Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr6 | 33543117 | . | G | A | CCDS4781.1:NM_001188.3:c.308aCg>aTg_NP_001179.1:p.103T>M | Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2ims | 1 | Q16611 | 100.0 | 2e-126 |
X-RAY |
2006-12-26 | THR | A:88 | A:103 | 66.0 | 0.471 | S | -122.2 | 160.3 | 27.0 | 0.193 | 0.278 |
A:Q16611:0.279 |
HOH |
2.851 |
OG1 |
O |
|
| 2imt | 1 | Q16611 | 100.0 | 2e-126 |
X-RAY |
2007-01-23 | THR | A:88 | A:103 | 60.0 | 0.429 | S | -122.2 | 160.3 | 24.0 | 0.171 | 0.258 |
A:Q16611:0.257 |
HOH |
2.539 |
OG1 |
O |
|
| 2jcn | 1 | Q16611 | 100.0 | 5e-126 |
X-RAY |
2007-01-04 | THR | A:85 | A:103 | 58.0 | 0.414 | -115.5 | 169.3 | 58.0 | 0.414 | 0.0 |
HOH |
2.665 |
OG1 |
O |
|||
| 2m5b | 1 | Q16611 | 100.0 | 8e-125 |
NMR |
2013-04-17 | THR | A:86 | A:103 | 48.0 | 0.343 | -138.9 | 171.4 | 48.0 | 0.343 | 0.0 | |||||||
| 7m5a | 1 | Q16611 | 99.4 | 2e-121 |
X-RAY |
2022-01-12 | THR | A:83 | A:103 | 52.0 | 0.371 | -134.7 | 174.7 | 52.0 | 0.371 | 0.0 |
HOH |
2.761 |
OG1 |
O |
|||
| 4u2u | 1 | Q16611 | 98.21 | 1e-120 |
X-RAY |
2014-09-10 | THR | A:86 | A:103 | 26.0 | 0.186 | -103.4 | 172.3 | 26.0 | 0.186 | 0.0 |
HOH |
4.191 |
N |
O |
|||
| THR | B:86 | B:103 | 26.0 | 0.186 | -120.7 | 168.0 | 26.0 | 0.186 | 0.0 |
HOH |
5.276 |
OG1 |
O |
||||||||||
| 2yv6 | 1 | Q16611 | 100.0 | 2e-120 |
X-RAY |
2008-04-15 | THR | A:81 | A:103 | 57.0 | 0.407 | -116.3 | 168.2 | 57.0 | 0.407 | 0.0 |
HOH |
3.672 |
C |
O |
|||
| 5vwv | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 43.0 | 0.307 | -137.9 | 166.8 | 43.0 | 0.307 | 0.0 |
EDO HOH |
6.551 2.679 |
O OG1 |
HO2 O |
|||
| 5vww | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 62.0 | 0.443 | -109.4 | 169.1 | 62.0 | 0.443 | 0.0 |
HOH |
8.403 |
OG1 |
O |
|||
| THR | B:87 | B:103 | 63.0 | 0.45 | -109.5 | 167.4 | 63.0 | 0.45 | 0.0 |
HOH |
3.631 |
CA |
O |
||||||||||
| 5vwx | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 31.0 | 0.221 | -116.8 | 171.7 | 31.0 | 0.221 | 0.0 |
HOH |
8.373 |
CG2 |
O |
|||
| THR | C:87 | C:103 | 31.0 | 0.221 | -117.3 | 173.0 | 31.0 | 0.221 | 0.0 |
HOH |
8.532 |
CG2 |
O |
||||||||||
| 5vwy | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 39.0 | 0.279 | -131.5 | 170.8 | 39.0 | 0.279 | 0.0 |
HOH |
2.582 |
OG1 |
O |
|||
| 5vwz | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 53.0 | 0.379 | -134.6 | 169.1 | 53.0 | 0.379 | 0.0 |
HOH |
2.732 |
OG1 |
O |
|||
| THR | C:87 | C:103 | 57.0 | 0.407 | -136.2 | 174.1 | 57.0 | 0.407 | 0.0 |
HOH |
3.701 |
CA |
O |
||||||||||
| 5vx0 | 1 | Q16611 | 98.21 | 2e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 57.0 | 0.407 | -130.7 | 173.7 | 57.0 | 0.407 | 0.0 |
MG MG HOH |
3.524 8.055 2.789 |
CB C OG1 |
MG MG O |
|||
| THR | C:87 | C:103 | 65.0 | 0.464 | -127.7 | 173.5 | 65.0 | 0.464 | 0.0 |
MG HOH |
8.190 2.781 |
C OG1 |
MG O |
||||||||||
| 7m5b | 1 | Q16611 | 98.8 | 4e-120 |
X-RAY |
2022-01-12 | THR | A:83 | A:103 | 54.0 | 0.386 | -133.3 | 174.1 | 54.0 | 0.386 | 0.0 |
HOH |
2.649 |
OG1 |
O |
|||
| THR | C:83 | C:103 | 63.0 | 0.45 | -138.8 | 171.0 | NA | NA | NA | ||||||||||||||
| 7m5c | 1 | Q16611 | 98.8 | 4e-120 |
X-RAY |
2022-01-12 | THR | A:83 | A:103 | 76.0 | 0.543 | T | -86.5 | -20.4 | 76.0 | 0.543 | 0.0 |
CU SO4 |
8.135 6.892 |
N O |
CU O2 |
||
| THR | C:83 | C:103 | 78.0 | 0.557 | T | -84.6 | -20.8 | NA | NA | NA | |||||||||||||
| THR | E:83 | E:103 | 69.0 | 0.493 | S | -87.9 | -159.3 | NA | NA | NA | |||||||||||||
| THR | G:83 | G:103 | 85.0 | 0.607 | T | -85.9 | -20.3 | NA | NA | NA | |||||||||||||
| THR | I:83 | I:103 | 90.0 | 0.643 | S | -109.9 | -22.0 | NA | NA | NA | |||||||||||||
| THR | K:83 | K:103 | 86.0 | 0.614 | T | -86.7 | -21.0 | NA | NA | NA | |||||||||||||
| THR | M:83 | M:103 | 95.0 | 0.679 | T | -84.9 | -20.5 | NA | NA | NA | |||||||||||||
| THR | O:83 | O:103 | 91.0 | 0.65 | T | -85.6 | -21.3 | NA | NA | NA | |||||||||||||
| THR | Q:83 | Q:103 | 97.0 | 0.693 | T | -86.5 | -20.4 | NA | NA | NA | |||||||||||||
| THR | S:83 | S:103 | 98.0 | NA | T | -82.4 | -3.9 | NA | NA | NA | |||||||||||||
| 5vx1 | 1 | Q16611 | 97.62 | 9e-120 |
X-RAY |
2017-11-15 | THR | A:87 | A:103 | 65.0 | 0.464 | -119.9 | 173.4 | 65.0 | 0.464 | 0.0 |
HOH |
2.669 |
OG1 |
O |
|||
| THR | B:87 | B:103 | 36.0 | 0.257 | -118.7 | 173.3 | 36.0 | 0.257 | 0.0 |
HOH |
2.805 |
OG1 |
O |
||||||||||
| 5fmi | 1 | Q16611 | 98.77 | 3e-117 |
X-RAY |
2016-06-01 | THR | A:81 | A:103 | 69.0 | 0.493 | S | -88.9 | 169.1 | 34.0 | 0.243 | 0.25 |
A:Q16611:0.25 |
HOH |
2.679 |
OG1 |
O |
|
| 7k02 | 1 | Q16611 | 99.17 | 2e-85 |
X-RAY |
2021-03-31 | THR | A:39 | A:103 | 46.0 | 0.329 | -161.1 | 164.1 | 46.0 | 0.329 | 0.0 | |||||||
| THR | B:39 | B:103 | 61.0 | 0.436 | -150.6 | 162.3 | 61.0 | 0.436 | 0.0 | ||||||||||||||
| THR | C:39 | C:103 | 57.0 | 0.407 | -120.2 | 162.3 | NA | NA | NA | ||||||||||||||
| THR | D:39 | D:103 | 47.0 | 0.336 | -121.1 | 163.9 | NA | NA | NA | ||||||||||||||
| THR | E:39 | E:103 | 65.0 | 0.464 | -117.3 | 142.8 | NA | NA | NA | ||||||||||||||
| THR | F:39 | F:103 | 61.0 | 0.436 | -114.0 | 138.9 | NA | NA | NA | ||||||||||||||
| 6uxm | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 63.0 | 0.45 | -123.8 | 175.3 | 63.0 | 0.45 | 0.0 | |||||||
| THR | B:40 | B:103 | 50.0 | 0.357 | -125.3 | 176.1 | 50.0 | 0.357 | 0.0 | ||||||||||||||
| THR | C:40 | C:103 | 64.0 | 0.457 | -133.8 | 176.4 | NA | NA | NA | ||||||||||||||
| THR | D:40 | D:103 | 61.0 | 0.436 | -123.6 | 176.3 | NA | NA | NA | ||||||||||||||
| THR | E:40 | E:103 | 63.0 | 0.45 | -123.2 | 175.7 | NA | NA | NA | ||||||||||||||
| THR | F:40 | F:103 | 51.0 | 0.364 | -125.2 | 175.2 | NA | NA | NA | ||||||||||||||
| 6uxn | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 70.0 | 0.5 | -121.1 | 175.1 | 70.0 | 0.5 | 0.0 |
HOH |
5.866 |
O |
O |
|||
| THR | B:40 | B:103 | 56.0 | 0.4 | -129.2 | 176.1 | 56.0 | 0.4 | 0.0 |
8SP HOH |
4.499 3.992 |
O C |
N O |
||||||||||
| THR | C:40 | C:103 | 67.0 | 0.479 | -123.0 | 174.8 | NA | NA | NA | ||||||||||||||
| THR | D:40 | D:103 | 55.0 | 0.393 | -123.3 | 175.6 | NA | NA | NA | ||||||||||||||
| THR | E:40 | E:103 | 73.0 | 0.521 | -121.9 | 178.3 | NA | NA | NA | ||||||||||||||
| THR | F:40 | F:103 | 44.0 | 0.314 | -120.2 | 174.2 | NA | NA | NA | ||||||||||||||
| THR | G:40 | G:103 | 72.0 | 0.514 | -124.2 | 177.9 | NA | NA | NA | ||||||||||||||
| THR | H:40 | H:103 | 68.0 | 0.486 | -121.2 | 173.0 | NA | NA | NA | ||||||||||||||
| THR | I:40 | I:103 | 72.0 | 0.514 | -122.1 | 175.6 | NA | NA | NA | ||||||||||||||
| THR | J:40 | J:103 | 56.0 | 0.4 | -121.9 | 175.2 | NA | NA | NA | ||||||||||||||
| THR | K:40 | K:103 | 68.0 | 0.486 | -118.7 | 172.2 | NA | NA | NA | ||||||||||||||
| THR | L:40 | L:103 | 56.0 | 0.4 | -124.1 | 174.6 | NA | NA | NA | ||||||||||||||
| 6uxo | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 55.0 | 0.393 | -122.8 | 171.1 | 55.0 | 0.393 | 0.0 |
LMT HOH |
9.681 6.189 |
O O |
C2 O |
|||
| THR | B:40 | B:103 | 50.0 | 0.357 | -126.9 | 167.7 | 50.0 | 0.357 | 0.0 |
LMT HOH |
7.218 4.644 |
O O |
C3 O |
||||||||||
| THR | C:40 | C:103 | 54.0 | 0.386 | -118.3 | 172.4 | NA | NA | NA | ||||||||||||||
| THR | D:40 | D:103 | 32.0 | 0.229 | -131.0 | 173.5 | NA | NA | NA | ||||||||||||||
| THR | E:40 | E:103 | 66.0 | 0.471 | -121.4 | 171.5 | NA | NA | NA | ||||||||||||||
| THR | F:40 | F:103 | 38.0 | 0.271 | -134.6 | 171.5 | NA | NA | NA | ||||||||||||||
| THR | G:40 | G:103 | 65.0 | 0.464 | -123.4 | 177.2 | NA | NA | NA | ||||||||||||||
| THR | H:40 | H:103 | 36.0 | 0.257 | -118.2 | 172.7 | NA | NA | NA | ||||||||||||||
| THR | I:40 | I:103 | 56.0 | 0.4 | -119.3 | 176.0 | NA | NA | NA | ||||||||||||||
| THR | J:40 | J:103 | 54.0 | 0.386 | -129.4 | -179.9 | NA | NA | NA | ||||||||||||||
| THR | K:40 | K:103 | 46.0 | 0.329 | -125.3 | 171.3 | NA | NA | NA | ||||||||||||||
| THR | L:40 | L:103 | 41.0 | 0.293 | -131.7 | 176.6 | NA | NA | NA | ||||||||||||||
| 6uxp | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 47.0 | 0.336 | -128.8 | 174.7 | 47.0 | 0.336 | 0.0 |
HOH |
4.190 |
CG2 |
O |
|||
| THR | B:40 | B:103 | 52.0 | 0.371 | -131.8 | 166.8 | 52.0 | 0.371 | 0.0 |
HOH |
4.782 |
CG2 |
O |
||||||||||
| THR | C:40 | C:103 | 67.0 | 0.479 | -128.2 | 175.3 | NA | NA | NA | ||||||||||||||
| THR | D:40 | D:103 | 50.0 | 0.357 | -122.7 | 173.1 | NA | NA | NA | ||||||||||||||
| THR | E:40 | E:103 | 64.0 | 0.457 | -121.5 | 171.6 | NA | NA | NA | ||||||||||||||
| THR | F:40 | F:103 | 56.0 | 0.4 | -131.8 | 172.0 | NA | NA | NA | ||||||||||||||
| THR | G:40 | G:103 | 56.0 | 0.4 | -120.1 | 176.5 | NA | NA | NA | ||||||||||||||
| THR | H:40 | H:103 | 39.0 | 0.279 | -122.8 | 175.5 | NA | NA | NA | ||||||||||||||
| 6uxq | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 49.0 | 0.35 | -130.8 | 173.8 | 49.0 | 0.35 | 0.0 |
HOH |
3.518 |
CA |
O |
|||
| THR | B:40 | B:103 | 65.0 | 0.464 | -131.0 | 173.1 | 65.0 | 0.464 | 0.0 |
HOH |
2.679 |
OG1 |
O |
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| THR | C:40 | C:103 | 50.0 | 0.357 | -124.3 | 175.3 | NA | NA | NA | ||||||||||||||
| THR | D:40 | D:103 | 66.0 | 0.471 | -114.5 | 169.5 | NA | NA | NA | ||||||||||||||
| 6uxr | 1 | Q16611 | 100.0 | 3e-54 |
X-RAY |
2020-09-02 | THR | A:40 | A:103 | 63.0 | 0.45 | -126.6 | 166.0 | 63.0 | 0.45 | 0.0 |
HOH |
4.524 |
O |
O |
|||
| THR | B:40 | B:103 | 28.0 | 0.2 | -132.2 | 174.7 | 28.0 | 0.2 | 0.0 |
PGE HOH |
7.196 4.938 |
O O |
O2 O |
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| 4u2v | 1 | P42212,Q16611 | 100.0 | 7e-52 |
X-RAY |
2014-09-10 | THR | A:268 | B:1103 | 65.0 | 0.464 | -106.5 | 175.7 | 65.0 | 0.464 | 0.0 |
HOH |
9.263 |
CG2 |
O |
|||
| THR | B:268 | D:1103 | 63.0 | 0.45 | -105.8 | 176.3 | NA | NA | NA | ||||||||||||||
| THR | C:268 | C:1103 | 62.0 | 0.443 | -100.5 | 171.5 | 41.0 | 0.293 | 0.15 |
A:P42212+Q16611:0.15 |
HOH |
4.232 |
CG2 |
O |
|||||||||
| THR | D:268 | A:1103 | 65.0 | 0.464 | -102.4 | 171.5 | NA | NA | NA | ||||||||||||||
| 6odh | 1 | Q16611 | 100.0 | 1e-51 |
X-RAY |
2020-10-07 | THR | A:33 | A:103 | 75.0 | 0.536 | -119.9 | 173.1 | 75.0 | 0.536 | 0.0 |
SO4 |
7.120 |
OG1 |
O1 |
|||
| THR | B:33 | B:103 | 46.0 | 0.329 | -121.6 | 176.5 | 46.0 | 0.329 | 0.0 |
HOH |
6.611 |
O |
O |
||||||||||
| THR | C:33 | C:103 | 51.0 | 0.364 | -121.6 | 173.9 | NA | NA | NA | ||||||||||||||
| THR | D:33 | D:103 | 68.0 | 0.486 | -125.8 | 174.8 | NA | NA | NA | ||||||||||||||
| THR | E:33 | E:103 | 59.0 | 0.421 | -121.6 | 174.8 | NA | NA | NA | ||||||||||||||
| THR | F:33 | F:103 | 67.0 | 0.479 | -121.1 | 177.5 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q16611-f1 | 1 | Q16611 | 100.0 | 1e-157 | THR | A:103 | A:103 | 58.0 | 0.414 | -108.3 | 167.5 | ||