Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541918 . C A CCDS4781.1:NM_001188.3:c.424Gtc>Ttc_NP_001179.1:p.142V>F Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 VAL A:127 A:142 1.0 0.006 H -69.9 -35.0 1.0 0.006 0.0 HOH
 3.668
 CG2
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 VAL A:127 A:142 2.0 0.013 H -61.4 -37.3 2.0 0.013 0.0 HOH
 3.683
 CG2
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 VAL A:124 A:142 4.0 0.026 H -66.8 -37.7 4.0 0.026 0.0 HOH
 3.531
 CG2
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 VAL A:125 A:142 10.0 0.065 H -82.4 -40.9 10.0 0.065 0.0
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 VAL A:122 A:142 5.0 0.032 H -66.5 -37.7 5.0 0.032 0.0 HOH
 3.873
 CG2
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 VAL A:125 A:142 17.0 0.11 H -69.0 -38.1 2.0 0.013 0.097 B:Q16611:0.097
 HOH
 6.621
 O
 O
VAL B:125 B:142 40.0 0.258 H -80.2 -5.6 1.0 0.006 0.252 A:Q16611:0.252
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 VAL A:120 A:142 3.0 0.019 H -71.2 -35.7 3.0 0.019 0.0 HOH
 4.908
 CB
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 13.0 0.084 H -64.9 -40.8 13.0 0.084 0.0 EDO
GOL
HOH
 8.858
5.270
5.617
 CG1
N
CG1
 HO2
H11
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 23.0 0.148 H -60.2 -33.2 7.0 0.045 0.103 B:Q16611:0.103
 HOH
 6.895
 N
 O
VAL B:126 B:142 20.0 0.129 H -59.7 -33.5 7.0 0.045 0.084 A:Q16611:0.084
 HOH
 3.692
 O
 O
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 13.0 0.084 H -65.9 -36.1 4.0 0.026 0.058 C:Q16611:0.058
 HOH
 6.668
 N
 O
VAL C:126 C:142 33.0 0.213 H -66.1 -41.4 11.0 0.071 0.142 A:Q16611:0.142
 HOH
 6.795
 O
 O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 12.0 0.077 H -66.3 -40.1 0.0 0.0 0.077 A:Q16611:0.077
 HOH
 6.108
 C
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 9.0 0.058 H -69.1 -36.8 9.0 0.058 0.0 HOH
 2.922
 O
 O
VAL C:126 C:142 7.0 0.045 H -64.6 -40.5 7.0 0.045 0.0 1PG
HOH
 6.504
2.921
 O
O
 O3
O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 VAL A:126 A:142 4.0 0.026 H -68.5 -34.5 4.0 0.026 0.0 MG
HOH
 6.643
3.903
 CB
CB
 MG
O
VAL C:126 C:142 4.0 0.026 H -67.4 -35.8 4.0 0.026 0.0 HOH
 3.576
 O
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 VAL A:122 A:142 3.0 0.019 H -68.3 -35.3 3.0 0.019 0.0 HOH
 3.887
 CG2
 O
VAL C:122 C:142 3.0 0.019 H -70.2 -34.9 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 VAL A:122 A:142 1.0 0.006 H -62.0 -32.9 1.0 0.006 0.0 CU
SO4
 7.408
7.974
 N
CG1
 CU
O3
VAL C:122 C:142 2.0 0.013 H -63.8 -32.8 NA NA NA
VAL E:122 E:142 3.0 0.019 H -62.3 -31.9 NA NA NA
VAL G:122 G:142 4.0 0.026 H -62.5 -31.2 NA NA NA
VAL I:122 I:142 2.0 0.013 H -62.3 -32.1 NA NA NA
VAL K:122 K:142 2.0 0.013 H -62.4 -32.0 NA NA NA
VAL M:122 M:142 2.0 0.013 H -62.6 -32.4 NA NA NA
VAL O:122 O:142 2.0 0.013 H -62.6 -33.2 NA NA NA
VAL Q:122 Q:142 2.0 0.013 H -62.5 -32.0 NA NA NA
VAL S:122 S:142 3.0 0.019 H -61.7 -33.0 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 VAL A:126 A:142 4.0 0.026 H -61.6 -37.5 4.0 0.026 0.0 HOH
 3.082
 O
 O
VAL B:126 B:142 8.0 0.052 H -65.5 -40.6 8.0 0.052 0.0 HOH
 2.708
 O
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 VAL A:120 A:142 9.0 0.058 H -66.1 -34.7 9.0 0.058 0.0 HOH
 2.981
 O
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 VAL A:78 A:142 6.0 0.039 H -74.1 -36.3 6.0 0.039 0.0
VAL B:78 B:142 32.0 0.206 H -70.4 -41.6 32.0 0.206 0.0
VAL C:78 C:142 10.0 0.065 H -70.8 -43.1 NA NA NA
VAL D:78 D:142 9.0 0.058 H -80.3 -26.8 NA NA NA
VAL E:78 E:142 34.0 0.219 H -68.9 -31.5 NA NA NA
VAL F:78 F:142 14.0 0.09 H -71.6 -26.8 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 24.0 0.155 H -69.2 -36.2 24.0 0.155 0.0
VAL B:79 B:142 28.0 0.181 H -70.3 -38.0 28.0 0.181 0.0
VAL C:79 C:142 31.0 0.2 H -64.8 -48.1 NA NA NA
VAL D:79 D:142 29.0 0.187 H -70.0 -36.2 NA NA NA
VAL E:79 E:142 30.0 0.194 H -70.1 -36.6 NA NA NA
VAL F:79 F:142 26.0 0.168 H -69.6 -38.1 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 27.0 0.174 H -67.2 -32.2 27.0 0.174 0.0 HOH
 6.324
 N
 O
VAL B:79 B:142 19.0 0.123 H -70.1 -41.5 19.0 0.123 0.0 8SP
HOH
 6.701
4.367
 CG1
CG1
 N
O
VAL C:79 C:142 28.0 0.181 H -64.7 -38.1 NA NA NA
VAL D:79 D:142 28.0 0.181 H -72.0 -41.0 NA NA NA
VAL E:79 E:142 27.0 0.174 H -67.1 -36.1 NA NA NA
VAL F:79 F:142 15.0 0.097 H -70.8 -40.2 NA NA NA
VAL G:79 G:142 29.0 0.187 H -67.7 -36.6 NA NA NA
VAL H:79 H:142 29.0 0.187 H -73.6 -40.4 NA NA NA
VAL I:79 I:142 27.0 0.174 H -61.6 -37.9 NA NA NA
VAL J:79 J:142 20.0 0.129 H -71.3 -35.9 NA NA NA
VAL K:79 K:142 28.0 0.181 H -67.2 -40.1 NA NA NA
VAL L:79 L:142 17.0 0.11 H -66.7 -44.5 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 25.0 0.161 H -54.6 -47.5 25.0 0.161 0.0 SO4
EDO
HOH
 5.935
6.942
5.631
 N
C
N
 O4
C2
O
VAL B:79 B:142 15.0 0.097 H -64.3 -39.9 15.0 0.097 0.0 LMT
LMT
SO4
EDO
HOH
 9.396
6.845
6.788
8.952
5.142
 N
CG2
N
CB
CG1
 O6B
C5
O1
O2
O
VAL C:79 C:142 25.0 0.161 H -66.9 -39.8 NA NA NA
VAL D:79 D:142 17.0 0.11 H -70.1 -42.0 NA NA NA
VAL E:79 E:142 28.0 0.181 H -55.9 -47.6 NA NA NA
VAL F:79 F:142 18.0 0.116 H -59.7 -51.2 NA NA NA
VAL G:79 G:142 24.0 0.155 H -64.9 -39.6 NA NA NA
VAL H:79 H:142 19.0 0.123 H -62.2 -47.7 NA NA NA
VAL I:79 I:142 22.0 0.142 H -57.9 -42.7 NA NA NA
VAL J:79 J:142 21.0 0.135 H -62.6 -41.9 NA NA NA
VAL K:79 K:142 26.0 0.168 H -60.5 -41.3 NA NA NA
VAL L:79 L:142 15.0 0.097 H -64.9 -46.2 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 18.0 0.116 H -61.2 -40.7 18.0 0.116 0.0 HOH
 6.430
 CA
 O
VAL B:79 B:142 24.0 0.155 H -65.6 -35.4 24.0 0.155 0.0 HOH
 6.737
 CA
 O
VAL C:79 C:142 27.0 0.174 H -60.0 -39.9 NA NA NA
VAL D:79 D:142 15.0 0.097 H -76.8 -38.4 NA NA NA
VAL E:79 E:142 24.0 0.155 H -66.9 -37.8 NA NA NA
VAL F:79 F:142 10.0 0.065 H -60.0 -39.0 NA NA NA
VAL G:79 G:142 24.0 0.155 H -70.1 -39.4 NA NA NA
VAL H:79 H:142 11.0 0.071 H -62.9 -38.0 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 24.0 0.155 H -60.9 -45.0 24.0 0.155 0.0 SO4
C8E
HOH
 7.267
7.883
3.544
 N
C
O
 O3
O9
O
VAL B:79 B:142 30.0 0.194 H -60.0 -43.5 30.0 0.194 0.0 SO4
HOH
 5.590
6.151
 N
O
 O2
O
VAL C:79 C:142 16.0 0.103 H -64.9 -42.9 NA NA NA
VAL D:79 D:142 26.0 0.168 H -61.5 -46.2 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 VAL A:79 A:142 26.0 0.168 H -63.1 -43.9 26.0 0.168 0.0 HOH
 6.557
 N
 O
VAL B:79 B:142 24.0 0.155 H -60.8 -44.0 24.0 0.155 0.0 PGE
HOH
 6.086
6.204
 CG2
N
 O2
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 VAL A:307 B:1142 46.0 0.297 H -74.0 -31.7 46.0 0.297 0.0 HOH
 7.332
 O
 O
VAL B:307 D:1142 38.0 0.245 H -62.6 -32.1 NA NA NA
VAL C:307 C:1142 28.0 0.181 H -78.2 -35.5 28.0 0.181 0.0 HOH
 7.175
 CG1
 O
VAL D:307 A:1142 38.0 0.245 H -78.1 -34.8 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 VAL A:72 A:142 26.0 0.168 H -71.0 -30.8 26.0 0.168 0.0 SO4
 7.133
 O
 O1
VAL B:72 B:142 27.0 0.174 H -71.3 -33.5 27.0 0.174 0.0 HOH
 5.080
 CG2
 O
VAL C:72 C:142 28.0 0.181 H -74.6 -29.9 NA NA NA
VAL D:72 D:142 29.0 0.187 H -72.7 -32.7 NA NA NA
VAL E:72 E:142 28.0 0.181 H -72.5 -30.8 NA NA NA
VAL F:72 F:142 33.0 0.213 H -71.2 -30.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 VAL A:142 A:142 0.0 0.0 H -62.4 -39.0