Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541932 . C A CCDS4781.1:NM_001188.3:c.410cGt>cTt_NP_001179.1:p.137R>L Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 ARG A:122 A:137 19.0 0.084 H -66.5 -38.9 19.0 0.084 0.0 HOH
 2.919
 O
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 ARG A:122 A:137 17.0 0.076 H -64.9 -42.4 17.0 0.076 0.0 HOH
 2.719
 O
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 ARG A:119 A:137 20.0 0.089 H -60.1 -43.4 20.0 0.089 0.0 HOH
 2.724
 O
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 ARG A:120 A:137 8.0 0.036 H -56.9 -53.1 8.0 0.036 0.0
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 ARG A:117 A:137 5.0 0.022 H -68.1 -34.7 5.0 0.022 0.0 HOH
 2.724
 NE
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 ARG A:120 A:137 33.0 0.147 H -58.2 -39.2 33.0 0.147 0.0 HOH
 5.731
 NH2
 O
ARG B:120 B:137 29.0 0.129 H -58.2 -40.3 29.0 0.129 0.0
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 ARG A:115 A:137 19.0 0.084 H -64.8 -40.2 19.0 0.084 0.0 HOH
 7.221
 O
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 26.0 0.116 H -63.9 -38.0 26.0 0.116 0.0 TFA
GOL
HOH
 2.664
2.373
3.440
 NE
NH1
NH1
 OXT
HO3
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 24.0 0.107 H -68.4 -42.2 24.0 0.107 0.0 MPD
HOH
 4.097
2.925
 CB
NH2
 C4
O
ARG B:121 B:137 45.0 0.2 H -68.9 -42.3 45.0 0.2 0.0 HOH
 3.247
 CD
 O
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 17.0 0.076 H -65.6 -40.0 11.0 0.049 0.027 B:O43521:0.027
 HOH
 5.582
 O
 O
ARG C:121 C:137 17.0 0.076 H -65.2 -40.2 11.0 0.049 0.027 D:O43521:0.027
 EDO
HOH
 6.367
3.328
 NH1
NH2
 H21
O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 32.0 0.142 H -63.3 -41.7 24.0 0.107 0.035 B:O43521:0.036
 HOH
 2.845
 NH1
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 33.0 0.147 H -62.9 -39.9 27.0 0.12 0.027 B:O43521:0.027
 HOH
 2.838
 O
 O
ARG C:121 C:137 22.0 0.098 H -66.7 -37.7 14.0 0.062 0.036 D:O43521:0.036
 HOH
 2.819
 O
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:121 A:137 14.0 0.062 H -67.4 -38.9 10.0 0.044 0.018 B:O43521:0.018
 HOH
 2.938
 O
 O
ARG C:121 C:137 14.0 0.062 H -67.8 -38.1 10.0 0.044 0.018 D:O43521:0.018
 EDO
HOH
 8.011
2.846
 NH2
O
 H11
O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ARG A:117 A:137 25.0 0.111 H -64.0 -38.2 21.0 0.093 0.018 B:P55957:0.018
 HOH
 2.810
 NE
 O
ARG C:117 C:137 16.0 0.071 H -63.7 -37.9 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ARG A:117 A:137 27.0 0.12 H -68.0 -35.3 27.0 0.12 0.0 CU
 8.555
 NH1
 CU
ARG C:117 C:137 20.0 0.089 H -65.4 -32.1 NA NA NA
ARG E:117 E:137 25.0 0.111 H -66.4 -34.5 NA NA NA
ARG G:117 G:137 17.0 0.076 H -64.6 -34.2 NA NA NA
ARG I:117 I:137 41.0 0.182 H -67.4 -32.5 NA NA NA
ARG K:117 K:137 21.0 0.093 H -67.4 -31.2 NA NA NA
ARG M:117 M:137 17.0 0.076 H -63.1 -36.2 NA NA NA
ARG O:117 O:137 18.0 0.08 H -64.7 -37.2 NA NA NA
ARG Q:117 Q:137 27.0 0.12 H -67.0 -32.5 NA NA NA
ARG S:117 S:137 44.0 0.196 H -65.4 -37.1 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 ARG A:121 A:137 8.0 0.036 H -65.8 -34.8 8.0 0.036 0.0 HOH
 2.804
 O
 O
ARG B:121 B:137 9.0 0.04 H -73.7 -33.8 9.0 0.04 0.0 HOH
 2.819
 O
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 ARG A:115 A:137 13.0 0.058 H -66.7 -38.3 13.0 0.058 0.0 ZN
HOH
 3.982
2.892
 NH2
O
 ZN
O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 ARG A:73 A:137 82.0 0.364 H -68.1 -37.0 82.0 0.364 0.0
ARG B:73 B:137 59.0 0.262 H -69.6 -35.0 59.0 0.262 0.0
ARG C:73 C:137 52.0 0.231 H -62.7 -39.9 NA NA NA
ARG D:73 D:137 67.0 0.298 H -67.1 -37.4 NA NA NA
ARG E:73 E:137 43.0 0.191 H -75.5 -38.1 NA NA NA
ARG F:73 F:137 39.0 0.173 H -78.0 -39.1 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 44.0 0.196 H -68.2 -36.0 28.0 0.124 0.072 B:Q16611:0.071
 PEE
 3.589
 NH1
 O1P
ARG B:74 B:137 40.0 0.178 H -67.2 -35.7 29.0 0.129 0.049 A:Q16611:0.049
 PEE
 3.482
 NH1
 O1P
ARG C:74 C:137 52.0 0.231 H -64.9 -34.1 NA NA NA
ARG D:74 D:137 39.0 0.173 H -67.4 -36.2 NA NA NA
ARG E:74 E:137 42.0 0.187 H -68.2 -36.8 NA NA NA
ARG F:74 F:137 38.0 0.169 H -66.9 -37.5 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 48.0 0.213 H -65.9 -34.1 40.0 0.178 0.035 B:Q16611:0.036
 8SP
HOH
 4.176
4.631
 NH1
NH2
 O2P
O
ARG B:74 B:137 70.0 0.311 H -62.7 -31.2 59.0 0.262 0.049 A:Q16611:0.049
 8SP
8SP
 4.420
6.699
 NH1
N
 O2P
C7A
ARG C:74 C:137 50.0 0.222 H -66.7 -31.8 NA NA NA
ARG D:74 D:137 62.0 0.276 H -62.9 -30.4 NA NA NA
ARG E:74 E:137 41.0 0.182 H -66.4 -30.3 NA NA NA
ARG F:74 F:137 33.0 0.147 H -65.8 -31.7 NA NA NA
ARG G:74 G:137 50.0 0.222 H -62.9 -32.3 NA NA NA
ARG H:74 H:137 60.0 0.267 H -65.0 -29.1 NA NA NA
ARG I:74 I:137 48.0 0.213 H -69.7 -26.4 NA NA NA
ARG J:74 J:137 62.0 0.276 H -64.8 -32.3 NA NA NA
ARG K:74 K:137 50.0 0.222 H -69.9 -26.3 NA NA NA
ARG L:74 L:137 41.0 0.182 H -62.7 -39.2 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 50.0 0.222 H -64.3 -38.8 44.0 0.196 0.026 B:Q16611:0.027
 SO4
EDO
HOH
 3.150
7.797
3.856
 NH2
N
NH2
 O1
O1
O
ARG B:74 B:137 47.0 0.209 H -63.1 -36.4 38.0 0.169 0.04 A:Q16611:0.04
 LMT
LMT
SO4
EDO
HOH
 2.852
6.361
2.565
8.071
2.707
 NH1
N
NH1
N
O
 O6B
C11
O3
O2
O
ARG C:74 C:137 48.0 0.213 H -63.2 -36.0 NA NA NA
ARG D:74 D:137 39.0 0.173 H -67.2 -31.2 NA NA NA
ARG E:74 E:137 32.0 0.142 H -59.5 -41.1 NA NA NA
ARG F:74 F:137 37.0 0.164 H -61.9 -37.7 NA NA NA
ARG G:74 G:137 54.0 0.24 H -59.1 -39.4 NA NA NA
ARG H:74 H:137 37.0 0.164 H -63.8 -35.5 NA NA NA
ARG I:74 I:137 36.0 0.16 H -67.8 -37.8 NA NA NA
ARG J:74 J:137 36.0 0.16 H -62.9 -36.0 NA NA NA
ARG K:74 K:137 43.0 0.191 H -68.0 -41.9 NA NA NA
ARG L:74 L:137 33.0 0.147 H -66.0 -40.0 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 43.0 0.191 H -66.5 -43.4 40.0 0.178 0.013 B:Q16611:0.013
 PG8
HOH
 7.087
5.687
 N
NH1
 C13
O
ARG B:74 B:137 57.0 0.253 H -67.5 -36.6 51.0 0.227 0.026 A:Q16611:0.027
 HOH
 9.409
 O
 O
ARG C:74 C:137 47.0 0.209 H -56.3 -31.7 NA NA NA
ARG D:74 D:137 30.0 0.133 H -64.8 -35.5 NA NA NA
ARG E:74 E:137 42.0 0.187 H -61.2 -41.7 NA NA NA
ARG F:74 F:137 39.0 0.173 H -60.9 -29.1 NA NA NA
ARG G:74 G:137 38.0 0.169 H -70.6 -27.8 NA NA NA
ARG H:74 H:137 27.0 0.12 H -62.0 -28.6 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 40.0 0.178 H -63.0 -34.4 38.0 0.169 0.009 B:Q16611:0.009
 SO4
C8E
C8E
LBN
HOH
 4.319
9.279
6.255
6.208
2.771
 NH1
N
N
NH2
O
 O2
C4
C2
C12
O
ARG B:74 B:137 24.0 0.107 H -67.7 -34.4 13.0 0.058 0.049 A:Q16611:0.049
 C8E
SO4
C8E
HOH
 4.051
2.938
8.957
3.444
 CD
NH1
NE
NH1
 C16
O4
O21
O
ARG C:74 C:137 37.0 0.164 H -63.4 -32.0 NA NA NA
ARG D:74 D:137 24.0 0.107 H -66.9 -32.8 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:74 A:137 52.0 0.231 H -64.2 -37.4 46.0 0.204 0.027 B:Q16611:0.027
 K6G
PGE
HOH
 7.127
9.775
2.449
 N
N
NH2
 C6
O4
O
ARG B:74 B:137 42.0 0.187 H -66.4 -34.0 39.0 0.173 0.014 A:Q16611:0.013
 K6G
PGE
PGE
HOH
 7.446
3.576
6.269
2.679
 N
NH1
N
O
 C4
O2
O4
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 ARG A:302 B:1137 39.0 0.173 H -63.9 -33.2 22.0 0.098 0.075 C:P42212+Q16611:0.076
 HOH
 2.671
 NH2
 O
ARG B:302 D:1137 50.0 0.222 H -62.2 -33.2 NA NA NA
ARG C:302 C:1137 56.0 0.249 H -63.1 -32.5 30.0 0.133 0.116 A:P42212+Q16611:0.116
 HOH
 7.373
 NH2
 O
ARG D:302 A:1137 62.0 0.276 H -62.3 -34.5 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 ARG A:67 A:137 68.0 0.302 H -69.0 -34.7 58.0 0.258 0.044 B:Q16611:0.044
 EPE
HOH
 2.705
7.384
 NH1
N
 O3S
O
ARG B:67 B:137 58.0 0.258 H -64.0 -28.4 55.0 0.244 0.014 A:Q16611:0.013
 EPE
SO4
HOH
 5.261
7.039
7.583
 NH2
N
N
 O3S
O2
O
ARG C:67 C:137 50.0 0.222 H -70.6 -35.6 NA NA NA
ARG D:67 D:137 54.0 0.24 H -74.0 -30.3 NA NA NA
ARG E:67 E:137 44.0 0.196 H -70.5 -26.2 NA NA NA
ARG F:67 F:137 18.0 NA H -70.6 -29.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 ARG A:137 A:137 11.0 0.049 H -60.5 -39.9