Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 33543199 . G A CCDS4781.1:NM_001188.3:c.226Cgg>Tgg_NP_001179.1:p.76R>W Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ims 1 Q16611 100.0 2e-126 X-RAY
 2006-12-26 ARG A:61 A:76 114.0 0.507 H -58.1 -48.8 114.0 0.507 0.0 HOH
 2.707
 NE
 O
2imt 1 Q16611 100.0 2e-126 X-RAY
 2007-01-23 ARG A:61 A:76 118.0 0.524 H -68.7 -45.5 118.0 0.524 0.0 HOH
 2.815
 NE
 O
2jcn 1 Q16611 100.0 5e-126 X-RAY
 2007-01-04 ARG A:58 A:76 108.0 0.48 H -64.9 -41.2 108.0 0.48 0.0 HOH
 3.594
 NE
 O
2m5b 1 Q16611 100.0 8e-125 NMR
 2013-04-17 ARG A:59 A:76 138.0 0.613 H -54.6 -56.4 138.0 0.613 0.0
7m5a 1 Q16611 99.4 2e-121 X-RAY
 2022-01-12 ARG A:56 A:76 88.0 0.391 H -61.2 -47.3 88.0 0.391 0.0 HOH
 3.064
 O
 O
4u2u 1 Q16611 98.21 1e-120 X-RAY
 2014-09-10 ARG A:59 A:76 89.0 0.396 H -63.0 -49.4 89.0 0.396 0.0 HOH
 3.560
 NH2
 O
ARG B:59 B:76 114.0 0.507 H -67.5 -41.9 114.0 0.507 0.0 HOH
 3.394
 NH2
 O
2yv6 1 Q16611 100.0 2e-120 X-RAY
 2008-04-15 ARG A:54 A:76 99.0 0.44 H -62.3 -51.0 99.0 0.44 0.0
5vwv 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 125.0 0.556 H -60.7 -44.4 125.0 0.556 0.0 EDO
EDO
HOH
 2.644
6.135
2.914
 NH1
NH2
NE
 H11
H21
O
5vww 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 56.0 0.249 H -66.0 -44.0 56.0 0.249 0.0
ARG B:60 B:76 69.0 0.307 H -65.3 -42.8 68.0 0.302 0.005 A:Q16611:0.004
5vwx 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 64.0 0.284 H -76.5 -41.4 64.0 0.284 0.0 HOH
 3.651
 NH2
 O
ARG C:60 C:76 71.0 0.316 H -76.6 -41.5 71.0 0.316 0.0 HOH
 7.511
 O
 O
5vwy 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 101.0 0.449 H -58.6 -48.6 101.0 0.449 0.0 HOH
 3.286
 CD
 O
5vwz 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 118.0 0.524 H -66.3 -47.4 118.0 0.524 0.0 HOH
 2.870
 NE
 O
ARG C:60 C:76 113.0 0.502 H -59.1 -49.6 113.0 0.502 0.0 HOH
 2.390
 NH1
 O
5vx0 1 Q16611 98.21 2e-120 X-RAY
 2017-11-15 ARG A:60 A:76 62.0 0.276 H -63.3 -46.4 62.0 0.276 0.0 MG
HOH
 3.220
2.915
 NE
NH2
 MG
O
ARG C:60 C:76 80.0 0.356 H -63.3 -47.1 80.0 0.356 0.0 HOH
 2.070
 NH2
 O
7m5b 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ARG A:56 A:76 123.0 0.547 H -67.7 -43.4 123.0 0.547 0.0 HOH
 3.843
 NH1
 O
ARG C:56 C:76 121.0 0.538 H -64.0 -45.2 NA NA NA
7m5c 1 Q16611 98.8 4e-120 X-RAY
 2022-01-12 ARG A:56 A:76 76.0 0.338 H -65.8 -44.7 76.0 0.338 0.0
ARG C:56 C:76 77.0 0.342 H -61.7 -51.4 NA NA NA
ARG E:56 E:76 115.0 0.511 H -64.4 -46.7 NA NA NA
ARG G:56 G:76 89.0 0.396 H -69.4 -45.3 NA NA NA
ARG I:56 I:76 108.0 0.48 H -64.6 -44.0 NA NA NA
ARG K:56 K:76 100.0 0.444 H -64.6 -46.8 NA NA NA
ARG M:56 M:76 102.0 0.453 H -64.2 -46.0 NA NA NA
ARG O:56 O:76 108.0 0.48 H -67.7 -46.2 NA NA NA
ARG Q:56 Q:76 117.0 0.52 H -65.7 -45.2 NA NA NA
ARG S:56 S:76 118.0 0.524 H -63.1 -47.5 NA NA NA
5vx1 1 Q16611 97.62 9e-120 X-RAY
 2017-11-15 ARG A:60 A:76 71.0 0.316 H -60.1 -49.1 61.0 0.271 0.045 B:Q16611:0.044
 HOH
 2.320
 NH1
 O
ARG B:60 B:76 117.0 0.52 H -61.5 -47.8 98.0 0.436 0.084 A:Q16611:0.084
 HOH
 2.919
 NH2
 O
5fmi 1 Q16611 98.77 3e-117 X-RAY
 2016-06-01 ARG A:54 A:76 115.0 0.511 H -63.3 -47.8 115.0 0.511 0.0 HOH
 2.737
 NE
 O
7k02 1 Q16611 99.17 2e-85 X-RAY
 2021-03-31 ARG A:12 A:76 145.0 0.644 H -75.5 -35.4 145.0 0.644 0.0
ARG B:12 B:76 176.0 0.782 H -72.8 -33.6 176.0 0.782 0.0
ARG C:12 C:76 180.0 0.8 H -78.0 -30.3 NA NA NA
ARG D:12 D:76 179.0 0.796 H -70.5 -36.9 NA NA NA
ARG E:12 E:76 161.0 0.716 H -52.1 -47.4 NA NA NA
ARG F:12 F:76 177.0 0.787 H -73.1 -38.6 NA NA NA
6uxm 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 145.0 0.644 H -72.7 -32.7 145.0 0.644 0.0
ARG B:13 B:76 154.0 0.684 H -71.8 -34.2 154.0 0.684 0.0
ARG C:13 C:76 144.0 0.64 H -72.6 -31.6 NA NA NA
ARG D:13 D:76 150.0 0.667 H -73.1 -31.6 NA NA NA
ARG E:13 E:76 162.0 0.72 H -75.3 -33.0 NA NA NA
ARG F:13 F:76 157.0 0.698 H -73.7 -31.2 NA NA NA
6uxn 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 130.0 0.578 H -70.4 -27.9 108.0 0.48 0.098 B:Q16611:0.098
 SO4
HOH
 3.288
3.945
 NE
CG
 O4
O
ARG B:13 B:76 156.0 0.693 H -71.6 -28.9 135.0 0.6 0.093 A:Q16611:0.093
 SO4
HOH
 2.579
8.685
 NH1
O
 O2
O
ARG C:13 C:76 131.0 0.582 H -73.0 -33.6 NA NA NA
ARG D:13 D:76 160.0 0.711 H -70.4 -28.3 NA NA NA
ARG E:13 E:76 157.0 0.698 H -67.5 -30.6 NA NA NA
ARG F:13 F:76 160.0 0.711 H -68.2 -30.4 NA NA NA
ARG G:13 G:76 128.0 0.569 H -73.6 -30.0 NA NA NA
ARG H:13 H:76 164.0 0.729 H -69.7 -31.1 NA NA NA
ARG I:13 I:76 129.0 0.573 H -67.1 -31.7 NA NA NA
ARG J:13 J:76 126.0 0.56 H -65.1 -33.7 NA NA NA
ARG K:13 K:76 121.0 0.538 H -70.7 -31.7 NA NA NA
ARG L:13 L:76 158.0 0.702 H -69.0 -34.8 NA NA NA
6uxo 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 143.0 0.636 H -66.7 -34.2 120.0 0.533 0.103 B:Q16611:0.102
 SO4
SO4
ACT
HOH
 2.443
2.957
5.981
3.163
 NH2
NH1
O
NH2
 O4
O3
O
O
ARG B:13 B:76 149.0 0.662 H -67.5 -35.3 125.0 0.556 0.106 A:Q16611:0.107
 SO4
HOH
 2.875
3.277
 NH2
CG
 O2
O
ARG C:13 C:76 126.0 0.56 H -69.3 -35.7 NA NA NA
ARG D:13 D:76 146.0 0.649 H -70.2 -34.5 NA NA NA
ARG E:13 E:76 153.0 0.68 H -70.3 -32.3 NA NA NA
ARG F:13 F:76 161.0 0.716 H -69.7 -36.0 NA NA NA
ARG G:13 G:76 126.0 0.56 H -69.2 -32.9 NA NA NA
ARG H:13 H:76 154.0 0.684 H -71.4 -34.3 NA NA NA
ARG I:13 I:76 126.0 0.56 H -63.4 -32.6 NA NA NA
ARG J:13 J:76 148.0 0.658 H -70.4 -34.6 NA NA NA
ARG K:13 K:76 149.0 0.662 H -71.6 -30.6 NA NA NA
ARG L:13 L:76 129.0 0.573 H -69.6 -33.4 NA NA NA
6uxp 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 161.0 0.716 H -74.1 -30.1 143.0 0.636 0.08 B:Q16611:0.08
 HOH
 8.159
 O
 O
ARG B:13 B:76 151.0 0.671 H -76.6 -33.5 143.0 0.636 0.035 A:Q16611:0.036
 HOH
 7.642
 NH1
 O
ARG C:13 C:76 151.0 0.671 H -77.6 -30.5 NA NA NA
ARG D:13 D:76 158.0 0.702 H -68.9 -38.7 NA NA NA
ARG E:13 E:76 156.0 0.693 H -69.7 -40.6 NA NA NA
ARG F:13 F:76 153.0 0.68 H -67.6 -42.6 NA NA NA
ARG G:13 G:76 101.0 0.449 H -77.5 -29.3 NA NA NA
ARG H:13 H:76 158.0 0.702 H -75.0 -28.0 NA NA NA
6uxq 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 133.0 0.591 H -72.7 -34.5 114.0 0.507 0.084 B:Q16611:0.084
 HOH
 2.491
 NH2
 O
ARG B:13 B:76 141.0 0.627 H -72.5 -35.7 124.0 0.551 0.076 A:Q16611:0.076
 C8E
EDO
EDO
HOH
 7.732
9.232
3.067
2.848
 CD
NH1
NH2
NH1
 C16
O2
O1
O
ARG C:13 C:76 151.0 0.671 H -71.1 -31.5 NA NA NA
ARG D:13 D:76 154.0 0.684 H -71.6 -33.1 NA NA NA
6uxr 1 Q16611 100.0 3e-54 X-RAY
 2020-09-02 ARG A:13 A:76 160.0 0.711 H -63.9 -40.4 144.0 0.64 0.071 B:Q16611:0.071
 HOH
 3.349
 NH2
 O
ARG B:13 B:76 163.0 0.724 H -65.5 -37.9 149.0 0.662 0.062 A:Q16611:0.062
 HOH
 2.668
 NH1
 O
4u2v 1 P42212,Q16611 100.0 7e-52 X-RAY
 2014-09-10 ARG A:241 B:1076 136.0 0.604 H -67.6 -34.3 110.0 0.489 0.115 C:P42212+Q16611:0.116
 HOH
 3.453
 NH2
 O
ARG B:241 D:1076 139.0 0.618 H -67.1 -37.6 NA NA NA
ARG C:241 C:1076 113.0 0.502 H -68.9 -38.8 113.0 0.502 0.0 HOH
 3.617
 NH1
 O
ARG D:241 A:1076 120.0 0.533 H -68.6 -40.0 NA NA NA
6odh 1 Q16611 100.0 1e-51 X-RAY
 2020-10-07 ARG A:6 A:76 174.0 0.773 H -70.8 -38.3 174.0 0.773 0.0
ARG B:6 B:76 161.0 0.716 H -69.4 -38.7 156.0 0.693 0.023 A:Q16611:0.022
ARG C:6 C:76 165.0 0.733 H -77.9 -15.9 NA NA NA
ARG D:6 D:76 166.0 0.738 H -73.2 -32.3 NA NA NA
ARG E:6 E:76 159.0 0.707 H -80.6 -25.2 NA NA NA
ARG F:6 F:76 164.0 0.729 H -63.8 -30.1 NA NA NA
3qbr 2 Q16611 100.0 3e-17 X-RAY
 2011-04-13 ARG B:14 B:10 162.0 0.72 H -86.2 -29.1 116.0 0.516 0.204 A:Q5BWX6:0.204
 HOH
 4.047
 CA
 O
ARG D:14 Y:10 145.0 0.644 H -73.0 -43.9 NA NA NA
5fmk 2 Q16611 100.0 3e-17 X-RAY
 2016-06-01 ARG B:14 B:76 134.0 0.596 H -62.8 -42.1 67.0 0.298 0.298 A:Q07817:0.298
 GOL
HOH
 8.077
2.461
 NH2
NH2
 C1
O
2jby 2 Q13014 100.0 1e-11 X-RAY
 2007-03-27 ARG B:10 B:76 150.0 0.667 H -48.3 -58.9 150.0 0.667 0.0 HOH
 2.575
 NE
 O
2xpx 2 Q16611 100.0 1e-11 X-RAY
 2011-01-26 ARG B:10 B:76 129.0 0.573 H -76.3 -39.1 121.0 0.538 0.035 A:P03182:0.036
 HOH
 5.320
 O
 O
4uf1 2 Q16611 100.0 1e-11 X-RAY
 2015-08-05 ARG B:10 B:76 105.0 0.467 H -57.7 -43.7 105.0 0.467 0.0 HOH
 2.206
 HH22
 O
5ajk 2 Q16611 100.0 1e-11 X-RAY
 2015-03-25 ARG B:10 B:76 156.0 0.693 H -62.4 -34.3 156.0 0.693 0.0 HOH
 6.940
 O
 O
ARG D:10 D:76 146.0 0.649 H -60.5 -37.8 142.0 0.631 0.018 C:Q85365:0.018
 HOH
 5.189
 O
 O
ARG F:10 F:76 133.0 0.591 H -64.2 -35.6 NA NA NA
ARG H:10 H:76 147.0 0.653 H -63.9 -35.1 NA NA NA
ARG J:10 J:76 152.0 0.676 H -68.4 -46.9 NA NA NA
ARG L:10 L:76 135.0 0.6 H -63.6 -38.5 NA NA NA
4d2l 2 Q16611 92.31 2e-10 X-RAY
 2014-06-04 ARG B:10 B:60 156.0 0.693 H -52.3 -45.6 155.0 0.689 0.004 A:O57173:0.004
2voh 2 O08734 80.77 4e-09 X-RAY
 2008-03-04 ARG B:10 B:73 139.0 0.618 H -66.0 -31.9 97.0 0.431 0.187 A:Q07440:0.187
 SO4
HOH
 2.989
2.496
 NH2
O
 O1
O
7m5c 2 Q16611 100.0 3e-08 X-RAY
 2022-01-12 ARG B:9 B:76 162.0 0.72 H -69.2 -34.9 134.0 0.596 0.124 A:Q16611:0.124
ARG D:9 D:76 125.0 NA H -64.3 -41.4 NA NA NA
ARG F:9 F:76 198.0 0.88 H -64.0 -40.4 NA NA NA
ARG H:9 H:76 161.0 0.716 H -66.6 -36.7 NA NA NA
ARG J:9 J:76 140.0 0.622 H -66.0 -39.1 NA NA NA
ARG L:9 L:76 168.0 0.747 H -66.3 -34.2 NA NA NA
ARG N:9 N:76 164.0 0.729 H -65.9 -36.4 NA NA NA
ARG P:9 P:76 158.0 0.702 H -65.9 -36.0 NA NA NA
ARG R:9 R:76 172.0 0.764 H -70.7 -35.7 NA NA NA
ARG T:9 T:76 147.0 0.653 H -66.2 -39.7 NA NA NA
3i1h 2 Q16611 100.0 1.0 X-RAY
 2009-07-14 ARG B:5 B:76 155.0 0.689 H -62.5 -35.7 62.0 0.276 0.413 A:Q16548:0.413
 HOH
 5.181
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16611-f1 1 Q16611 100.0 1e-157 ARG A:76 A:76 131.0 0.582 H -57.9 -49.1