Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 32548628 . G A CCDS47409.1:NM_002124.3:c.658Cgg>Tgg_NP_002115.2:p.220R>W Homo sapiens major histocompatibility complex, class II, DR beta 1 (HLA-DRB1), transcript variant 1, mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wbj 2 P01911 99.5 7e-150 X-RAY
 2009-04-07 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
ARG F:191 NA:NA DO NA DO DO DO NA NA NA
1ymm 2 Q29790 100.0 9e-150 X-RAY
 2005-05-03 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1bx2 2 P04229 100.0 3e-144 X-RAY
 1998-10-21 ARG B:189 B:191 158.0 0.702 -120.8 136.3 158.0 0.702 0.0 HOH
 2.718
 CD
 O
ARG E:189 E:191 120.0 NA -32.5 360.0 120.0 NA NA
3pdo 2 P04229 93.43 9e-138 X-RAY
 2010-12-08 ARG B:192 NA:NA DO NA DO DO DO NA NA NA
3pgc 2 P04229 93.43 9e-138 X-RAY
 2010-12-08 ARG B:192 B:191 98.0 NA -112.7 160.8 98.0 NA NA HOH
 3.105
 CA
 O
ARG E:192 NA:NA DO NA DO DO DO NA NA NA
3pgd 2 P04229 93.43 9e-138 X-RAY
 2010-12-08 ARG B:192 NA:NA DO NA DO DO DO NA NA NA
ARG E:192 NA:NA DO NA DO DO DO NA NA NA
4aen 2 P04229 93.43 9e-138 X-RAY
 2012-08-01 ARG B:192 NA:NA DO NA DO DO DO NA NA NA
4x5w 2 P04229 93.43 9e-138 X-RAY
 2016-03-09 ARG B:192 B:191 194.0 0.862 -55.2 143.4 194.0 0.862 0.0 HOH
 3.873
 O
 O
1aqd 2 P04229 93.43 9e-138 X-RAY
 1998-01-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
ARG E:191 NA:NA DO NA DO DO DO NA NA NA
ARG H:191 NA:NA DO NA DO DO DO NA NA NA
ARG K:191 K:191 210.0 0.933 -36.1 360.0 NA NA NA
4ah2 2 P04233,P04229 93.4 4e-137 X-RAY
 2012-08-01 ARG B:222 NA:NA DO NA DO DO DO NA NA NA
4x5x 2 P04229 92.89 1e-135 X-RAY
 2016-03-09 ARG B:222 NA:NA DO NA DO DO DO NA NA NA
ARG D:222 NA:NA DO NA DO DO DO NA NA NA
4fqx 5 P04229 89.6 1e-133 X-RAY
 2013-01-09 ARG E:197 NA:NA DO NA DO DO DO NA NA NA
4gbx 4 P04229 89.6 1e-133 X-RAY
 2013-01-16 ARG D:197 NA:NA DO NA DO DO DO NA NA NA
4i5b 2 P04229 93.23 1e-133 X-RAY
 2013-12-04 ARG B:190 B:191 194.0 0.862 -54.0 138.5 194.0 0.862 0.0 HOH
 6.855
 N
 O
ARG E:190 E:191 219.0 0.973 -162.2 360.0 NA NA NA
3l6f 2 P04229 93.23 3e-133 X-RAY
 2010-05-12 ARG B:192 NA:NA DO NA DO DO DO NA NA NA
3s4s 2 P04229 93.23 3e-133 X-RAY
 2011-09-21 ARG B:192 NA:NA DO NA DO DO DO NA NA NA
ARG F:192 NA:NA DO NA DO DO DO NA NA NA
3s5l 2 P04229 93.23 3e-133 X-RAY
 2011-09-21 ARG C:192 NA:NA DO NA DO DO DO NA NA NA
ARG D:192 NA:NA DO NA DO DO DO NA NA NA
1fyt 2 P04229 93.23 3e-133 X-RAY
 2000-11-08 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1seb 2 P04229 93.23 3e-133 X-RAY
 1996-06-20 ARG B:191 B:191 167.0 0.742 -13.9 111.6 167.0 0.742 0.0
ARG F:191 F:191 166.0 0.738 -14.0 111.6 166.0 0.738 0.0
1d5m 2 P13760 91.67 1e-131 X-RAY
 2000-06-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1j8h 2 P13760 91.67 1e-131 X-RAY
 2002-03-13 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1d5x 2 P13760 91.15 4e-131 X-RAY
 2000-06-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1d5z 2 P13760 91.15 4e-131 X-RAY
 2000-06-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
1d6e 2 P13760 91.15 4e-131 X-RAY
 2000-06-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
2seb 2 P13760 91.15 4e-131 X-RAY
 1998-01-28 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
4is6 2 P13760 91.15 4e-131 X-RAY
 2013-10-23 ARG B:191 NA:NA DO NA DO DO DO NA NA NA
4md5 2 P13760 88.44 5e-131 X-RAY
 2013-12-04 THR B:193 B:191 162.0 1.0 -87.2 360.0 162.0 1.0 0.0 EDO
HOH
 7.004
3.189
 CG2
N
 O2
O
6bix 2 Q29890 88.44 5e-131 X-RAY
 2018-01-17 THR B:193 NA:NA DO NA DO DO DO NA NA NA
6biy 2 Q29890 88.44 5e-131 X-RAY
 2018-01-17 THR B:193 NA:NA DO NA DO DO DO NA NA NA
6biz 2 Q29890 88.44 5e-131 X-RAY
 2018-01-17 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4mdi 2 P13760 88.44 7e-131 X-RAY
 2013-12-04 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4mdj 2 P13760 88.44 7e-131 X-RAY
 2013-12-04 THR B:193 B:191 106.0 0.757 T -107.7 23.4 106.0 0.757 0.0 HOH
 2.746
 OG1
 O
4mcy 2 P13760 87.94 3e-130 X-RAY
 2013-11-27 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4mcz 2 P13760 87.94 3e-130 X-RAY
 2013-12-04 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4md0 2 P13760 87.94 3e-130 X-RAY
 2013-12-04 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4md4 2 P13760 87.94 3e-130 X-RAY
 2013-12-04 THR B:193 NA:NA DO NA DO DO DO NA NA NA
4y19 2 P13760 87.94 3e-130 X-RAY
 2015-09-23 THR B:193 B:191 120.0 NA -108.8 360.0 120.0 NA NA
4y1a 2 P13760 87.94 3e-130 X-RAY
 2015-09-23 THR B:193 B:191 176.0 1.0 -111.9 360.0 176.0 1.0 0.0
6bil 2 P13760 87.94 3e-130 X-RAY
 2018-01-17 THR B:193 NA:NA DO NA DO DO DO NA NA NA
6bin 3 P13760 87.94 3e-130 X-RAY
 2018-01-17 THR C:193 NA:NA DO NA DO DO DO NA NA NA
6biv 2 P13760 87.94 3e-130 X-RAY
 2018-01-17 THR B:193 NA:NA DO NA DO DO DO NA NA NA
6nix 2 P13760 87.94 3e-130 X-RAY
 2020-01-22 THR B:193 NA:NA DO NA DO DO DO NA NA NA
5jlz 2 P13760 90.62 4e-130 X-RAY
 2016-12-07 SER B:191 B:191 73.0 0.635 S -100.5 174.1 73.0 0.635 0.0 HOH
 6.122
 N
 O
SER D:191 D:191 89.0 0.774 -169.6 360.0 NA NA NA
5lax 2 P13760 90.62 4e-130 X-RAY
 2016-12-07 SER B:191 B:191 67.0 0.583 S -161.6 174.5 67.0 0.583 0.0 HOH
 5.767
 OG
 O
SER D:191 D:191 93.0 0.809 -147.1 360.0 NA NA NA
5ni9 2 P13760 90.62 4e-130 X-RAY
 2018-06-13 SER B:191 B:191 66.0 0.574 G -65.1 -16.3 66.0 0.574 0.0 HOH
 6.644
 C
 O
5nig 2 P13760 90.62 4e-130 X-RAY
 2018-06-13 SER B:191 B:191 64.0 0.557 G -68.6 -9.3 64.0 0.557 0.0 HOH
 2.932
 N
 O
6v0y 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
6v13 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
6v15 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
6v18 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
6v19 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
6v1a 2 P13760 87.88 2e-129 X-RAY
 2020-11-25 THR B:191 NA:NA DO NA DO DO DO NA NA NA
3o6f 2 P13760 91.1 3e-129 X-RAY
 2011-03-02 ARG B:220 NA:NA DO NA DO DO DO NA NA NA
ARG F:220 NA:NA DO NA DO DO DO NA NA NA
3t0e 2 P13760 91.1 3e-129 X-RAY
 2012-03-07 ARG B:220 NA:NA DO NA DO DO DO NA NA NA
1zgl 2 Q29787 88.54 2e-126 X-RAY
 2005-10-18 GLN B:191 NA:NA DO NA DO DO DO NA NA NA
GLN G:191 NA:NA DO NA DO DO DO NA NA NA
GLN L:191 NA:NA DO NA DO DO DO NA NA NA
GLN Q:191 NA:NA DO NA DO DO DO NA NA NA
1a6a 2 P01912 90.37 2e-126 X-RAY
 1998-05-27 ARG B:187 B:191 129.0 0.573 -47.3 360.0 129.0 0.573 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01911-f1 1 P01911 100.0 0.0 ARG A:220 A:220 138.0 0.613 -93.1 133.3
af-q30154-f1 1 Q30154 88.72 5e-168 GLN A:220 A:220 132.0 0.733 -68.2 127.8
af-p79483-f1 1 P79483 89.1 1e-167 ARG A:220 A:220 127.0 0.564 -91.9 133.7
af-p13762-f1 1 P13762 87.59 1e-166 ARG A:220 A:220 221.0 0.982 -71.8 127.3