
 2021-05-05 ILE W:321 O:321 0.0 0.0 H -59.9 -49.5 0.0 0.0 0.0 DA
 8.988
 CD1
 O4'
7nw0 23 P20226 100.0 0.0 EM
 2021-05-05 ILE W:321 O:321 0.0 0.0 H -59.5 -47.6 0.0 0.0 0.0 DA
 9.359
 CD1
 C1'
1jfi 5 P20226 98.38 5e-134 X-RAY
 2001-07-11 ILE E:167 C:521 1.0 0.006 H -70.4 -42.2 1.0 0.006 0.0 DA
DA
HOH
 9.424
9.910
6.857
 CD1
CD1
CG2
 N3
N3
O
1tgh 2 P20226 98.38 6e-134 X-RAY
 1996-08-01 ILE C:167 A:317 0.0 0.0 H -62.1 -48.6 0.0 0.0 0.0 DA
HOH
 9.949
8.515
 CD1
CG2
 N3
H2
5n9g 2 P20226 100.0 1e-133 X-RAY
 2017-06-14 ILE B:182 B:321 0.0 0.0 H -66.7 -49.3 0.0 0.0 0.0 DT
DT
A
A
HOH
 9.871
9.758
9.979
9.055
7.336
 CD1
CD1
CD1
CD1
N
 O2
O2
N3
C1'
O
ILE G:182 G:321 0.0 0.0 H -66.4 -49.2 NA NA NA
1nvp 3 P20226 100.0 2e-133 X-RAY
 2003-10-21 ILE C:163 A:321 0.0 0.0 H -65.7 -48.3 0.0 0.0 0.0 DA
DA
HOH
 9.237
9.903
4.817
 CD1
CD1
O
 N3
N3
O
4roc 2 P20226 100.0 5e-133 X-RAY
 2015-12-30 ILE B:165 B:321 0.0 0.0 H -68.2 -48.3 0.0 0.0 0.0 DA
DA
DT
DT
HOH
 9.918
9.130
9.956
9.526
6.236
 CD1
CD1
CD1
CD1
C
 N3
N3
O2
O2
O
4rod 2 P20226 100.0 5e-133 X-RAY
 2015-12-30 ILE B:165 B:321 0.0 0.0 H -68.9 -47.9 0.0 0.0 0.0 DA
DT
DA
HOH
 9.109
9.919
9.851
6.451
 CD1
CD1
CD1
C
 O4'
O2
N3
O
4roe 2 P20226 100.0 5e-133 X-RAY
 2015-12-30 ILE B:165 B:321 0.0 0.0 H -71.9 -46.9 0.0 0.0 0.0 DT
DA
DT
DA
HOH
 9.738
8.804
9.857
9.587
6.715
 CD1
CD1
CD1
CD1
CG2
 O2
O4'
O2
N3
O
1c9b 4 P20226 99.44 1e-131 X-RAY
 2000-01-10 ILE L:164 B:321 0.0 0.0 H -65.1 -50.2 0.0 0.0 0.0 DT
DA
DT
DA
HOH
 9.772
8.939
9.830
9.671
5.909
 CD1
CD1
CD1
CD1
O
 O2
O4'
O2
N3
O
ILE N:164 F:321 0.0 0.0 H -66.1 -48.3 NA NA NA
ILE P:164 J:321 0.0 0.0 H -68.9 -47.1 NA NA NA
ILE R:164 N:321 0.0 0.0 H -66.5 -49.9 NA NA NA
ILE T:164 R:321 0.0 0.0 H -63.5 -53.4 NA NA NA
1cdw 3 P20226 99.44 3e-131 X-RAY
 1996-12-23 ILE C:163 A:317 0.0 0.0 H -68.5 -43.4 0.0 0.0 0.0 HOH
 4.590
 N
 O
1vto 3 P28147 80.21 8e-111 X-RAY
 2011-07-13 THR E:171 A:181 0.0 0.0 H -59.6 -45.7 0.0 0.0 0.0 DA
HOH
 9.828
2.007
 HG1
HG1
 O4'
O
THR F:171 B:1181 0.0 0.0 H -56.2 -49.0 NA NA NA
1vtl 3 P28147 83.24 1e-110 X-RAY
 2011-07-13 THR E:169 E:181 0.0 0.0 H -58.3 -47.1 0.0 0.0 0.0 DA
 9.857
 HG1
 N3
THR F:169 F:181 0.0 0.0 H -62.3 -41.5 NA NA NA
6tb4 1 ? 80.22 2e-110 EM
 2020-01-29 ILE A:226 M:223 0.0 0.0 H -73.0 -47.3 0.0 0.0 0.0
4v1n 15 P13393 81.01 2e-109 EM
 2015-02-04 ILE O:164 O:223 0.0 0.0 H -63.3 -48.3 0.0 0.0 0.0 DA
DT
DA
 8.884
9.923
9.767
 CD1
CD1
CD1
 O4'
O2
N3
4v1o 15 P13393 81.01 2e-109 EM
 2015-02-04 ILE O:164 O:223 0.0 0.0 H -63.3 -48.3 0.0 0.0 0.0 DA
DT
DA
 8.884
9.923
9.767
 CD1
CD1
CD1
 O4'
O2
N3
1ngm 3 P13393 81.01 3e-109 X-RAY
 2003-03-25 ILE I:163 A:223 0.0 0.0 H -43.8 -49.1 0.0 0.0 0.0 DA
DT
 9.744
9.701
 CD1
CD1
 O4'
O2
ILE K:163 E:223 0.0 0.0 H -61.0 -48.8 NA NA NA
ILE M:163 I:223 0.0 0.0 H -57.7 -58.8 NA NA NA
ILE O:163 M:223 0.0 0.0 H -55.6 -48.1 NA NA NA
1nh2 3 P13393 81.01 3e-109 X-RAY
 2003-10-21 ILE C:163 A:223 0.0 0.0 H -63.7 -46.8 0.0 0.0 0.0 DA
DA
HOH
 8.975
9.904
5.075
 CD1
CD1
O
 O4'
N3
O
1ytb 2 P13393 81.01 3e-109 X-RAY
 1995-01-26 ILE C:163 A:223 0.0 0.0 H -63.4 -48.3 0.0 0.0 0.0 DA
DA
HOH
 9.230
9.905
5.571
 CD1
CD1
O
 N3
N3
O
ILE D:163 B:223 0.0 0.0 H -67.7 -41.9 NA NA NA
1ytf 3 P13393 81.01 3e-109 X-RAY
 1996-06-20 ILE C:163 A:223 0.0 0.0 H -61.9 -48.8 0.0 0.0 0.0 DA
DT
DA
 8.920
9.829
9.872
 CD1
CD1
CD1
 O4'
O2
N3
5fmf 19 P13393 81.01 3e-109 EM
 2015-11-25 ILE S:163 Q:223 0.0 0.0 H -64.0 -46.6 0.0 0.0 0.0 DA
 8.867
 CD1
 O4'
1tbp 1 P13393 80.9 1e-108 X-RAY
 1994-01-31 ILE A:163 A:223 0.0 0.0 H -73.1 -47.3 0.0 0.0 0.0
ILE B:163 B:223 0.0 0.0 H -69.4 -43.7 0.0 0.0 0.0
6e24 1 P46677,P01106,P13393 80.79 7e-107 X-RAY
 2019-10-02 ILE A:242 A:423 4.0 0.023 H -65.6 -49.1 4.0 0.023 0.0
6e16 1 P46677,P01106,P13393 80.79 1e-106 X-RAY
 2019-10-02 ILE A:250 A:423 3.0 0.017 H -57.9 -48.0 3.0 0.017 0.0 HOH
 7.821
 CG1
 O
4b0a 1 P46677,P13393 80.79 3e-106 X-RAY
 2013-07-03 ILE A:261 A:323 0.0 0.0 H -66.0 -46.0 0.0 0.0 0.0 GOL
HOH
 8.877
7.890
 CD1
N
 O3
O
6cnb 18 P29056,P13393 81.01 1e-104 EM
 2018-08-22 ILE R:549 R:549 1.0 0.006 H -53.0 -63.4 1.0 0.006 0.0
6cnc 18 P29056,P13393 81.01 1e-104 EM
 2018-08-22 ILE R:549 R:549 3.0 0.017 H -55.0 -62.3 3.0 0.017 0.0
6cnd 18 P29056,P13393 81.01 1e-104 EM
 2018-08-22 ILE R:549 R:549 6.0 0.034 H -47.8 -61.9 6.0 0.034 0.0
6cnf 18 P29056,P13393 81.01 1e-104 EM
 2018-08-22 ILE R:549 R:549 1.0 0.006 H -51.3 -61.5 1.0 0.006 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20226-f1 1 P20226 100.0 0.0 ILE A:321 A:321 1.0 0.006 H -69.1 -42.4