Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541940 . G A CCDS4781.1:NM_001188.3:c.402ttC>ttT_NP_001179.1:p.134F>F Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 PHE A:119 A:134 2.0 0.01 H -67.4 -44.1 2.0 0.01 0.0 HOH
 4.080
 N
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 PHE A:119 A:134 0.0 0.0 H -67.7 -47.6 0.0 0.0 0.0 HOH
 3.989
 N
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 PHE A:116 A:134 2.0 0.01 H -67.0 -40.2 2.0 0.01 0.0 HOH
 4.228
 N
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 PHE A:117 A:134 6.0 0.029 H -78.7 -23.2 4.0 0.019 0.01 B:None:0.01
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 PHE A:114 A:134 11.0 0.052 H -62.2 -46.1 2.0 0.01 0.042 B:P55957:0.043
 HOH
 3.596
 N
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 PHE A:117 A:134 3.0 0.014 H -65.6 -45.6 3.0 0.014 0.0
PHE B:117 B:134 2.0 0.01 H -65.4 -46.0 2.0 0.01 0.0 HOH
 7.020
 CD1
 O
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 PHE A:112 A:134 3.0 0.014 H -72.3 -40.4 3.0 0.014 0.0 HOH
 9.204
 CE2
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 24.0 0.114 H -67.3 -41.1 0.0 0.0 0.114 B:O43521:0.114
 TFA
GOL
HOH
 4.048
6.686
5.713
 N
O
N
 F1
H32
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 31.0 0.148 H -72.0 -43.6 6.0 0.029 0.119 C:O43521:0.119
 MPD
HOH
 4.435
4.649
 N
N
 C1
O
PHE B:118 B:134 36.0 0.171 H -71.0 -43.7 9.0 0.043 0.128 D:O43521:0.129
 HOH
 8.304
 O
 O
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 22.0 0.105 H -61.2 -44.0 3.0 0.014 0.091 B:O43521:0.09
 HOH
 8.552
 N
 O
PHE C:118 C:134 23.0 0.11 H -61.4 -43.8 3.0 0.014 0.096 D:O43521:0.095
 HOH
 8.314
 N
 O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 22.0 0.105 H -61.7 -42.3 0.0 0.0 0.105 B:O43521:0.105
 HOH
 5.491
 N
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 21.0 0.1 H -62.5 -42.1 1.0 0.005 0.095 B:O43521:0.095
 HOH
 5.773
 N
 O
PHE C:118 C:134 22.0 0.105 H -66.4 -42.5 2.0 0.01 0.095 D:O43521:0.095
 HOH
 5.511
 N
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 PHE A:118 A:134 28.0 0.133 H -63.7 -43.5 3.0 0.014 0.119 B:O43521:0.119
 HOH
 7.035
 O
 O
PHE C:118 C:134 28.0 0.133 H -63.6 -41.3 3.0 0.014 0.119 D:O43521:0.119
 HOH
 6.978
 O
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 PHE A:114 A:134 23.0 0.11 H -66.8 -38.5 2.0 0.01 0.1 B:P55957:0.1
 HOH
 3.219
 N
 O
PHE C:114 C:134 23.0 0.11 H -67.7 -37.1 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 PHE A:114 A:134 7.0 0.033 H -61.1 -48.2 0.0 0.0 0.033 B:Q16611:0.033
PHE C:114 C:134 7.0 0.033 H -61.0 -48.2 NA NA NA
PHE E:114 E:134 6.0 0.029 H -61.4 -48.4 NA NA NA
PHE G:114 G:134 8.0 0.038 H -61.5 -48.6 NA NA NA
PHE I:114 I:134 7.0 0.033 H -61.6 -48.1 NA NA NA
PHE K:114 K:134 7.0 0.033 H -61.3 -48.4 NA NA NA
PHE M:114 M:134 7.0 0.033 H -61.3 -48.1 NA NA NA
PHE O:114 O:134 9.0 0.043 H -61.3 -47.9 NA NA NA
PHE Q:114 Q:134 9.0 0.043 H -61.6 -48.2 NA NA NA
PHE S:114 S:134 6.0 0.029 H -61.2 -47.9 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 PHE A:118 A:134 1.0 0.005 H -61.8 -40.3 1.0 0.005 0.0 HOH
 4.133
 N
 O
PHE B:118 B:134 1.0 0.005 H -61.4 -41.8 1.0 0.005 0.0 HOH
 4.070
 N
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 PHE A:112 A:134 0.0 0.0 H -62.8 -45.5 0.0 0.0 0.0 HOH
 4.167
 N
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 PHE A:70 A:134 20.0 0.095 H -65.8 -44.0 0.0 0.0 0.095 B:Q16611:0.095
PHE B:70 B:134 11.0 0.052 H -68.6 -43.3 0.0 0.0 0.052 A:Q16611:0.052
PHE C:70 C:134 13.0 0.062 H -65.4 -42.5 NA NA NA
PHE D:70 D:134 7.0 0.033 H -64.7 -43.9 NA NA NA
PHE E:70 E:134 18.0 0.086 H -70.0 -49.5 NA NA NA
PHE F:70 F:134 32.0 0.152 H -67.1 -48.7 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 11.0 0.052 H -61.2 -45.8 0.0 0.0 0.052 B:Q16611:0.052
 PEE
 7.765
 O
 C42
PHE B:71 B:134 12.0 0.057 H -61.6 -45.6 1.0 0.005 0.052 A:Q16611:0.052
 PEE
 7.625
 N
 C16
PHE C:71 C:134 13.0 0.062 H -59.1 -50.7 NA NA NA
PHE D:71 D:134 12.0 0.057 H -61.4 -43.2 NA NA NA
PHE E:71 E:134 15.0 0.071 H -61.4 -46.2 NA NA NA
PHE F:71 F:134 11.0 0.052 H -62.2 -44.8 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 11.0 0.052 H -71.9 -40.0 0.0 0.0 0.052 B:Q16611:0.052
 8SP
HOH
 6.402
9.206
 N
O
 C6B
O
PHE B:71 B:134 14.0 0.067 H -70.4 -37.8 0.0 0.0 0.067 A:Q16611:0.067
 8SP
8SP
 6.617
6.017
 N
O
 C7B
C3A
PHE C:71 C:134 12.0 0.057 H -66.7 -40.8 NA NA NA
PHE D:71 D:134 6.0 0.029 H -68.4 -39.0 NA NA NA
PHE E:71 E:134 11.0 0.052 H -66.0 -44.5 NA NA NA
PHE F:71 F:134 11.0 0.052 H -67.7 -42.6 NA NA NA
PHE G:71 G:134 11.0 0.052 H -69.6 -39.6 NA NA NA
PHE H:71 H:134 12.0 0.057 H -72.4 -41.3 NA NA NA
PHE I:71 I:134 12.0 0.057 H -68.5 -39.7 NA NA NA
PHE J:71 J:134 11.0 0.052 H -69.2 -41.0 NA NA NA
PHE K:71 K:134 14.0 0.067 H -67.2 -43.9 NA NA NA
PHE L:71 L:134 9.0 0.043 H -68.4 -39.8 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 10.0 0.048 H -65.7 -41.1 0.0 0.0 0.048 B:Q16611:0.048
 SO4
HOH
 9.472
8.713
 CE1
CE1
 O1
O
PHE B:71 B:134 6.0 0.029 H -63.1 -38.7 0.0 0.0 0.029 A:Q16611:0.029
 LMT
LMT
SO4
EDO
HOH
 6.456
6.290
8.952
9.366
6.703
 N
C
O
O
O
 C7
C8
O3
O2
O
PHE C:71 C:134 10.0 0.048 H -67.2 -42.9 NA NA NA
PHE D:71 D:134 8.0 0.038 H -63.7 -41.9 NA NA NA
PHE E:71 E:134 10.0 0.048 H -66.4 -43.4 NA NA NA
PHE F:71 F:134 14.0 0.067 H -61.2 -42.9 NA NA NA
PHE G:71 G:134 8.0 0.038 H -67.1 -40.9 NA NA NA
PHE H:71 H:134 13.0 0.062 H -65.1 -43.6 NA NA NA
PHE I:71 I:134 11.0 0.052 H -65.4 -43.0 NA NA NA
PHE J:71 J:134 11.0 0.052 H -63.8 -39.8 NA NA NA
PHE K:71 K:134 9.0 0.043 H -68.1 -43.6 NA NA NA
PHE L:71 L:134 11.0 0.052 H -67.8 -40.4 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 15.0 0.071 H -66.7 -40.3 0.0 0.0 0.071 B:Q16611:0.071
 PG8
 7.055
 N
 C13
PHE B:71 B:134 10.0 0.048 H -78.4 -43.5 0.0 0.0 0.048 A:Q16611:0.048
PHE C:71 C:134 12.0 0.057 H -66.4 -40.5 NA NA NA
PHE D:71 D:134 9.0 0.043 H -66.1 -34.6 NA NA NA
PHE E:71 E:134 13.0 0.062 H -70.0 -37.7 NA NA NA
PHE F:71 F:134 9.0 0.043 H -63.7 -44.5 NA NA NA
PHE G:71 G:134 18.0 0.086 H -66.5 -35.4 NA NA NA
PHE H:71 H:134 12.0 0.057 H -69.5 -28.2 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 9.0 0.043 H -62.4 -41.5 0.0 0.0 0.043 B:Q16611:0.043
 C8E
LBN
HOH
 6.292
7.022
6.008
 C
N
CZ
 C1
C40
O
PHE B:71 B:134 9.0 0.043 H -64.6 -39.7 0.0 0.0 0.043 A:Q16611:0.043
 C8E
SO4
HOH
 6.559
9.018
7.780
 N
CE1
CZ
 C3
O4
O
PHE C:71 C:134 9.0 0.043 H -67.7 -41.5 NA NA NA
PHE D:71 D:134 13.0 0.062 H -68.0 -40.1 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 PHE A:71 A:134 14.0 0.067 H -62.2 -40.1 0.0 0.0 0.067 B:Q16611:0.067
 K6G
HOH
 7.037
6.542
 N
CZ
 C6
O
PHE B:71 B:134 13.0 0.062 H -60.6 -44.8 0.0 0.0 0.062 A:Q16611:0.062
 K6G
PGE
HOH
 7.314
6.271
6.349
 N
O
CE1
 C4
C4
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 PHE A:299 B:1134 16.0 0.076 H -62.4 -45.6 1.0 0.005 0.071 C:P42212+Q16611:0.071
 HOH
 6.800
 CE1
 O
PHE B:299 D:1134 18.0 0.086 H -63.4 -49.6 NA NA NA
PHE C:299 C:1134 14.0 0.067 H -67.5 -45.2 0.0 0.0 0.067 A:P42212+Q16611:0.067
PHE D:299 A:1134 14.0 0.067 H -64.6 -47.5 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 PHE A:64 A:134 13.0 0.062 H -63.2 -44.2 0.0 0.0 0.062 B:Q16611:0.062
 EPE
HOH
 8.578
7.317
 N
N
 O1S
O
PHE B:64 B:134 10.0 0.048 H -61.6 -44.4 0.0 0.0 0.048 A:Q16611:0.048
 EPE
SO4
HOH
 8.485
6.848
6.717
 N
N
C
 O3S
O1
O
PHE C:64 C:134 13.0 0.062 H -61.3 -45.0 NA NA NA
PHE D:64 D:134 10.0 0.048 H -61.7 -44.0 NA NA NA
PHE E:64 E:134 7.0 0.033 H -62.4 -44.4 NA NA NA
PHE F:64 F:134 14.0 0.067 H -61.6 -46.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 PHE A:134 A:134 3.0 0.014 H -64.4 -42.1