Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33543137 . C A CCDS4781.1:NM_001188.3:c.288atG>atT_NP_001179.1:p.96M>I Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 MSE A:81 A:96 83.0 0.449 H -81.1 -4.7 83.0 0.449 0.0 HOH
 2.773
 O
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 MET A:81 A:96 63.0 0.341 H -73.8 -21.5 63.0 0.341 0.0 HOH
 4.453
 CE
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 MET A:78 A:96 54.0 0.292 H -65.6 -35.7 54.0 0.292 0.0 HOH
 3.514
 CA
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 MET A:79 A:96 103.0 0.557 H -74.6 -37.2 14.0 0.076 0.481 B:None:0.481
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 MET A:76 A:96 110.0 0.595 H -64.2 -34.4 23.0 0.124 0.471 B:P55957:0.47
 HOH
 5.937
 N
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 MET A:79 A:96 39.0 0.211 H -61.5 -52.9 39.0 0.211 0.0 HOH
 7.501
 N
 O
MET B:79 B:96 111.0 0.6 H -65.3 -27.7 111.0 0.6 0.0 HOH
 6.295
 SD
 O
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 MSE A:74 A:96 58.0 0.314 H -56.8 -35.8 58.0 0.314 0.0 HOH
 8.220
 C
 O
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 90.0 0.486 H -65.9 -39.4 9.0 0.049 0.437 B:O43521:0.438
 TFA
EDO
CL
GOL
HOH
 7.802
3.502
3.760
6.354
4.753
 CE
SD
CG
C
SD
 F1
H22
CL
HO1
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 90.0 0.486 H -62.6 -32.4 14.0 0.076 0.41 C:O43521:0.411
 MPD
BR
 7.387
4.118
 CE
CG
 C5
BR
MET B:80 B:96 93.0 0.503 H -63.3 -32.3 14.0 0.076 0.427 D:O43521:0.427
 HOH
 8.486
 N
 O
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 93.0 0.503 H -65.7 -39.0 16.0 0.086 0.417 B:O43521:0.416
 HOH
 7.730
 O
 O
MET C:80 C:96 92.0 0.497 H -66.3 -38.9 16.0 0.086 0.411 D:O43521:0.411
 HOH
 7.088
 O
 O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 81.0 0.438 H -68.2 -43.5 12.0 0.065 0.373 B:O43521:0.373
 HOH
 3.876
 CG
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 78.0 0.422 H -66.5 -42.1 0.0 0.0 0.422 B:O43521:0.422
 1PG
HOH
 7.021
6.348
 SD
N
 C3
O
MET C:80 C:96 79.0 0.427 H -69.0 -40.1 1.0 0.005 0.422 D:O43521:0.422
 1PG
HOH
 7.004
5.787
 N
C
 O1
O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 MET A:80 A:96 87.0 0.47 H -69.2 -36.0 17.0 0.092 0.378 B:O43521:0.378
 HOH
 3.735
 CG
 O
MET C:80 C:96 97.0 0.524 H -62.5 -38.9 4.0 0.022 0.502 D:O43521:0.503
 HOH
 2.442
 SD
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 MET A:76 A:96 104.0 0.562 H -66.9 -40.1 22.0 0.119 0.443 B:P55957:0.443
 CU
HOH
 5.988
3.583
 CE
SD
 CU
O
MET C:76 C:96 93.0 0.503 H -68.5 -39.2 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 MET A:76 A:96 38.0 0.205 H -38.8 -50.7 5.0 0.027 0.178 B:Q16611:0.178
 CU
 8.353
 C
 CU
MET C:76 C:96 47.0 0.254 H -40.0 -48.9 NA NA NA
MET E:76 E:96 42.0 0.227 H -40.2 -48.8 NA NA NA
MET G:76 G:96 53.0 0.286 H -39.4 -49.1 NA NA NA
MET I:76 I:96 45.0 0.243 H -42.1 -44.8 NA NA NA
MET K:76 K:96 44.0 0.238 H -39.4 -48.4 NA NA NA
MET M:76 M:96 41.0 0.222 H -40.0 -49.7 NA NA NA
MET O:76 O:96 46.0 NA H -40.2 -48.6 NA NA NA
MET Q:76 Q:96 54.0 0.292 H -38.9 -50.3 NA NA NA
MET S:76 S:96 46.0 0.249 H -40.0 -49.2 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 MET A:80 A:96 51.0 0.276 H -59.6 -46.8 51.0 0.276 0.0 HOH
 3.665
 CB
 O
MET B:80 B:96 44.0 0.238 H -57.1 -54.1 44.0 0.238 0.0 HOH
 3.620
 CE
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 MET A:74 A:96 68.0 0.368 H -65.5 -46.3 68.0 0.368 0.0 ZN
HOH
 5.825
4.837
 O
N
 ZN
O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 MET A:32 A:96 96.0 0.519 H -67.2 -38.8 20.0 0.108 0.411 B:Q16611:0.411
MET B:32 B:96 75.0 0.405 H -68.0 -34.2 0.0 0.0 0.405 A:Q16611:0.405
MET C:32 C:96 84.0 0.454 H -67.7 -42.5 NA NA NA
MET D:32 D:96 84.0 0.454 H -64.4 -41.6 NA NA NA
MET E:32 E:96 85.0 0.459 H -64.0 -41.5 NA NA NA
MET F:32 F:96 129.0 0.697 H -71.1 -38.2 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 82.0 0.443 H -59.5 -42.4 2.0 0.011 0.432 B:Q16611:0.432
MET B:33 B:96 81.0 0.438 H -61.1 -38.3 3.0 0.016 0.422 A:Q16611:0.422
MET C:33 C:96 78.0 0.422 H -60.7 -43.9 NA NA NA
MET D:33 D:96 82.0 0.443 H -59.9 -37.9 NA NA NA
MET E:33 E:96 85.0 0.459 H -61.0 -40.8 NA NA NA
MET F:33 F:96 75.0 0.405 H -59.7 -38.9 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 81.0 0.438 H -66.0 -35.6 16.0 0.086 0.352 B:Q16611:0.351
 8SP
HOH
 6.789
8.417
 N
SD
 N
O
MET B:33 B:96 81.0 0.438 H -70.4 -38.5 15.0 0.081 0.357 A:Q16611:0.357
MET C:33 C:96 80.0 0.432 H -69.2 -33.5 NA NA NA
MET D:33 D:96 77.0 0.416 H -62.6 -39.3 NA NA NA
MET E:33 E:96 79.0 0.427 H -63.7 -38.0 NA NA NA
MET F:33 F:96 62.0 0.335 H -60.5 -37.2 NA NA NA
MET G:33 G:96 97.0 0.524 H -67.7 -39.1 NA NA NA
MET H:33 H:96 84.0 0.454 H -65.7 -36.5 NA NA NA
MET I:33 I:96 86.0 0.465 H -64.7 -36.4 NA NA NA
MET J:33 J:96 75.0 0.405 H -61.1 -43.4 NA NA NA
MET K:33 K:96 85.0 0.459 H -69.0 -37.4 NA NA NA
MET L:33 L:96 80.0 0.432 H -61.2 -41.8 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 76.0 0.411 H -59.2 -37.3 3.0 0.016 0.395 B:Q16611:0.395
 SO4
HOH
 8.038
4.764
 N
CG
 O1
O
MET B:33 B:96 80.0 0.432 H -57.6 -41.4 4.0 0.022 0.41 A:Q16611:0.411
 SO4
EDO
HOH
 9.576
7.078
4.048
 C
O
CG
 O3
O1
O
MET C:33 C:96 82.0 0.443 H -50.5 -46.5 NA NA NA
MET D:33 D:96 75.0 0.405 H -64.4 -44.3 NA NA NA
MET E:33 E:96 79.0 0.427 H -54.5 -51.4 NA NA NA
MET F:33 F:96 87.0 0.47 H -56.5 -44.0 NA NA NA
MET G:33 G:96 81.0 0.438 H -70.0 -27.3 NA NA NA
MET H:33 H:96 88.0 0.476 H -57.1 -43.8 NA NA NA
MET I:33 I:96 79.0 0.427 H -55.9 -40.6 NA NA NA
MET J:33 J:96 78.0 0.422 H -62.0 -40.2 NA NA NA
MET K:33 K:96 77.0 0.416 H -58.1 -41.2 NA NA NA
MET L:33 L:96 90.0 0.486 H -70.3 -31.0 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 74.0 0.4 H -68.3 -29.7 5.0 0.027 0.373 B:Q16611:0.373
 HOH
 7.850
 O
 O
MET B:33 B:96 72.0 0.389 H -65.1 -39.2 9.0 0.049 0.34 A:Q16611:0.341
 HOH
 7.532
 CE
 O
MET C:33 C:96 82.0 0.443 H -61.1 -37.8 NA NA NA
MET D:33 D:96 80.0 0.432 H -66.6 -38.9 NA NA NA
MET E:33 E:96 90.0 0.486 H -58.4 -39.7 NA NA NA
MET F:33 F:96 94.0 0.508 H -57.5 -43.2 NA NA NA
MET G:33 G:96 79.0 0.427 H -63.5 -38.5 NA NA NA
MET H:33 H:96 75.0 0.405 H -65.2 -41.7 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 87.0 0.47 H -58.3 -41.8 24.0 0.13 0.34 B:Q16611:0.341
 SO4
HOH
 7.825
2.813
 N
O
 O1
O
MET B:33 B:96 83.0 0.449 H -57.6 -44.1 2.0 0.011 0.438 A:Q16611:0.438
 HOH
 5.731
 N
 O
MET C:33 C:96 78.0 0.422 H -58.3 -42.6 NA NA NA
MET D:33 D:96 70.0 0.378 H -67.5 -38.8 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 MET A:33 A:96 82.0 0.443 H -62.7 -42.0 18.0 0.097 0.346 B:Q16611:0.346
 HOH
 2.602
 O
 O
MET B:33 B:96 95.0 0.514 H -57.1 -38.5 13.0 0.07 0.444 A:Q16611:0.443
 HOH
 2.986
 O
 O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 MET A:261 B:1096 87.0 0.47 H -57.0 -48.8 4.0 0.022 0.448 C:P42212+Q16611:0.449
 HOH
 2.685
 O
 O
MET B:261 D:1096 78.0 0.422 H -57.9 -49.0 NA NA NA
MET C:261 C:1096 80.0 0.432 H -61.4 -49.3 14.0 0.076 0.356 A:P42212+Q16611:0.357
 HOH
 6.342
 N
 O
MET D:261 A:1096 91.0 0.492 H -61.6 -48.8 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 MET A:26 A:96 97.0 0.524 H -63.5 -31.3 5.0 0.027 0.497 B:Q16611:0.497
MET B:26 B:96 88.0 0.476 H -66.0 -33.1 9.0 0.049 0.427 A:Q16611:0.427
MET C:26 C:96 77.0 0.416 H -63.4 -31.0 NA NA NA
MET D:26 D:96 81.0 0.438 H -67.5 -31.9 NA NA NA
MET E:26 E:96 73.0 0.395 H -65.4 -32.6 NA NA NA
MET F:26 F:96 62.0 0.335 H -66.7 -28.4 NA NA NA
3qbr 2 Q16611 100.0 3e-17 X-RAY
 2011-04-13 MET B:34 NA:NA DO NA DO DO DO NA NA NA
MET D:34 NA:NA DO NA DO DO DO NA NA NA
5fmk 2 Q16611 100.0 3e-17 X-RAY
 2016-06-01 MET B:34 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 MET A:96 A:96 11.0 0.059 H -61.1 -50.4