Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541939 . C A CCDS4781.1:NM_001188.3:c.403Ggc>Tgc_NP_001179.1:p.135G>C Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 GLY A:120 A:135 0.0 0.0 H -52.8 -47.7 0.0 0.0 0.0 HOH
 6.500
 N
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 GLY A:120 A:135 0.0 0.0 H -50.3 -49.4 0.0 0.0 0.0 HOH
 6.416
 N
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 GLY A:117 A:135 0.0 0.0 H -61.8 -39.4 0.0 0.0 0.0 HOH
 6.504
 N
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 GLY A:118 A:135 0.0 0.0 H -57.5 -54.1 0.0 0.0 0.0
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 GLY A:115 A:135 0.0 0.0 H -60.5 -42.3 0.0 0.0 0.0 HOH
 6.434
 N
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 GLY A:118 A:135 7.0 0.093 H -56.3 -43.8 0.0 0.0 0.093 B:Q16611:0.093
GLY B:118 B:135 7.0 0.093 H -56.4 -43.2 0.0 0.0 0.093 A:Q16611:0.093
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 GLY A:113 A:135 0.0 0.0 H -54.7 -43.9 0.0 0.0 0.0 HOH
 6.704
 O
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 9.0 0.12 H -54.6 -45.1 9.0 0.12 0.0 TFA
GOL
HOH
 6.680
7.579
7.135
 N
O
O
 F1
H32
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 13.0 0.173 H -59.4 -40.0 1.0 0.013 0.16 B:Q16611:0.16
 MPD
HOH
 6.767
6.271
 N
N
 O4
O
GLY B:119 B:135 10.0 0.133 H -59.4 -39.4 0.0 0.0 0.133 A:Q16611:0.133
 HOH
 8.809
 O
 O
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 12.0 0.16 H -61.2 -35.2 0.0 0.0 0.16 C:Q16611:0.16
 HOH
 9.949
 O
 O
GLY C:119 C:135 13.0 0.173 H -60.7 -35.6 0.0 0.0 0.173 A:Q16611:0.173
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 10.0 0.133 H -58.9 -42.8 0.0 0.0 0.133 A:Q16611:0.133
 HOH
 6.996
 O
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 0.0 0.0 H -56.1 -44.1 0.0 0.0 0.0 HOH
 6.799
 O
 O
GLY C:119 C:135 0.0 0.0 H -56.1 -43.7 0.0 0.0 0.0 HOH
 6.853
 O
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLY A:119 A:135 0.0 0.0 H -56.1 -46.4 0.0 0.0 0.0 HOH
 6.644
 O
 O
GLY C:119 C:135 0.0 0.0 H -54.9 -47.3 0.0 0.0 0.0 HOH
 6.731
 O
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 GLY A:115 A:135 0.0 0.0 H -62.7 -39.4 0.0 0.0 0.0 HOH
 6.032
 N
 O
GLY C:115 C:135 0.0 0.0 H -61.2 -39.5 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 GLY A:115 A:135 0.0 0.0 H -59.2 -41.5 0.0 0.0 0.0
GLY C:115 C:135 0.0 0.0 H -59.2 -41.8 NA NA NA
GLY E:115 E:135 0.0 0.0 H -59.3 -41.8 NA NA NA
GLY G:115 G:135 0.0 0.0 H -59.2 -41.6 NA NA NA
GLY I:115 I:135 0.0 0.0 H -59.3 -41.7 NA NA NA
GLY K:115 K:135 0.0 0.0 H -59.4 -41.7 NA NA NA
GLY M:115 M:135 0.0 0.0 H -59.1 -41.8 NA NA NA
GLY O:115 O:135 0.0 0.0 H -59.0 -41.4 NA NA NA
GLY Q:115 Q:135 0.0 0.0 H -59.4 -42.0 NA NA NA
GLY S:115 S:135 0.0 0.0 H -59.0 -41.7 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 GLY A:119 A:135 0.0 0.0 H -61.5 -45.5 0.0 0.0 0.0 HOH
 6.495
 N
 O
GLY B:119 B:135 0.0 0.0 H -60.1 -44.4 0.0 0.0 0.0 HOH
 6.522
 N
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 GLY A:113 A:135 0.0 0.0 H -57.1 -42.7 0.0 0.0 0.0 HOH
 6.646
 N
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 GLY A:71 A:135 19.0 0.253 H -62.6 -33.7 19.0 0.253 0.0
GLY B:71 B:135 12.0 0.16 H -63.3 -36.2 12.0 0.16 0.0
GLY C:71 C:135 14.0 0.187 H -61.9 -36.1 NA NA NA
GLY D:71 D:135 19.0 0.253 H -62.3 -33.2 NA NA NA
GLY E:71 E:135 26.0 0.347 H -63.4 -30.5 NA NA NA
GLY F:71 F:135 25.0 0.333 H -62.9 -34.0 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 20.0 0.267 H -62.2 -36.6 20.0 0.267 0.0 PEE
 4.545
 O
 C42
GLY B:72 B:135 17.0 0.227 H -62.6 -36.7 17.0 0.227 0.0 PEE
 6.163
 C
 C17
GLY C:72 C:135 20.0 0.267 H -61.2 -37.1 NA NA NA
GLY D:72 D:135 18.0 0.24 H -62.5 -37.2 NA NA NA
GLY E:72 E:135 20.0 0.267 H -62.4 -34.9 NA NA NA
GLY F:72 F:135 17.0 0.227 H -62.2 -36.6 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 16.0 0.213 H -60.9 -38.3 16.0 0.213 0.0 8SP
 6.441
 C
 C6B
GLY B:72 B:135 0.0 0.0 H -65.7 -36.2 0.0 0.0 0.0 8SP
8SP
 6.360
3.543
 C
O
 C7B
C3A
GLY C:72 C:135 16.0 0.213 H -63.5 -35.7 NA NA NA
GLY D:72 D:135 15.0 0.2 H -61.5 -37.2 NA NA NA
GLY E:72 E:135 17.0 0.227 H -60.7 -33.3 NA NA NA
GLY F:72 F:135 0.0 0.0 H -61.6 -36.5 NA NA NA
GLY G:72 G:135 16.0 0.213 H -63.0 -36.2 NA NA NA
GLY H:72 H:135 0.0 0.0 H -60.2 -37.2 NA NA NA
GLY I:72 I:135 17.0 0.227 H -65.2 -32.9 NA NA NA
GLY J:72 J:135 0.0 0.0 H -58.9 -41.8 NA NA NA
GLY K:72 K:135 15.0 0.2 H -62.4 -36.5 NA NA NA
GLY L:72 L:135 0.0 0.0 H -63.8 -38.6 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 16.0 0.213 H -60.4 -38.6 16.0 0.213 0.0 EDO
HOH
 7.511
9.787
 O
O
 O1
O
GLY B:72 B:135 13.0 0.173 H -65.7 -36.3 13.0 0.173 0.0 LMT
LMT
EDO
EDO
EDO
HOH
 6.409
3.737
5.895
8.395
9.128
7.266
 C
O
O
CA
CA
O
 C7
C8
O2
O2
C1
O
GLY C:72 C:135 16.0 0.213 H -56.9 -40.0 NA NA NA
GLY D:72 D:135 13.0 0.173 H -61.5 -39.9 NA NA NA
GLY E:72 E:135 17.0 0.227 H -56.1 -41.9 NA NA NA
GLY F:72 F:135 16.0 0.213 H -64.6 -34.5 NA NA NA
GLY G:72 G:135 17.0 0.227 H -63.3 -36.3 NA NA NA
GLY H:72 H:135 15.0 0.2 H -58.4 -37.9 NA NA NA
GLY I:72 I:135 18.0 0.24 H -57.6 -41.0 NA NA NA
GLY J:72 J:135 15.0 0.2 H -66.9 -35.4 NA NA NA
GLY K:72 K:135 16.0 0.213 H -55.6 -38.5 NA NA NA
GLY L:72 L:135 15.0 0.2 H -61.0 -38.4 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 17.0 0.227 H -64.2 -29.6 17.0 0.227 0.0 PG8
 6.696
 C
 C13
GLY B:72 B:135 13.0 0.173 H -55.7 -39.0 13.0 0.173 0.0
GLY C:72 C:135 16.0 0.213 H -63.3 -40.2 NA NA NA
GLY D:72 D:135 17.0 0.227 H -62.6 -34.1 NA NA NA
GLY E:72 E:135 18.0 0.24 H -64.3 -34.6 NA NA NA
GLY F:72 F:135 18.0 0.24 H -60.2 -36.0 NA NA NA
GLY G:72 G:135 21.0 0.28 H -66.5 -35.6 NA NA NA
GLY H:72 H:135 20.0 0.267 H -68.7 -36.1 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 16.0 0.213 H -63.4 -40.2 16.0 0.213 0.0 C8E
C8E
LBN
HOH
 8.745
3.698
6.402
7.673
 C
C
C
O
 C2
C2
C40
O
GLY B:72 B:135 16.0 0.213 H -61.1 -43.0 16.0 0.213 0.0 C8E
C8E
HOH
 6.431
9.136
9.965
 C
CA
C
 C1
C1
O
GLY C:72 C:135 16.0 0.213 H -60.7 -38.0 NA NA NA
GLY D:72 D:135 15.0 0.2 H -61.7 -37.7 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLY A:72 A:135 16.0 0.213 H -64.5 -38.3 16.0 0.213 0.0 K6G
PGE
HOH
 6.407
9.581
7.749
 C
C
O
 C5
O4
O
GLY B:72 B:135 15.0 0.2 H -63.7 -35.5 15.0 0.2 0.0 K6G
PG4
PGE
PGE
HOH
 6.730
9.169
9.956
3.335
7.479
 C
CA
CA
O
O
 C3
O3
O4
C4
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 GLY A:300 B:1135 19.0 0.253 H -57.8 -42.7 19.0 0.253 0.0 HOH
 8.574
 N
 O
GLY B:300 D:1135 19.0 0.253 H -57.0 -41.1 NA NA NA
GLY C:300 C:1135 18.0 0.24 H -57.9 -42.3 18.0 0.24 0.0
GLY D:300 A:1135 18.0 0.24 H -56.6 -43.3 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 GLY A:65 A:135 17.0 0.227 H -61.6 -39.5 17.0 0.227 0.0 EPE
HOH
 7.616
6.497
 C
O
 O1S
O
GLY B:65 B:135 16.0 0.213 H -62.0 -38.1 16.0 0.213 0.0 EPE
SO4
HOH
 8.173
5.889
4.620
 C
C
CA
 O3S
O1
O
GLY C:65 C:135 16.0 0.213 H -61.0 -38.4 NA NA NA
GLY D:65 D:135 17.0 0.227 H -60.8 -37.3 NA NA NA
GLY E:65 E:135 17.0 0.227 H -61.1 -37.5 NA NA NA
GLY F:65 F:135 15.0 0.2 H -62.2 -38.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 GLY A:135 A:135 0.0 0.0 H -57.2 -47.7