Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 18134076 . T A CCDS4543.1:NM_000367.2:c.539tAt>tTt_NP_000358.1:p.180Y>F Homo sapiens thiopurine S-methyltransferase (TPMT), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2bzg 1 P51580 100.0 1e-174 X-RAY
 2005-08-25 TYR A:167 A:180 0.0 0.0 E -104.1 111.2 0.0 0.0 0.0 HOH
 6.775
 N
 O
2h11 1 O43213 100.0 1e-174 X-RAY
 2006-11-21 TYR A:167 A:180 0.0 0.0 E -105.6 108.0 0.0 0.0 0.0 HOH
 6.656
 O
 O
TYR B:167 B:180 0.0 0.0 E -108.9 109.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p51580-f1 1 P51580 100.0 0.0 TYR A:180 A:180 0.0 0.0 E -101.1 111.8