Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541953 . G A CCDS4781.1:NM_001188.3:c.389gCt>gTt_NP_001179.1:p.130A>V Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 ALA A:115 A:130 0.0 0.0 H -55.7 -40.1 0.0 0.0 0.0 HOH
 3.585
 N
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 ALA A:115 A:130 0.0 0.0 H -61.1 -42.7 0.0 0.0 0.0 HOH
 3.669
 N
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 ALA A:112 A:130 4.0 0.035 H -55.0 -41.8 4.0 0.035 0.0 HOH
 3.915
 CA
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 ALA A:113 A:130 33.0 0.287 H -57.4 -45.1 1.0 0.009 0.278 B:None:0.278
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 ALA A:110 A:130 50.0 0.435 H -60.1 -36.1 6.0 0.052 0.383 B:P55957:0.383
 HOH
 3.069
 O
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 ALA A:113 A:130 1.0 0.009 H -61.0 -36.3 1.0 0.009 0.0 HOH
 8.684
 CB
 O
ALA B:113 B:130 0.0 0.0 H -61.2 -36.4 0.0 0.0 0.0 HOH
 8.200
 CB
 O
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 ALA A:108 A:130 1.0 0.009 H -72.3 -28.1 1.0 0.009 0.0 HOH
 9.720
 CB
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 52.0 0.452 H -63.9 -33.2 11.0 0.096 0.356 B:O43521:0.357
 TFA
HOH
 3.781
3.822
 CA
CA
 F3
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 52.0 0.452 H -61.8 -36.2 11.0 0.096 0.356 C:O43521:0.357
 MPD
HOH
 3.992
6.730
 O
O
 C1
O
ALA B:114 B:130 52.0 0.452 H -60.1 -33.9 19.0 0.165 0.287 D:O43521:0.287
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 48.0 0.417 H -61.9 -37.0 0.0 0.0 0.417 B:O43521:0.417
 HOH
 5.781
 N
 O
ALA C:114 C:130 48.0 0.417 H -61.8 -37.3 0.0 0.0 0.417 D:O43521:0.417
 HOH
 5.755
 N
 O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 48.0 0.417 H -62.8 -33.1 2.0 0.017 0.4 B:O43521:0.4
 HOH
 3.398
 CA
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 51.0 0.443 H -60.8 -34.6 0.0 0.0 0.443 B:O43521:0.443
 HOH
 3.748
 CA
 O
ALA C:114 C:130 46.0 0.4 H -63.7 -32.0 2.0 0.017 0.383 D:O43521:0.383
 HOH
 3.166
 CA
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ALA A:114 A:130 50.0 0.435 H -59.2 -35.4 0.0 0.0 0.435 B:O43521:0.435
 HOH
 3.641
 N
 O
ALA C:114 C:130 49.0 0.426 H -58.5 -34.7 0.0 0.0 0.426 D:O43521:0.426
 HOH
 3.505
 N
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ALA A:110 A:130 51.0 0.443 H -61.2 -35.1 2.0 0.017 0.426 B:P55957:0.426
 HOH
 2.565
 O
 O
ALA C:110 C:130 51.0 0.443 H -62.2 -36.7 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ALA A:110 A:130 41.0 0.357 H -62.7 -41.7 3.0 0.026 0.331 B:Q16611:0.33
ALA C:110 C:130 40.0 0.348 H -62.5 -41.0 NA NA NA
ALA E:110 E:130 41.0 0.357 H -62.5 -41.4 NA NA NA
ALA G:110 G:130 39.0 0.339 H -62.7 -41.5 NA NA NA
ALA I:110 I:130 43.0 0.374 H -62.6 -41.6 NA NA NA
ALA K:110 K:130 42.0 0.365 H -62.4 -41.5 NA NA NA
ALA M:110 M:130 43.0 0.374 H -62.2 -41.1 NA NA NA
ALA O:110 O:130 41.0 0.357 H -62.3 -41.0 NA NA NA
ALA Q:110 Q:130 39.0 0.339 H -62.3 -41.7 NA NA NA
ALA S:110 S:130 42.0 0.365 H -62.4 -41.1 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 ALA A:114 A:130 2.0 0.017 H -56.9 -35.5 2.0 0.017 0.0 HOH
 3.520
 CA
 O
ALA B:114 B:130 1.0 0.009 H -57.8 -37.1 1.0 0.009 0.0 HOH
 3.668
 CA
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 ALA A:108 A:130 23.0 0.2 H -64.6 -37.3 23.0 0.2 0.0 HOH
 5.149
 O
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 ALA A:66 A:130 51.0 0.443 H -62.8 -37.9 2.0 0.017 0.426 B:Q16611:0.426
ALA B:66 B:130 44.0 0.383 H -66.5 -38.8 1.0 0.009 0.374 A:Q16611:0.374
ALA C:66 C:130 45.0 0.391 H -66.5 -38.7 NA NA NA
ALA D:66 D:130 49.0 0.426 H -62.6 -39.6 NA NA NA
ALA E:66 E:130 68.0 0.591 H -59.6 -43.1 NA NA NA
ALA F:66 F:130 53.0 0.461 H -61.5 -42.2 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 44.0 0.383 H -61.1 -36.3 0.0 0.0 0.383 B:Q16611:0.383
 PEE
 8.791
 N
 C15
ALA B:67 B:130 45.0 0.391 H -61.6 -37.4 0.0 0.0 0.391 A:Q16611:0.391
 PEE
PEE
 9.856
8.745
 N
O
 C12
C16
ALA C:67 C:130 45.0 0.391 H -65.5 -41.0 NA NA NA
ALA D:67 D:130 43.0 0.374 H -61.4 -37.0 NA NA NA
ALA E:67 E:130 41.0 0.357 H -60.2 -36.2 NA NA NA
ALA F:67 F:130 46.0 0.4 H -60.9 -36.7 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 45.0 0.391 H -70.3 -37.3 0.0 0.0 0.391 B:Q16611:0.391
 8SP
8SP
HOH
 7.724
7.862
9.717
 N
O
CB
 C8B
C6B
O
ALA B:67 B:130 48.0 0.417 H -63.4 -42.4 0.0 0.0 0.417 A:Q16611:0.417
 8SP
8SP
8SP
 7.721
8.007
8.221
 N
N
O
 C8B
C5B
C7A
ALA C:67 C:130 47.0 0.409 H -65.1 -40.7 NA NA NA
ALA D:67 D:130 48.0 0.417 H -67.8 -41.6 NA NA NA
ALA E:67 E:130 46.0 0.4 H -65.4 -39.5 NA NA NA
ALA F:67 F:130 46.0 0.4 H -65.8 -39.7 NA NA NA
ALA G:67 G:130 48.0 0.417 H -65.0 -39.9 NA NA NA
ALA H:67 H:130 46.0 0.4 H -67.6 -39.5 NA NA NA
ALA I:67 I:130 47.0 0.409 H -65.0 -39.0 NA NA NA
ALA J:67 J:130 48.0 0.417 H -63.6 -38.9 NA NA NA
ALA K:67 K:130 46.0 0.4 H -69.0 -33.0 NA NA NA
ALA L:67 L:130 47.0 0.409 H -65.8 -40.1 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 47.0 0.409 H -58.9 -47.3 0.0 0.0 0.409 B:Q16611:0.409
 LMT
 7.857
 N
 C6
ALA B:67 B:130 49.0 0.426 H -65.0 -41.4 0.0 0.0 0.426 A:Q16611:0.426
 LMT
LMT
EDO
HOH
 7.665
8.565
9.636
9.251
 O
O
C
CB
 C7
C10
O1
O
ALA C:67 C:130 46.0 0.4 H -63.2 -39.5 NA NA NA
ALA D:67 D:130 50.0 0.435 H -62.3 -42.6 NA NA NA
ALA E:67 E:130 48.0 0.417 H -62.6 -41.7 NA NA NA
ALA F:67 F:130 47.0 0.409 H -62.3 -42.7 NA NA NA
ALA G:67 G:130 47.0 0.409 H -65.4 -42.2 NA NA NA
ALA H:67 H:130 49.0 0.426 H -61.4 -43.0 NA NA NA
ALA I:67 I:130 46.0 0.4 H -57.4 -43.8 NA NA NA
ALA J:67 J:130 50.0 0.435 H -64.4 -41.3 NA NA NA
ALA K:67 K:130 46.0 0.4 H -61.7 -43.4 NA NA NA
ALA L:67 L:130 50.0 0.435 H -65.8 -37.5 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 47.0 0.409 H -62.6 -44.4 1.0 0.009 0.4 B:Q16611:0.4
 PG8
 8.285
 O
 C14
ALA B:67 B:130 46.0 0.4 H -64.0 -41.5 1.0 0.009 0.391 A:Q16611:0.391
 PG8
 8.175
 N
 C13
ALA C:67 C:130 45.0 0.391 H -65.5 -33.8 NA NA NA
ALA D:67 D:130 49.0 0.426 H -66.8 -32.1 NA NA NA
ALA E:67 E:130 50.0 0.435 H -63.8 -39.4 NA NA NA
ALA F:67 F:130 44.0 0.383 H -63.6 -42.3 NA NA NA
ALA G:67 G:130 48.0 0.417 H -60.9 -33.4 NA NA NA
ALA H:67 H:130 47.0 0.409 H -59.9 -36.0 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 44.0 0.383 H -59.3 -43.7 1.0 0.009 0.374 B:Q16611:0.374
 C8E
C8E
LBN
HOH
 8.257
8.446
8.109
8.771
 O
N
O
CB
 C1
C2
C40
O
ALA B:67 B:130 48.0 0.417 H -60.8 -42.5 0.0 0.0 0.417 A:Q16611:0.417
 C8E
LBN
C8E
 8.077
8.387
8.768
 O
N
C
 C3
C40
C1
ALA C:67 C:130 45.0 0.391 H -59.6 -41.3 NA NA NA
ALA D:67 D:130 50.0 0.435 H -65.8 -38.7 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ALA A:67 A:130 48.0 0.417 H -59.8 -42.7 0.0 0.0 0.417 B:Q16611:0.417
 K6G
K6G
HOH
 8.283
8.330
8.959
 N
O
CB
 C4
C5
O
ALA B:67 B:130 46.0 0.4 H -59.6 -43.3 1.0 0.009 0.391 A:Q16611:0.391
 K6G
K6G
PG4
PGE
HOH
 8.631
8.534
8.867
8.555
9.328
 O
N
C
O
CB
 C4
C6
C5
C6
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 ALA A:295 B:1130 44.0 0.383 H -62.5 -42.0 1.0 0.009 0.374 C:P42212+Q16611:0.374
 HOH
 8.798
 O
 O
ALA B:295 D:1130 43.0 0.374 H -61.1 -42.9 NA NA NA
ALA C:295 C:1130 45.0 0.391 H -61.2 -37.8 1.0 0.009 0.382 A:P42212+Q16611:0.383
ALA D:295 A:1130 42.0 0.365 H -60.9 -43.4 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 ALA A:60 A:130 46.0 0.4 H -66.1 -39.5 0.0 0.0 0.4 B:Q16611:0.4
 EPE
SO4
HOH
 8.970
8.469
8.671
 N
N
O
 O3S
O4
O
ALA B:60 B:130 42.0 0.365 H -63.2 -37.9 0.0 0.0 0.365 A:Q16611:0.365
 EPE
SO4
HOH
 9.557
8.072
8.655
 N
O
O
 O3S
O1
O
ALA C:60 C:130 44.0 0.383 H -65.0 -40.5 NA NA NA
ALA D:60 D:130 44.0 0.383 H -63.2 -37.9 NA NA NA
ALA E:60 E:130 46.0 0.4 H -62.6 -38.9 NA NA NA
ALA F:60 F:130 47.0 0.409 H -62.8 -39.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 ALA A:130 A:130 5.0 0.043 H -62.1 -35.8