Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33541983 . T A CCDS4781.1:NM_001188.3:c.359gAg>gTg_NP_001179.1:p.120E>V Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 GLU A:105 A:120 168.0 0.884 T -55.4 -38.7 168.0 0.884 0.0 HOH
 2.824
 OE2
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 GLU A:105 A:120 160.0 0.842 T -53.6 -41.2 160.0 0.842 0.0 HOH
 2.760
 O
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 GLU A:102 A:120 143.0 0.753 S -51.8 -46.0 143.0 0.753 0.0 HOH
 3.529
 N
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 GLU A:103 A:120 142.0 0.747 T -50.0 -39.1 142.0 0.747 0.0
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 GLU A:100 A:120 147.0 0.774 H -61.9 -37.1 147.0 0.774 0.0 HOH
 3.371
 N
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 GLU A:103 A:120 154.0 0.811 T -54.1 -42.6 154.0 0.811 0.0 HOH
 3.858
 N
 O
GLU B:103 B:120 154.0 0.811 T -54.1 -42.6 154.0 0.811 0.0 HOH
 8.066
 N
 O
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 GLU A:98 A:120 137.0 0.721 T -46.5 -67.7 137.0 0.721 0.0
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 154.0 0.811 T -57.3 -32.9 138.0 0.726 0.085 B:O43521:0.084
 EDO
HOH
 7.515
2.816
 C
OE1
 HO1
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 159.0 0.837 T -61.9 -39.1 159.0 0.837 0.0 BR
HOH
 8.690
3.849
 C
CB
 BR
O
GLU B:104 B:120 143.0 0.753 T -62.7 -36.0 129.0 0.679 0.074 D:O43521:0.074
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 160.0 0.842 T -67.2 -35.9 154.0 0.811 0.031 B:O43521:0.032
 HOH
 9.683
 OE1
 O
GLU C:104 C:120 160.0 0.842 T -66.0 -36.4 150.0 0.789 0.053 D:O43521:0.053
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 145.0 0.763 T -59.3 -41.2 139.0 0.732 0.031 B:O43521:0.032
 HOH
 2.646
 OE2
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 156.0 0.821 T -55.5 -41.0 147.0 0.774 0.047 B:O43521:0.047
 HOH
 2.237
 OE1
 O
GLU C:104 C:120 162.0 0.853 H -57.6 -44.2 156.0 0.821 0.032 D:O43521:0.032
 HOH
 2.731
 O
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 GLU A:104 A:120 163.0 0.858 T -62.7 -29.4 155.0 0.816 0.042 B:O43521:0.042
 HOH
 2.439
 OE1
 O
GLU C:104 C:120 167.0 0.879 H -69.7 -28.0 167.0 0.879 0.0 HOH
 2.498
 O
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 GLU A:100 A:120 152.0 0.8 S -58.8 -40.6 152.0 0.8 0.0 HOH
 2.766
 OE2
 O
GLU C:100 C:120 86.0 NA T -59.5 -37.9 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 GLU A:100 A:120 150.0 0.789 T -65.1 -25.4 138.0 0.726 0.063 B:Q16611:0.063
GLU C:100 C:120 159.0 0.837 T -63.3 -29.3 NA NA NA
GLU E:100 E:120 164.0 0.863 T -65.4 -26.1 NA NA NA
GLU G:100 G:120 160.0 0.842 T -62.5 -31.7 NA NA NA
GLU I:100 I:120 152.0 0.8 T -64.5 -19.3 NA NA NA
GLU K:100 K:120 146.0 0.768 T -58.9 -41.2 NA NA NA
GLU M:100 M:120 163.0 0.858 T -61.4 -27.7 NA NA NA
GLU O:100 O:120 148.0 0.779 T -55.7 -43.3 NA NA NA
GLU Q:100 Q:120 155.0 0.816 T -73.9 -5.0 NA NA NA
GLU S:100 S:120 152.0 0.8 T -60.8 -31.7 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 GLU A:104 A:120 155.0 0.816 T -64.8 -29.5 155.0 0.816 0.0 HOH
 2.565
 OE2
 O
GLU B:104 B:120 157.0 0.826 T -67.8 -23.7 157.0 0.826 0.0 HOH
 2.573
 OE2
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 GLU A:98 A:120 171.0 0.9 T -59.3 -33.4 171.0 0.9 0.0 HOH
 3.250
 N
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 GLU A:56 A:120 158.0 0.832 H -64.4 -21.9 158.0 0.832 0.0
GLU B:56 B:120 154.0 0.811 H -65.5 -25.1 154.0 0.811 0.0
GLU C:56 C:120 152.0 0.8 H -66.5 -24.8 NA NA NA
GLU D:56 D:120 156.0 0.821 H -64.7 -22.5 NA NA NA
GLU E:56 E:120 158.0 0.832 H -69.9 -22.5 NA NA NA
GLU F:56 F:120 145.0 0.763 H -69.4 -30.7 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 163.0 0.858 H -69.3 -15.2 163.0 0.858 0.0 PEE
 9.829
 N
 C31
GLU B:57 B:120 166.0 0.874 H -69.0 -15.1 166.0 0.874 0.0
GLU C:57 C:120 163.0 0.858 T -72.6 -8.3 NA NA NA
GLU D:57 D:120 166.0 0.874 H -68.0 -14.4 NA NA NA
GLU E:57 E:120 162.0 0.853 H -68.9 -15.6 NA NA NA
GLU F:57 F:120 165.0 0.868 H -68.8 -15.7 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 164.0 0.863 T -65.0 -26.3 162.0 0.853 0.01 B:Q16611:0.011
 SO4
 7.230
 OE1
 O1
GLU B:57 B:120 165.0 0.868 T -69.7 -14.4 159.0 0.837 0.031 A:Q16611:0.032
 HOH
 4.402
 C
 O
GLU C:57 C:120 165.0 0.868 G -64.3 -29.6 NA NA NA
GLU D:57 D:120 155.0 0.816 T -68.6 -18.9 NA NA NA
GLU E:57 E:120 154.0 0.811 G -66.2 -26.3 NA NA NA
GLU F:57 F:120 168.0 0.884 T -65.7 -21.2 NA NA NA
GLU G:57 G:120 158.0 0.832 T -62.5 -31.5 NA NA NA
GLU H:57 H:120 160.0 0.842 T -65.3 -22.4 NA NA NA
GLU I:57 I:120 162.0 0.853 G -71.0 -24.7 NA NA NA
GLU J:57 J:120 152.0 0.8 T -65.5 -23.4 NA NA NA
GLU K:57 K:120 159.0 0.837 G -67.0 -27.1 NA NA NA
GLU L:57 L:120 160.0 0.842 T -64.7 -19.4 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 171.0 0.9 T -62.5 -25.3 163.0 0.858 0.042 B:Q16611:0.042
 SO4
HOH
 6.034
2.903
 OE1
OE1
 O2
O
GLU B:57 B:120 155.0 0.816 T -60.9 -19.3 149.0 0.784 0.032 A:Q16611:0.032
 SO4
EDO
HOH
 5.398
8.002
2.987
 OE1
N
OE1
 O4
O1
O
GLU C:57 C:120 160.0 0.842 T -57.9 -30.7 NA NA NA
GLU D:57 D:120 154.0 0.811 T -65.3 -11.4 NA NA NA
GLU E:57 E:120 163.0 0.858 T -55.5 -28.6 NA NA NA
GLU F:57 F:120 158.0 0.832 T -60.6 -20.8 NA NA NA
GLU G:57 G:120 161.0 0.847 T -55.6 -36.9 NA NA NA
GLU H:57 H:120 157.0 0.826 T -63.7 -16.2 NA NA NA
GLU I:57 I:120 158.0 0.832 T -61.0 -36.3 NA NA NA
GLU J:57 J:120 152.0 0.8 T -59.8 -18.5 NA NA NA
GLU K:57 K:120 166.0 0.874 T -55.3 -32.0 NA NA NA
GLU L:57 L:120 162.0 0.853 T -61.5 -19.7 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 154.0 0.811 T -67.0 -20.3 154.0 0.811 0.0
GLU B:57 B:120 151.0 0.795 T -63.5 -29.2 148.0 0.779 0.016 A:Q16611:0.016
GLU C:57 C:120 159.0 0.837 T -65.4 -17.9 NA NA NA
GLU D:57 D:120 147.0 0.774 T -55.2 -25.0 NA NA NA
GLU E:57 E:120 159.0 0.837 T -61.5 -25.1 NA NA NA
GLU F:57 F:120 161.0 0.847 T -70.4 -10.5 NA NA NA
GLU G:57 G:120 153.0 0.805 T -61.6 -22.1 NA NA NA
GLU H:57 H:120 157.0 0.826 T -61.7 -17.5 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 154.0 0.811 H -56.3 -39.5 154.0 0.811 0.0 C8E
EDO
C8E
EDO
HOH
 2.931
3.222
7.577
6.865
3.307
 O
O
O
CG
N
 O18
C2
C10
C1
O
GLU B:57 B:120 158.0 0.832 H -54.4 -37.5 145.0 0.763 0.069 A:Q16611:0.068
 C8E
HOH
 6.915
2.835
 N
OE2
 C8
O
GLU C:57 C:120 155.0 0.816 T -68.0 -23.2 NA NA NA
GLU D:57 D:120 153.0 0.805 H -70.8 -25.8 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 GLU A:57 A:120 163.0 0.858 T -67.0 -20.2 163.0 0.858 0.0 K6G
HOH
 9.056
4.202
 O
OE2
 O
O
GLU B:57 B:120 168.0 0.884 H -60.2 -32.0 163.0 0.858 0.026 A:Q16611:0.026
 PG4
PGE
HOH
 8.079
7.280
3.057
 N
N
OE1
 O1
O1
O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 GLU A:285 B:1120 162.0 0.853 T -69.3 -14.5 162.0 0.853 0.0 CAC
HOH
 3.339
3.010
 O
CG
 O1
O
GLU B:285 D:1120 153.0 0.805 T -69.5 -18.0 NA NA NA
GLU C:285 C:1120 159.0 0.837 T -67.2 -18.1 138.0 0.726 0.111 A:P42212+Q16611:0.111
 HOH
 2.777
 OE2
 O
GLU D:285 A:1120 147.0 0.774 T -69.6 -18.3 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 GLU A:50 A:120 153.0 0.805 H -61.5 -35.2 153.0 0.805 0.0
GLU B:50 B:120 162.0 0.853 T -76.3 -8.0 162.0 0.853 0.0
GLU C:50 C:120 150.0 0.789 H -67.6 -23.4 NA NA NA
GLU D:50 D:120 166.0 0.874 H -66.7 -33.4 NA NA NA
GLU E:50 E:120 176.0 0.926 H -57.0 -37.6 NA NA NA
GLU F:50 F:120 171.0 0.9 T -66.7 -9.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 GLU A:120 A:120 102.0 0.537 T -56.0 -45.2